480results about How to "Quick seal" patented technology

A bipolar electrosurgical instrument has opposable seal surfaces on its jaws for grasping and sealing vessels and vascular tissue. Inner and outer instrument members allow arcuate motion of the seal surfaces. An open lockbox provides a pivot with lateral support to maintain alignment of the lateral surfaces. Ratchets on the instrument members hold a constant closure force on the tissue during the seal process. A shank portion on each member is tuned to provide an appropriate spring force to hold the seal surfaces together. During surgery, the instrument can be used to grasp and clamp vascular tissue and apply bipolar electrosurgical current through the clamped tissue. In one embodiment, the seal surfaces are partially insulated to prevent a short circuit when the instrument jaws are closed together. In another embodiment, the seal surfaces are removably mounted on the jaws.

A suction cannula, dilator, stapler and staple are provided herein. The suction cannula is concentrically aligned with a puncture site (e.g., puncture in an artery or vein) and provides vacuum about the periphery of the puncture site so that the puncture hole is always located during a medical procedure, and to thereby permit a surgeon to quickly and efficiently close the puncture using, for example, a stapling device. In the preferred embodiment the suction cannula has a tube-in-tube construction having an inner tube and an outer tube where a vacuum can be applied between the tubes. The dilator (and suction cannula) centers around a guide wire (that is already in place within the venous structure) and follows the path of the guide wire to the puncture site. Preferably, the dilator has a tapered tip on the distal end that enters a hole made in the vein or artery. A blood indicator is provided on the proximal end to provide visual feedback when the surgeon is in the artery (i.e., pulsating blood indicates that the tip of the dilator is in the artery). Also preferably, the dilator includes a tapered tip on the distal end that is radially collapsible so that the dilator can be withdrawn from the artery and the suction cannula is thereby permitted to advance over the dilator to the artery wall. The stapler is provided which holds a multi-pronged staple on a shaft at the distal end. The stapler is constructed to slide into the suction cannula (i.e., the inner tube of the cannula) to approach the puncture in the artery, to permit the stapling of the artery. Preferably, the distal end of the stapler includes a T-flange that holds a staple and a crimping mechanism that crimps the staple into the artery, thereby sealing the puncture. The T-flange permits the staple to be held and inserted into the artery wall. An oval hub on the T-flange is provided that mates with an oval hole in the center of the staple. To hold a staple, a staple is placed on the hub and rotated 90 degrees, thereby affixing the staple to the stapler. Once the staple is crimped onto the artery wall, the shaft can be rotated 90 degrees, thereby aligning the oval hub and the oval hole, so that the stapler can be removed. Preferably, the staple includes a plurality of prongs that are inserted into the vascular wall.

A modification to allow delivery of a two port medical flow restrictor over a guidewire, and a means to mechanically collapse the new device. A thin walled, foil-like shell, is compacted for delivery. The invention includes the device, delivery assemblies, and methods of placing, and using, the device. A device with an aneurysm lobe and an artery lobe self-aligns its waist at the neck of an aneurysm as the device shell is pressure expanded. Mechanical force collapses both the aneurysm lobe and the artery lobe, captivating the neck of the aneurysm and securing the device. The device works for aneurysms at bifurcations and aneurysms near side-branch arteries. The device, unlike endovascular coiling, excludes the weak neck of the aneurysm from circulation, while leaving the aneurysm relatively empty. Unlike stent-based exclusion, the device does not block perforator arteries. This exclusion device can also limit flow through body lumens or orifices.

In a microfluidic system, a magnetic clamp for sealing a flexible microchannel chip includes a base formed from a magnetically-attractable material. The base supports a window for viewing the face of the microfluidic chip. A ring with magnets uniformly distributed around it is disposed over the base. A transparent disk attached to the top of the ring has an inlet and an outlet for introducing and removing a fluid medium into a cavity defined the disk, the window, the center opening of the ring and the base. An elastomer cushion is attached to the inner surface of the disk. The magnetic force between the base and the magnets on the ring compresses the cushion against the microfluidic chip so that the microchannels are sealed against the window with a uniform and reproducible pressure.

