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Preparation method of high-hardness cordyceps sinensis pure powder tablet

A technology of Cordyceps sinensis and pure powder tablets, which is applied in the field of medicine and health care products, can solve the problem of limited improvement of tablet hardness, and achieve the effect of long ingestion time, which is conducive to slow release and absorption

Active Publication Date: 2014-12-10
TONGHUA ZHENZUN BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when the water content reaches more than 35%, the improvement of the tablet hardness is very limited when the water content is increased.
This method of preparing Cordyceps pure powder tablets with higher hardness by increasing the water content of Cordyceps pure powder to more than 18% has not been reported so far

Method used

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  • Preparation method of high-hardness cordyceps sinensis pure powder tablet
  • Preparation method of high-hardness cordyceps sinensis pure powder tablet
  • Preparation method of high-hardness cordyceps sinensis pure powder tablet

Examples

Experimental program
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Effect test

Embodiment 1－16

[0020] (1) Harvest, clean and dry the Cordyceps sinensis medicinal material, then crush it into powder, add water and mix evenly, and control the moisture content of the medicinal material to be greater than 18-22%, perform direct compression of the powder, and dry the prepared tablet , that is.

[0021] (2) Collect, clean and dry the Cordyceps sinensis medicinal material, then crush it into powder, add water and mix it evenly, and control the moisture content of the medicinal material to 28-32%, perform direct compression of the powder, and dry the obtained tablet, Instantly.

[0022] (3) Collect, clean and dry the Cordyceps sinensis medicinal material, then crush it into powder, add water and mix evenly, and control the moisture content of the medicinal material to 38-42%, perform direct compression of the powder, and dry the obtained tablet, Instantly.

[0023] (4) Collect, wash and dry the Cordyceps sinensis medicinal materials, then crush them into powder, add water and...

experiment example

[0037] 1. Table 1 shows data such as process parameters for products pressed by powder direct compression method.

[0038]

[0039] 2. Table 2 shows the process parameters and other data of the product pressed by the powder direct compression method with the secondary tableting process including pre-compression.

[0040]

[0041] 3. Table 3 shows the process parameters and other data of products pressed by wet granulation and tabletting method.

[0042]

[0043] 4. Table 4 shows the process parameters and other data of the product pressed by the wet granulation tableting method with the secondary tableting process including pre-compression.

[0044]

[0045] see figure 1 , it can be seen that the moisture content of Cordyceps sinensis has a significant effect on tablet hardness. When the water content is lower than 8.0%, the tablet hardness is very low, not more than 2.0 kg. After the water content is higher than 10.0%, the tablet hardness is greatly improved, r...

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Abstract

The invention relates to a preparation method of a high-hardness cordyceps sinensis pure powder tablet, and belongs to the field of medicine and health care products. High water content cordyceps sinensis pure powder is used to be prepared into the tablet. Under the condition that no auxiliary material is added, the higher hardness cordyceps sinensis pure powder tablet is pressed by only taking cordyceps sinensis as a raw material. The method meets the requirement of modern people for 100% all natural products without additives, and particularly, for the cordyceps sinensis, a rare, famous and precious traditional Chinese medicinal material, a 100% all natural cordyceps sinensis product without the additives is more favored by the modern people. In addition, the high hardness cordyceps sinensis pure powder tablet can better meet various packaging and transportation conditions, and is free from phenomena such as fragments, powder falling, or chipping. Particularly, during sublingual administration, the sublingual administration time of the high hardness cordyceps sinensis pure powder tablet is longer, and the slow release and absorption of active ingredients of the cordyceps sinensis are more facilitated. The method has important practical application values in the fields of pharmaceutics and traditional Chinese medicinal material resource utilization.

Description

technical field [0001] The invention belongs to the field of medicine and health products, and relates to a method for processing Chinese medicinal materials, that is, a method for preparing high-hardness pure powder tablets of Cordyceps sinensis. Background technique [0002] Raw material powders of Chinese herbal medicines often contain more fiber components and oily components, which is unfavorable for the compression of Chinese herbal medicine powders, so the compression formability of Chinese herbal medicine powders is often not ideal, and it is difficult to obtain ideal hardness. Therefore, when preparing traditional Chinese medicine tablets, preparation workers often add a large amount of auxiliary materials in the prescription to improve the compressibility of the raw material powder of Chinese medicinal materials. Although the formability of traditional Chinese medicine tablets added with excipients or binders and other auxiliary materials has been improved and reac...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/068A61K9/20
Inventor 刘峰车鑫张欣
Owner TONGHUA ZHENZUN BIOLOGICAL SCI & TECH