Combined inactivate vaccine for haemophilus parasuis disease and streptococcus suis disease and preparation method for same

A technology of haemophilus porcine disease and double inactivated vaccine, which is applied in the direction of antibacterial drugs, pharmaceutical formulas, bacterial antigen components, etc., can solve the problem of inability to know whether the antigen inactivation is complete, large vaccine side effects, inflammation or swelling And other issues
CN103157101AActive Publication Date: 2013-06-19PU LIKE BIO ENG
4 Cites 6 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
PU LIKE BIO ENG
Publication Date
2013-06-19

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a combined inactivate vaccine for haemophilus parasuis disease and streptococcus suis disease and a preparation method for the same. The vaccine is prepared from inactivated haemophilus parasuis serotype-4 JS strain, haemophilus parasuis serotype-5 ZJ strain, streptococcus suis serotype-2 colony-R SC strain and streptococcus suis colony-C streptococcus equisubsp zooepidemius which are used as antigens, and adjuvants which are acceptable in veterinary medicine, and capable of performing immunoprophylaxis on the haemophilus parasuis disease caused by haemophilus parasuis, the streptococcus suis disease caused by streptococcus suis, and the mixed infection of haemophilus parasuis and streptococcus suis simultaneously. The vaccine is low in side effects, free from endotoxin and impure proteins in serum, good in immune safety, capable of achieving the effect of preventing multiple diseases by one injection in clinical and thus reducing cost, and capable of meeting the requirements of different users.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the technical field of animal biopharmaceuticals, in particular to a dual inactivated vaccine of Haemophilus parasuis and Streptococcus suis and a preparation method thereof. Background technique

[0002] Haemophilus parasuis and Streptococcus suis are the two most important bacterial infectious diseases in pig herds in my country. Haemophilus parasuis disease is multiple serositis and arthritis of pigs caused by Haemophilus parasuis (Hps), which is also known as Glsser's Disease. Haemophilus parasuis can affect young pigs from 2 weeks to 4 months, mainly in post-weaning and nursery stages, usually seen in pigs aged 5 to 8 weeks, the incidence rate can reach 40%, and the mortality rate can reach 50% %. The main clinical symptoms were cough, dyspnea, emaciation, lameness, and rough coat; the main necropsy lesions were fibrinous pleurisy, pericarditis, peritonitis, arthritis, and meningitis. In addition, Haemophilus parasuis c...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More