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Preparation method of medicine for promoting fracture healing

A technology of fracture healing and medicine, which is applied in the direction of drug combination, pharmaceutical formula, active ingredients of hydroxyl compounds, etc., and can solve problems such as the complexity of the healing process

Inactive Publication Date: 2013-07-24
徐涛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Fracture is a very common trauma with complex healing process, involving a series of different cellular activities. Although there are claims of natural healing, research has proved that there are many factors affecting the healing process

Method used

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  • Preparation method of medicine for promoting fracture healing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1, the weight ratio of raw materials: 6 parts of large thistle, 6 parts of rhubarb, 2 parts of cattail, 2 parts of ground beetle, 2 parts of Galla gall, 2 parts of silver thread grass root, 6 parts of dog seedling, 1 part of veratrum, 1 serving of borneol. The preparation method is as follows:

[0024] (1) Extract the roots of Puhuang and Yinxian grass by supercritical fluid extraction method to obtain volatile oil;

[0025] (2) Take veratrum and borneol, crush them, and pass through a 200-mesh sieve to obtain superfine powder;

[0026] (3) Take large thistle, rhubarb, ground beetle, gallnut, dog seedling, add water to decoct for 1 hour, then filter, add water to filter residue, add water to decoct for 1 hour, then filter, combine the two filtrates, concentrate at 80°C to a relative density of 1.1, and obtain water extract;

[0027] (4) Add the volatile oil obtained in step 1 and the ultrafine powder obtained in step 2 to the water extract obtained in step 3,...

Embodiment 2

[0028] Example 2, the weight ratio of raw materials: 9 parts of large thistle, 9 parts of rhubarb, 4 parts of cattail, 4 parts of ground beetle, 4 parts of Galla gall, 4 parts of silver thread grass root, 9 parts of dog seedlings, 3 parts of veratrum, 3 servings of borneol. The preparation method is as follows:

[0029] (1) Extract the roots of Puhuang and Yinxian grass by supercritical fluid extraction method to obtain volatile oil;

[0030] (2) Take veratrum and borneol, crush them, and pass through a 200-mesh sieve to obtain superfine powder;

[0031] (3) Take large thistle, rhubarb, ground soft-shelled beetle, Galla chinensis, and dog vine, add water to decoct twice, filter, combine the filtrate, concentrate at 80°C to a relative density of 1.1, and obtain a water extract;

[0032] (4) Add the volatile oil obtained in step 1 and the ultrafine powder obtained in step 2 to the water extract obtained in step 3, stir evenly, and concentrate under reduced pressure at 60°C to ...

Embodiment 3

[0033] Example 3, the weight ratio of raw materials: 8 parts of thistle, 8 parts of rhubarb, 3 parts of cattail, 3 parts of ground beetle, 3 parts of Galla gall, 3 parts of silver thread grass root, 8 parts of dog seedlings, 2 parts of veratrum, 2 servings of borneol. The preparation method is as follows:

[0034] (1) Extract the roots of Puhuang and Yinxian grass by supercritical fluid extraction method to obtain volatile oil;

[0035] (2) Take veratrum and borneol, crush them, and pass through a 200-mesh sieve to obtain superfine powder;

[0036] (3) Take large thistle, rhubarb, ground soft-shelled beetle, Galla chinensis, and dog vine, add water to decoct twice, filter, combine the filtrate, concentrate at 80°C to a relative density of 1.1, and obtain a water extract;

[0037] (4) Add the volatile oil obtained in step 1 and the ultrafine powder obtained in step 2 to the water extract obtained in step 3, stir evenly, and concentrate under reduced pressure at 50°C to a rela...

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Abstract

The invention discloses a preparation method of a medicine for promoting fracture healing. The preparation method comprises the following steps of: adding pollen typhae, Japanese chloranthus root rhizome extraction volatile oil, black false hellebore and borneol ultrafine powder in a water extract of Circium japonicum, rheum officinale, Chinese Polyphaga, gallnut and Japanese calystegia; and uniformly stirring and decompressing and concentrating. Clinical experiments show that the medicine provided by the invention has the characteristics of good curative effect and high safety when used for promoting fracture healing and is worthy of clinically applying and popularizing.

Description

technical field [0001] The present invention is a branch case of an invention patent filed on February 17, 2012 with the title "A Drug for Promoting Fracture Healing and Its Preparation Method" and the application number is 201210036685.6. It relates to the field of traditional Chinese medicine, and specifically relates to drugs and its preparation method. Background technique [0002] With the development of my country's social economy, the national vehicle ownership rate has increased significantly, and various types of traumatic fractures are bound to increase year by year. Fracture is a very common trauma with a complex healing process, involving a series of different cellular activities. Although there is a saying of natural healing, studies have proved that there are many factors that affect the healing process. How to speed up the time of fracture healing, reduce the incidence of nonunion, and improve the quality of life of patients is an important issue facing traum...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P19/08A61P19/10A61K35/64A61K31/045
Inventor 王功国
Owner 徐涛
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