Yinhuang medicine for clearing away lung-heat and preparation method thereof

A silver-yellow lung-clearing and drug technology, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of high production cost, long period, prolonged healing period of chronic bronchitis, etc., achieve good curative effect and increase the content of Effect

Active Publication Date: 2013-09-04
湖南安邦制药股份有限公司
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AI Technical Summary

Problems solved by technology

[0003] At present, the commercially available drugs for the treatment of chronic bronchitis have unsatisfactory effects in relieving cough, resolving phlegm and calming asthma, etc., which prolongs the cure period of chronic bronchitis, and the existing pharmaceutical technology has a long cycle and high production cost. Therefore, it is urgent to There is a need for an alternative product with short preparation cycle and good therapeutic effect

Method used

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  • Yinhuang medicine for clearing away lung-heat and preparation method thereof
  • Yinhuang medicine for clearing away lung-heat and preparation method thereof
  • Yinhuang medicine for clearing away lung-heat and preparation method thereof

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preparation example Construction

[0017] Due to the poor curative effect of the chronic bronchitis medicine prepared by the existing technology and the long preparation period, in order to solve the above problems, the present invention provides a preparation method of Yinhuang Qingfei medicine, which includes the following steps: S1, taking ephedra or roasting Ephedra is pulverized to obtain ephedra powder or roasted ephedra powder for later use; S2, using steam distillation to extract volatile oil from Citrus aurantium, loquat leaves and Shichangpu to obtain volatile oil, extract and extraction residue; use clathrate technology to extract volatile oil Inclusion to obtain clathrate; S3, using dynamic continuous extraction process to extract Tinglizi, bitter almond, fritillary fritillaria and Schisandra chinensis, to obtain alcohol extract and residue; concentrate the alcohol extract to obtain alcohol extract ; S4. Mix the extraction residue, alcohol extraction residue, Folium Isatidis Folium, Pangosia chinensi...

Embodiment approach

[0027] In addition, in addition to the advantages of the preparation process, the composition itself of the present application also has advantages. According to a typical embodiment of the present invention, in parts by weight, the raw material of the Yinhuang lung-clearing drug includes the following components: 55-65 parts of Tinglizi; 35-40 parts of ephedra or roasted ephedra; 40 parts of bitter almond ~50 parts of Fritillaria 40~50 parts; loquat leaves 40~50 parts; Daqingye 27~32 parts; Shichangpu 40~50 parts; 50 parts; 12-18 parts of schisandra; 12-18 parts of Citrus aurantium; 55-65 parts of raw gypsum; 12-18 parts of licorice.

[0028] Using the above raw material formula, the prepared Yinhuang Qingfei drug has a good therapeutic effect. Among the traditional Chinese medicine ingredients, Fritillaria, loquat leaves, Shichangpu relieve cough and reduce phlegm, ephedra relieves lung and relieves asthma, raw gypsum clears lung heat, Daqingye clears away heat and detoxifi...

Embodiment 1

[0035] 1) The raw materials are as follows: Tinglizi 60g; Ephedra 37.5g; Bitter almond 45g; Fritillaria 45g; Loquat leaves 45g; ; Citrus aurantium 15g; Gypsum 60g; Licorice 15g.

[0036] 2) Weigh the above-mentioned fourteen traditional Chinese medicines according to the formula, and grind the ephedra into ephedra powder with a particle size of 125 μm, and set aside. Put Citrus citrus Fructus Fructus, loquat leaves and Shichangpu into the first extraction tank, add 5 times the amount of water, and co-distill for 6 hours to obtain the volatile oil extract and extraction residue; use β-cyclodextrin at 40 ° C to extract The clathrate was carried out for 2 hours, and dried at 60° C. for 2 hours to obtain the clathrate.

[0037] 3) Mix Tinglizi, bitter almond, Fritillaria and Schisandra to obtain a mixture; add 7 times the amount of ethanol with a mass concentration of 70% to the mixture, turn on the steam to heat and reflux, turn on the dynamic pump to start pressurization, and u...

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Abstract

The invention discloses a Yinhuang medicine for clearing away the lung-heat and a preparation method thereof. The preparation method comprises the steps as follows: step one, ephedra or fried ephedra is smashed to obtain ephedra or fried ephedra powder; step two, a steam distillation method is used for extracting fructus aurantii immaturus, folium eriobotryae and rhizoma acori graminei to obtain essential oil, an extracting solution and extracting slag; and the essential oil is clathrated to obtain a clathrate compound; step three, semen lepidii, semen armeniacae amarae, thunberg fritillary bulb and schisandra chinensis are dynamically and continuously extracted to obtain an alcohol extracting liquid and alcohol extracting slag; the alcohol extracting liquid is concentrated to obtain alcohol extracting paste; step four, the extracting slag, the alcohol extracting slag, folium isatidis, dioscorea nipponica makino, artemisia rupestris, ginkgo leaves, gypsum and liquorice are mixed and added with water for decoction, and the extracting liquid is added for concentration to obtain a mixed medicine liquid concentration paste; step five, the alcohol extracting paste and the mixed medicine liquid concentration paste are mixed, dried by spraying and smashed to obtain mixed dry paste powder; and step six, ephedra or fried ephedra powder, the clathrate compound and mixed dry paste powder are mixed to obtain the Yinhuang medicine for clearing away the lung-heat. The Yinhuang medicine for clearing away the lung-heat has good effects on clearing lung, eliminating phlegm, and relieving cough and asthma.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a silver-yellow lung-clearing medicine and a preparation method thereof. Background technique [0002] Chronic bronchitis is a clinically common and frequently-occurring disease, which can be caused by influenza and belongs to the category of cough in traditional Chinese medicine. Winter and spring are the peak seasons of its attack every year. The disease involves a wide range of regions and a large population base, but there is no obvious regional difference in the incidence rate in various regions, and it is more common in children, middle-aged and elderly people. According to statistics, chronic bronchitis has a relatively high incidence rate in the normal population, with an overall incidence rate of 3.0% to 6.6%, among which the incidence rate in people over 50 years old is 14.2% to 18.0%, and the incidence rate in children is 3%. The acute exacerba...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K47/40A61P11/00A61P11/10A61P11/14A61P11/06A61K33/06
Inventor 高尚
Owner 湖南安邦制药股份有限公司
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