A dispensing valve is provided for dispensing fluid products. The valve includes a marginal portion, a flexible valve head with a discharge orifice therein, and a flexible connector sleeve having one end connected with the marginal portion and the opposite end connected with the valve head adjacent a marginal edge thereof.

Biodegradable resorbable drug delivery systems characterized by an electrospun biodegradable resorbable polymeric fiber matrix with at least one therapeutic agent incorporated into the fibers of the matrix, wherein the fiber matrix has an interfibrillar space of at least 65% by volume. Therapeutic methods for delivering a chemotherapeutic agent to body cavities from which a tumor has been excised and for strengthening weakened blood vessel walls are also disclosed.

An extrusion system utilizes single or tandem extruders and a mixer-cooler to extrude a foamable extrudate through a die in a sealable chamber. The foamable extrudate is shaped and calibrated within the chamber. The die is mounted on the end of a gel tube projecting through a gland seal in a fixed bulkhead forming the upstream end of the chamber. The gel tube and mixer-cooler are mounted on a movable carriage, movement of which may be used to adjust the die with respect to shaping and calibrating equipment inside the chamber. The mixer-cooler achieves a selected narrow range of uniform viscosity of the melt at the die depending on the size of the product and density. The chamber is preferably a vacuum chamber producing low density foams. The product exits the chamber to atmosphere on a continuous basis through a submerged orifice in a water baffle immersion seal. The mixer-cooler enables a large size low density product to be produced with uniform cellular structure without cell collapse or density gradients, as the product is subjected to the pressure and temperature transformations passing from the chamber to atmosphere through the water. The seal includes the submerged orifice with a free wheeling guiding system upstream of the orifice. Immediately ahead of the guiding system, the parameters of the foam extrudate are sensed to control the configuration of the orifice on a continuous basis. Before the extrudate passes into the water baffle seal it moves over a floating dancer roll, the position of which controls a haul-off such as a vacuum belt at the tail end of the system. This avoids pushing on the extrudate.

The invention relates to a polydimethylsiloxane micro-fluidic chip and a preparation method thereof. The polydimethylsiloxane micro-fluidic chip is characterized in that the polydimethylsiloxane micro-fluidic chip consists of three layers of base materials, wherein the upper layer is a polydimethylsiloxane cover layer, the middle layer is a double-sided rubber layer, and the lower layer is a polydimethylsiloxane basal layer; and the micro-fluidic chip is prepared by adhering the upper and lower layers of base materials and the middle layer. The preparation method is characterized by comprising the following steps in sequence: (1) designing and drawing micro-channels of the micro-fluidic chip by using computer-aided design software; (2) processing the micro-channels as well as sample inlets on the base materials of the chip through a micro-processing technology; and (3) aligning, pressing and sealing the three layers of base materials to prepare the micro-fluidic chip. The polydimethylsiloxane micro-fluidic chip and the preparation method thereof have the advantages that no generator or ultraviolet irradiation equipment needs to be used in the preparation of the polydimethylsiloxane micro-fluidic chip provided by the invention, and rapid sealing of the polydimethylsiloxane can be realized.

A multi-layer film for vertical form, film and seal systems for liquid, powder, granules and/or other flowables packaging, said multi-layer comprising: an inner layer made of polyethylene, a blend of polyethylenes or ethylene copolymers; a core, comprising one or more than one layer, made from a blend of polypropylene, linear low density polyethylene, a polymer compatibilizer or tie-layer resin, and/or low density polyethylene, said core being applied against the inner layer; and an outer layer (same or different from the inner layer or the core layer) is made of a polyethylene or a blend of polyethylenes with or without ethylene copolymers, said outer layer being applied against the core and opposite the inner layer; said multi-layer film having an overall thickness of lower or equal to 2.5 mil and at least one of the properties listed hereinafter: a stiffness (as measured by 1% secant modulus in the film direction) varying from 79000 psi to 140000 psi; a tensile strength at yield of from 2100 psi to 3300 psi; (measured in film machine direction) and a tensile strength at break of from 4700 to 6700 psi (measured in film machine direction). A method of forming, sealing and filling a pouch with said film, a pouch formed with said film and use of said film to form a pouch.

