Composite silica gel protective dressing and preparation method thereof

A technology of silica gel and silica sol, which is applied in medical science, bandages, absorbent pads, etc., can solve the problems of large economic pressure on enterprises and patients, high product costs, etc., and achieve the effect of convenient use

Active Publication Date: 2013-07-10
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the current technical research has introduced silver ions and other metal ions with antibacterial function into the silica gel to increase the antibacterial function of scar removal products, the cost of the product prepared by this method is relatively high, which brings great harm to enterprises and patients. greater economic pressure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1: Add 5g of lysine and 2g of tea polyphenols into 1kg of deionized water to dissolve, stir evenly to make a mixed solution of lysine and tea polyphenols, add 200mL of silica sol to the above mixed solution under stirring After dissolving 0.001g of cationic surfactant polyacrylamide in 10mL of deionized water, it was added to the mixed solution of silica sol, lysine and tea polyphenols, so that the silica sol, lysine and tea polyphenols were evenly mixed, Obtain the composite silica gel, then centrifuge and dehydrate, and thoroughly clean the filter cake with deionized water, and then pulverize to obtain the composite silica gel powder, which is added to distilled water with a powder mass ratio of 1.5:1 in the powder. Heating and mixing at a temperature of 40° C. in a stirring state to obtain a composite silicone gel wound-protecting dressing. The composite silicone gel wound dressing was made into a patch according to the conventional process, and it was used f...

Embodiment 2

[0020] Example 2: 100g of lysine and 30g of tea polyphenols were added to 1kg of deionized water for dissolution to make a mixed solution of lysine and tea polyphenols, and 200mL of silica sol was added to the above mixed solution under stirring, and the After 0.003g zwitterionic surfactant cetyl dimethyl betaine was dissolved in 10mL deionized water, it was added to the mixed solution of silica sol, lysine and tea polyphenols to make silica sol and lysine Mix evenly with tea polyphenols to obtain a composite silica gel, then centrifuge and dehydrate, and thoroughly wash the filter cake with deionized water, and then pulverize to obtain a composite silica gel powder, which is added to the powder with a mass ratio of 1.5 : 1 in distilled water, heated and mixed at a temperature of 60°C in a stirring state to obtain a composite silicone gel wound dressing. The composite silicone gel wound dressing was made into a patch according to the conventional process, and it was used for t...

Embodiment 3

[0021] Example 3: 50g of lysine and 15g of tea polyphenols were added to 1kg of deionized water for dissolution to make a mixed solution of lysine and tea polyphenols, and 200mL of silica sol was added to the above mixed solution under stirring, and the After 0.003g of anionic surfactant sodium dodecyl sulfonate is dissolved in 10mL of deionized water, it is added to the mixed solution of silica sol, lysine and tea polyphenols, and the silica sol, lysine and tea polyphenols are mixed Uniformly obtain composite silica gel, then centrifuge and dehydrate, and thoroughly wash the filter cake with deionized water, and then pulverize to obtain composite silica gel powder. Add the powder into distilled water with a mass ratio of 1.5:1 to the powder, heat and mix evenly at 50°C in a stirring state to obtain a composite silicone gel wound dressing. The composite silicone gel wound dressing was made into a patch according to the conventional process, and it was used for trial in patient...

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PUM

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Abstract

The invention relates to medical composite silica gel protective dressing and a preparation method thereof. The method comprises the concrete steps of 1) adding lysine and tea polyphenol to deionized water to dissolve according to a certain ratio, evenly agitating to prepare mixed solution of lysine and tea polyphenol; 2) adding silica sol to the mixed solution of lysine and tea polyphenol; 3) adding a certain amount of surfactant to the mixed solution of lysine and tea polyphenol to evenly mix, thereby obtaining the composite silica gel; and 4) centrifuging and dewatering the composite silica gel, and thoroughly cleaning a filter cake by the deionized water, and crushing to obtain the composite silica gel powder, adding the powder to distilled water of which the mass ratio to the powder is 1.5 to 1, and evenly heating and mixing at the temperature of 40-60 DEG C to obtain the composite silica gel protective dressing under an agitation state, and preparing the composite silica gel protective dressing into a patch according to a common technology. The prepared protective dressing can effectively prevent bacterium and sterilize the wound surface, so as to relieve itching of the wound surface when effectively preventing and treating various scars after operations, trauma and burn. Thus, use of a receptor is greatly facilitated.

Description

technical field [0001] The invention relates to a medical composite silicone gel wound-protecting dressing and a preparation method thereof, in particular to a silicone gel with antibacterial and anti-inflammatory functions, which can promote wound healing and scar removal, and a preparation method thereof. Background technique [0002] Visible skin wounds, such as those caused by injury or surgery, often result in scarring. Scarring results in reduced sense of touch, loss of flexibility and loss of range of motion in many cases. Scarring also leads to significant aesthetic problems, especially when on the face and hands. Skin wounds are also susceptible to infection, which is fairly common even with conventional dressings. Burn victims are particularly susceptible to infection and may be left with severe scarring as the wound heals. There is a need for methods of treating skin lesions that minimize or eliminate scarring. [0003] There are many scar removal products on ...

Claims

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Application Information

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IPC IPC(8): A61L15/26A61L15/44A61L15/42
Inventor 卢亢陈锦涛韦加娜王志鸿
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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