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Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique

A synthesis process, tartaric acid technology, applied in the field of medicine, can solve problems such as confusion, blurred vision, fatigue, etc., and achieve the effects of low side effects, high safety, and clear functional components

Inactive Publication Date: 2013-07-17
PORSE FINE CHEM
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, side effects such as insomnia, allergies, muscle pain, weakness, nausea, movement disorders, blurred vision, tiredness, confusion, delusions, etc.

Method used

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  • Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique
  • Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique
  • Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique

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Embodiment Construction

[0040] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0041] figure 1 Shows the flow chart of the steps of preparing novel chiral anti-anxiety drugs based on the separation and synthesis process of tartaric acid of the present invention. S1 uses isatoic anhydride as the starting material and pyridine as the solvent. Both are heated to reflux to make the isatin After the acid anhydride is ring-opened, carry out the condensation reaction of the amino group and the carboxyethyl ester with ethyl aminoacetate to generate intermediate 2. The effect of adding ethyl aminoacetate is to carry out the condensation reaction of the amino group and the carboxyethyl...

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Abstract

The invention relates to a novel chirality antianxiety medicine prepared on the basis of tartaric acid resolution and composition technique. The novel chirality antianxiety medicine includes a series of antianxiety medicines prepared by a plurality of chemical reactions like taking Isatin acid anhydride as an original raw material and pyridine as a solvent to perform amino and carboxyl ethyl ester condensation reaction with amino ethyl acetate after anhydride and pyridine being gone through heating reflux. The anxiety-treatment medicines has the advantages of accurate functional components, obvious curative effect, low side effect and high safety in long-time use.

Description

technical field [0001] The invention relates to the technical field of medicines, and more specifically relates to a novel chiral anti-anxiety medicine prepared based on a tartaric acid resolution synthesis process. Background technique [0002] Anxiety disorder, like depression, is a kind of mental system disease that seriously endangers people's quality of life, and its impact is more extensive than depression. The occurrence of anxiety disorders is obviously related to the accelerated pace of society and more intense competition. Therefore, with the development of society, the incidence of anxiety disorders is increasing. According to statistics, the incidence rate of anxiety disorder in the urban population of our country is about 1-2%, while in developed countries it is nearly 10%, and it is still showing an increasing trend. According to a new study by Decision Resources, there are currently more than 87 million anxiety patients in seven major pharmaceutical markets i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D487/06
Inventor 沈光梓郝忠言王海平王小川欧武交陈卫
Owner PORSE FINE CHEM