The present invention provides a water balloon with a quick, easy, and low-cost means for sealing the balloon orifice. For example, the water balloon may comprise a liquid-activated closure mechanism along the inside of the balloon neck. A user then activates the closure mechanism while filling the balloon with water and may then seal the balloon orifice by pinching the balloon neck.

The invention discloses a low-pressure pilot operated safety valve. The valve comprises an execution mechanism, a transmission mechanism and a conversion mechanism, wherein the execution mechanism consists of a main valve body, a valve rod and a valve core; the transmission mechanism of a balance air chamber consists of a partition board, a cylinder, a piston and a diaphragm assembly; the conversion mechanism of a control air chamber consists of a pilot valve seat, a valve core cover, a diaphragm assembly and a pilot valve core; the pilot valve core can quickly perform air chamber sealing conversion between the pilot valve seat and the valve core cover when sensing the pressure change and moving up and down, and pressure in the control air chamber and the balance air chamber is quickly converted by switching an external drain hole; and by increasing and reducing the area of the air chambers, the main valve can be quickly opened to exhaust air and relieve pressure so as to ensure the safety, and the main valve can be accurately and stably seated and tightly closed. The valve has novel design and simple structure, the excessive pressure is only 1 to 3 percent, the opening precision is very high, the response speed is very high, the seating pressure range is a fixed value, the seating reset is accurate and reliable, and the valve has very good market prospect.

The invention relates to a Niuhuangshangqing soft capsule and a preparation method thereof, as well as a quality control method of capsule contents. The Niuhuangshangqing soft capsule comprises contents and capsule shell. The contents include an extent of Chinese medicinal materials in Niuhuangshangqing prescription and a dispersion medium with a weight ratio of 1:(1-2), wherein, the dispersion medium is vegetable oil. The soft capsule is prepared by extracting effective components from Chinese medicinal materials in Niuhuangshangqing prescription in accordance with the properties of the effective components by using different modern extraction techniques and making into soft capsule. The soft capsule has embedding and masking effects, and can prevent volatilization loss of oil components and oxygenation or photodecomposition of effective components. The soft capsule also has the advantages of rapid disintegration, uniform dispersion, high bioavailability, good stability of effective components, low liability of moisture absorption, good air tightness, direct intestinal absorption after disintegration, masking of unpleasant odors of effective components, convenience for administration and carrying, and so on.

An extrusion system utilizes single or tandem extruders and a mixer-cooler to extrude a foamable extrudate through a die in a sealable chamber. The foamable extrudate is shaped and calibrated within the chamber. The die is mounted on the end of a gel tube projecting through a gland seal in a fixed bulkhead forming the upstream end of the chamber. The gel tube and mixer-cooler are mounted on a movable carriage, movement of which may be used to adjust the die with respect to shaping and calibrating equipment inside the chamber. The mixer-cooler achieves a selected narrow range of uniform viscosity of the melt at the die depending on the size of the product and density. The chamber is preferably a vacuum chamber producing low density foams. The product exits the chamber to atmosphere on a continuous basis through a submerged orifice in a water baffle immersion seal. The mixer-cooler enables a large size low density product to be produced with uniform cellular structure without cell collapse or density gradients, as the product is subjected to the pressure and temperature transformations passing from the chamber to atmosphere through the water. The seal includes the submerged orifice with a free wheeling guiding system upstream of the orifice. Immediately ahead of the guiding system, the parameters of the foam extrudate are sensed to control the configuration of the orifice on a continuous basis. Before the extrudate passes into the water baffle seal it moves over a floating dancer roll, the position of which controls a haul-off such as a vacuum belt at the tail end of the system. This avoids pushing on the extrudate.

