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Compound trauma cream and preparation method thereof

Funing Ointment and compound technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, plant raw materials, etc., can solve the limitation of compound Shangfuning ointment clinical application, rubber ointment is prone to pain, skin irritation and allergies To improve compatibility and affinity, reduce sensitization, and increase transdermal absorption

Active Publication Date: 2013-05-22
GUIZHOU JINQIAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern pharmacological studies have proved that Compound Shangfuning Ointment has the effects of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, and has definite curative effect on limb pain caused by various traumatic injuries. The existing method of producing Compound Shangfuning Ointment generally uses pharmaceutical The method on the standard (WS-10989 (ZD-0989)-2002), the preparation recorded in the above standard is a rubber plaster, the rubber plaster made by the above method is easy to cause pain when peeled off, and has certain irritation and allergies to the skin Sex, especially for patients with wounds can not be used, the above shortcomings limit the clinical application of compound Shangfuning ointment

Method used

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  • Compound trauma cream and preparation method thereof
  • Compound trauma cream and preparation method thereof
  • Compound trauma cream and preparation method thereof

Examples

Experimental program
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Embodiment 1

[0122] Prescription: 737g Touguxiang, 737g Red Hemp, 592g Feilongzhangxue, 737g Auspicious Grass, 592g Sorrel Grass, 444g White Dragon’s Beard, 737g Polygonum cuspidatum, 737g Panax notoginseng, 148g methyl salicylate, 96g camphor, borneol 163g, menthol 126g, glycerin 7600g, sodium polyacrylate 1200g, sodium carboxymethylcellulose 400g, gelatin 600g, sodium carbonate 100g, purified water 6000g.

[0123] Process:

[0124] ① Grind Touguxiang, Honghema, Feilongzhangxue, Auspicious Grass, Sorrelwort, White Dragon’s Beard, Polygonum cuspidatum and Panax notoginseng into coarse powder, extract twice with 90% ethanol for 1.5 hours each time, filter, Ethanol is recovered from the filtrate under reduced pressure and concentrated to an extract with a relative density of 1.28 at 40°C;

[0125] ② Grind borneol, menthol, and camphor and mix with methyl salicylate, and stir well;

[0126] ③ mix the solution of step ② with the extract of step ①;

[0127] ④Pour the sodium carbonate into pu...

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Abstract

The invention discloses a compound trauma cream. The compound trauma cream is cataplasmata which is prepared from murraya paniculata, largespike woodnettle root, toddalia, pink reineckea herb, oxalidaceae, alangium chinense harms, giant knotweed, pseudo-ginseng, methyl salicylate, camphor, borneol, menthol, glycerin, polyacrylate sodium, sodium carboxymethyl cellulose, glutin, sodium carbonate and pure water. According to the compound trauma cream and the preparation method thereof disclosed by the invention, a water-soluble high-molecular compound is used as a substrate and refined with the traditional Chinese medicine extract to form the cataplasmata; the cataplasmata not only can improve the compatibility and the affinity of the medicine and the skin and can improve the transdermal absorbing capacity, but also is large in drug loading capacity, high in bioavailability, long in moisture preserving period, strong in perspiration resistance, capable of being repeatedly pasted, small in thrill and not capable of causing skin allergy.

Description

technical field [0001] The invention relates to a compound Shangfuning ointment and a preparation method thereof, belonging to the field of medicine technology. Background technique [0002] Bruises seem to be a common occurrence for some people in daily life. Traditional Chinese medicine has a history of thousands of years in treating bruises. The ancient name "bruises" is a summary of all injuries. Most of them are caused by external forces or incorrect posture. caused by excessive force. In traditional Chinese medicine, injuries to muscles and bones, blood stasis, swelling and pain, disharmony of Qi and blood, blockage of meridians and even damage to organs caused by external forces acting on the human body are collectively referred to as bruises. Its main pathology is congestion and stagnation, blood stagnation and air resistance, so pain and swelling are the main manifestations. Treatment is mostly based on promoting blood circulation and dredging collaterals, relaxin...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/70A61P29/00A61K31/618A61K31/125A61K31/045
Inventor 张芝庭张涛涛
Owner GUIZHOU JINQIAO PHARMA
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