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Bone collagen high calcium tablet

A technology of bone collagen and bone collagen, applied in bone diseases, active ingredients of aluminum/calcium/magnesium, metabolic diseases, etc., can solve the problems of calcium deposition and low calcium absorption efficiency of bones, and achieve the goal of promoting proliferation and increasing bone density Effect

Active Publication Date: 2014-08-13
SIRIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention provides a kind of skeletal bone preparation that overcomes the problems of low calcium absorption efficiency and easy occurrence of calcium deposition in simple calcium supplement preparations, and uses calcium carbonate and bone collagen together to supplement calcium, fix calcium, and prevent calcium loss. Collagen High Calcium Tablets

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The raw material formula of the present embodiment is made up of each component of following parts by weight:

[0035] 40 parts of calcium carbonate, 18 parts of bone collagen, 1 part of coating powder, 0.08 part of vitamin D3, 3 parts of maltodextrin, 1 part of microcrystalline cellulose, 0.5 part of hydroxypropyl methylcellulose, cross-linked carboxymethyl cellulose 0.5 part of plain sodium, 0.5 part of sodium carboxymethyl starch, 0.1 part of silicon dioxide, and 0.1 part of magnesium stearate.

Embodiment 2

[0037] The raw material formula of the present embodiment is made up of each component of following parts by weight:

[0038] 41 parts of calcium carbonate, 19 parts of bone collagen, 2 parts of coating powder, 0.10 parts of vitamin D3, 4 parts of maltodextrin, 2 parts of microcrystalline cellulose, 0.4 parts of hydroxypropyl methylcellulose, cross-linked carboxymethyl cellulose 1.0 parts of plain sodium, 1.0 parts of sodium carboxymethyl starch, 0.5 parts of silicon dioxide, and 0.5 parts of magnesium stearate.

Embodiment 3

[0040] The raw material formula of the present embodiment is made up of each component of following parts by weight:

[0041] 42 parts of calcium carbonate, 20 parts of bone collagen, 2.5 parts of coating powder, 0.15 parts of vitamin D3, 5.5 parts of maltodextrin, 4.5 parts of microcrystalline cellulose, 1.25 parts of hydroxypropyl methylcellulose, cross-linked carboxymethyl 1.25 parts of sodium cellulose, 1.25 parts of sodium carboxymethyl starch, 1.0 parts of silicon dioxide, and 1.0 parts of magnesium stearate.

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Abstract

The invention discloses a bone collagen high calcium tablet. The bone collagen high calcium tablet is composed of the components, by weight, 40-45 parts of calcium carbonate, 18-24 parts of bone collagen albumen, 1-4 parts of coating powder, 0.08-0.25 part of vitamin D3, 3-8 parts of maltodextrin, 1-8 parts of microcrystalline cellulose, 0.5-2 parts of hydroxypropyl methyl cellulose, 0.5-2 parts of croscarmellose sodium, 0.5-2 parts of sodium carboxymethyl starch, 0.1-2 parts of silicon dioxide and 0.1-2 parts of magnesium stearate. The bone collagen albumen in the bone collagen high calcium tablet can enable calcium salt to be sufficiently absorbed by sclerotin, under the condition that the bone collagen albumen serves as a carrier, the calcium salt participates in the constitution of a bone and enables bone tissue to have toughness, proliferation of osteoblast is promoted, and bone mineral density is increased. The vitamin D3 is added to improve absorption of calcium and phosphorous by a human body, and standards of plasma calcium and plasma phosphorous are enabled to achieve degree of saturation.

Description

technical field [0001] The invention relates to a calcium tablet, in particular to a bone collagen high-calcium tablet. Background technique [0002] Osteoporosis is a systemic bone disease that occurs more frequently in postmenopausal women and older men, and now it tends to be younger. The eating habits of Chinese residents are also likely to lead to insufficient calcium intake, and with the increase of the elderly population in my country, the incidence of osteoporosis is also becoming more and more serious. Osteoporosis is a health concern in my country and the world. question. [0003] Studies have found that: bone is a complex organism composed of bone matrix and bone mineral, bone matrix is ​​collagen and collagen, accounting for 1 / 3 of bone, bone mineral is calcium hydroxyphosphate and a small part of hydroxymagnesium phosphate, accounting for 2 / 3. The formation of bones is firstly the human body absorbs small molecule collagen to synthesize collagen. C...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/39A61K9/28A61P3/02A61P19/10A61K33/10A61K31/593
Inventor 陈琼李健永沈建能
Owner SIRIO PHARMA CO LTD
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