The invention discloses a rectangular vacuum insulation structural board and a heat preservation box assembled by the rectangular vacuum insulation structural board. According to the structural board, a vacuum insulation board is arranged between a rigid inner side face board and a rigid outer side face board which are identical in size through polyurethane (PU) expanded plastics or other insulated adhesives in a clamping mode, side edge strips are not arranged on the periphery between the inner side face board and the outer side face board. According to the heat preservation box, a rectangular box frame is formed by four rectangular angle connecting blocks, eight seamed edge section bars and four box opening section bars. The bottom of the box frame and four side faces of the box frame are respectively provided with rectangular vacuum insulation structural boards, and a box body with an opening at the upper end is formed. A rectangular ring-shaped door sealing strip is arranged on the periphery of the opening of the box body in a sleeved mode, and four sides of the rectangular ring-shaped door sealing strip are provided with magnet strips. A rectangular vacuum insulation structural board forms a door board which is buckled on the opening of the box body and seals the opening of the box body, wherein four sides of the rectangular vacuum insulation structural board are provided with edge sealing section bars, a steel board strip is arranged on the surface, facing the box body, of each edge sealing section bar of the door board, and each steel board strip is absorbed with each magnet strip corresponding to the door sealing strip. The rectangular vacuum insulation structural board is good in rigidity, high in appearance size precision, good in decorative performance and convenient to assemble and install.

The invention relates to an SMS composite packaging material with multi-components and a production method thereof. The material includes two layers of spun-bonded fiber MINERVA and an interlayer which is a layer of melt-blown fiber. The MINERVA layers are bonded with a melt-blown layer through heat boning, acupuncture, spun-lace or ultrasonic; the MINERVA layers comprise two-component fiber and the melt-blown layer comprises one-component fiber. The production method includes the following processes: the fiber ejected by a spun-bonded machinery forms a web; when a web curtain moves to a melt-blown machinery, the melt-blown machinery ejects filaments to the moved web curtain; the web curtain continues to move to the spun-bonded machinery and the filaments are spread on the web curtain by the spun-bonded machinery ejects; at last, the process of strengthening the fiber and the web is carried out to obtain the martial in the invention. The invention not only can be widely used in the packaging material, but also can be used in the aspects of composition, surface-covering, a series of medical composite cloth and electrical wipes. Besides, the invention has the advantages of low melting point, fast sealing, high intensity and uneasy material spilling as well as favorable permeability and low cost.

Between an optical fiber (LF11, LFB12, LFB13) and a surrounding core covering (AH11, AH12, SB13) of an optical transmission element (OE11 to OE13) there is at least one dry and compressible fixating element (FE11 to FE13), which surrounds the optical fiber totally or partially, and which exerts a defined contact pressure against the core covering and against the optical fiber for fixating the optical fiber in the longitudinal direction of the transmission element. The fixating element is further formed and positioned in such a way, that position changes of the optical fiber due to bending or elongation are possible. In this way, unallowable attenuation increases in the optical fiber due to bending or position changes can be avoided.

The invention provides a measuring device for a concrete permeation coefficient. The device comprises a water injecting chamber, a water inlet pipe, an overflow pipe, a water storage container, an upper annular tray, a lower annular tray, a support frame, a lifting mechanism, a permeating water collecting funnel, a permeating water guiding pipe, a weighting container and an intelligent measuring system, wherein the water injecting chamber is communicated with the water storage container through the water inlet pipe and the overflow pipe; the support frame is respectively fixedly connected with the lower annular tray on the upper side and the lifting mechanism on the lower side; the upper annular tray is fixedly connected with the lower edge of the water injecting chamber; a sealing cushion is arranged on the lower surface of the upper annular tray; the lower annular tray is fixedly connected with the upper end of the support frame; a sealing gasket is arranged on the upper surface of the lower annular tray; the permeating water collecting funnel is arranged in the support frame; the bottom of the permeating water collecting funnel is connected with the weighting container through the permeating water guiding pipe; the intelligent measuring system is used for calculating the permeation coefficient of a test piece according to a fixed formula based on the measured time, and corresponding permeating water quality. The measuring device provided by the invention has a simple structure, high measurement precision and high measurement repeatability; the measuring method is quick and convenient and is suitable for the measurement for the concrete permeation coefficient in any places; and the invention also provides a method for measuring the concrete permeation coefficient by adopting the measuring device.