Aglae extract for lifting liver functions for the patients

A liver function and extraction technology, which is applied in medical raw materials derived from algae, digestive system, food preparation, etc., can solve problems such as failure of liver surgery, achieve the effects of reducing liver cirrhosis, promoting liver regeneration, and rapid liver function

Inactive Publication Date: 2013-08-14
FAR EAST BIO TEC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

From the above 4 points, we can understand the safety requirements for successful liver resection. However, mos

Method used

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  • Aglae extract for lifting liver functions for the patients
  • Aglae extract for lifting liver functions for the patients
  • Aglae extract for lifting liver functions for the patients

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1: Effect of Spirulina Extract Preparation on Regeneration Ability of Residual Liver After Hepatectomy

[0051] Male Wistar rats were purchased from the Animal Center of National Taiwan University School of Medicine, 5-6 weeks old, and raised by the Animal Center of National Taiwan University School of Medicine. The purchased rats were divided into three groups, one is the control group: rats fed normally; the other is the liver cirrhosis induced group: the drinking water containing 100ppm carcinogen diethylnitrosamine (diethylnitrosamine, DEN) for 9 weeks, but not Spirulina extract preparation was given; the third was the treatment group of cyanobacteria extract preparation: in addition to feeding drinking water containing DEN for 9 weeks, the cyanobacteria extract preparation 1g / kg was also fed every day from the 4th week for a total of 6 weeks (4th to 9th week). week).

[0052] (1) Quantification of liver regeneration volume change

[0053] The animals in t...

Embodiment 2

[0085] Example 2: Effect of Spirulina Extract Preparation on Fat Accumulation

[0086] Before liver surgery, it is necessary to check whether the patient is eligible for surgery. This condition can be determined by liver function. Liver function testing also includes the degree of fatty liver. The detection method used by the human body is to detect the softness of liver tissue to judge The degree of fatty liver, in this experiment, directly detects the fat content in the liver tissue. Therefore, in Example 2, the rat model with both hyperlipidemia and fatty liver was used to explore the effect of the cyanobacteria extract preparation on improving fatty liver, so as to understand the possibility of the cyanobacteria extract preparation improving the success rate of liver resection.

[0087] Male Wistar rats, 5-6 weeks old, were purchased from the Animal Center of National Taiwan University School of Medicine and raised by the Animal Center of National Taiwan University School ...

Embodiment 3

[0094] Example 3: Effect of Spirulina Extract Preparation on Liver Biochemical Index

[0095] (1) Spirulina extract preparation improves the degree of liver cirrhosis

[0096] Male Wistar rats were purchased from the Animal Center of National Taiwan University School of Medicine, 5-6 weeks old, and raised by the Animal Center of National Taiwan University School of Medicine. The purchased rats were divided into two groups, one was liver cirrhosis induction group: drinking water containing 100ppm carcinogen diethylnitrosamine (DEN) for 9 weeks, but no cyanobacteria extract preparation was given; the other was cyanobacteria extract Liquid preparation treatment group: In addition to being fed with drinking water containing DEN for 9 weeks, they were fed with blue-green algae extract liquid preparation every day from the 4th week, and the feeding doses were 2, 1, 0.8, 0.5 and 0.4 g / kg. A total of 6 weeks (weeks 4 to 9). Finally, the mice were sacrificed at the 12th week. After t...

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Abstract

The present invention discloses an Aglae extract for lifting liver functions for a patient, and the Aglae extract is prepared by extracting solution containing Aglae , and the Aglae extract comprises biologically active substances which are selected from one or more of allophycocyanin, sulfur-containing polysacarides, C-phycocyanin and the mixture thereof.

Description

technical field [0001] The invention relates to the application of an algae preparation, in particular to a cyanobacteria extract for improving the liver function of patients. Background technique [0002] Liver disease (liver disease) refers to a state in which liver cells are damaged due to infection, inflammation, injury, etc., resulting in insufficient overall liver function. There are many types of liver diseases, the most common being fatty liver, hepatitis, cirrhosis and liver cancer. Usually, liver disease, if it is not quite serious, often has no specific symptoms and signs. In addition, since the liver itself does not have pain-sensing nerves, only a little epidermis innervates pain-sensing, so when a lesion occurs inside the liver, if the surface has not been touched, no pain will be felt. Therefore, once the pain of liver disease occurs, the condition is already quite serious, and it is quite difficult to treat. [0003] The liver has more than 500 functions, ...

Claims

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Application Information

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IPC IPC(8): A61K36/02A23L1/29A23L2/38A61P1/16A23L33/00
Inventor 阙壮群黄凯文
Owner FAR EAST BIO TEC
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