Supercharge Your Innovation With Domain-Expert AI Agents!

Preparation method of ginkgo honey ring oral solid preparation

A technology of ginkgo biloba and honey ring, applied in the field of medicine, can solve the problems of poor dissolution, strong hygroscopicity and poor stability of pharmaceutical preparations

Active Publication Date: 2015-11-25
王立强
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even if new equipment is used to make solid particles, there are still problems such as poor dissolution of pharmaceutical preparations, strong hygroscopicity, and poor stability.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: the preparation of ginkgo honey ring capsule

[0030] Put 1000g of Armillaria Gastrodiae powder into a decoction bag, add 8000ml of water and decoct three times, 2 hours each time, combine the decoction liquid, filter, concentrate to a relative density of about 1.10-1.15, and collect the paste; the collected Add ethanol to the paste to make the liquid contain 70% alcohol, and let it stand for 12 hours; take the supernatant after alcohol precipitation, concentrate to a relative density of 1.15-1.20, add 300g of microcrystalline cellulose, granulate with 20 mesh, and reduce pressure at 60°C Dry for 4 hours, pulverize; add 30g ginkgo biloba extract, mix well; use 10% ethanol as wetting agent, granulate with 24 mesh, granulate with 30 mesh, air-dry at 60°C for 4 hours, add 1% magnesium stearate, Mix well and pour 1000 capsules.

Embodiment 2

[0031] Embodiment 2: the preparation of ginkgo honey ring tablet

[0032] Put 1000g of Armillaria Gastrodiae powder into a decoction bag, add 8000ml of water and decoct three times, 2 hours each time, combine the decoction liquid, filter, concentrate to a relative density of about 1.10-1.15, and collect the paste; the collected Add ethanol to the paste to make the liquid contain 70% alcohol, and let it stand for 12 hours; take the supernatant after alcohol precipitation, concentrate to a relative density of 1.15-1.20, add 300g of microcrystalline cellulose, granulate with 20 mesh, and reduce pressure at 60°C Dry for 4 hours, pulverize; add 30g of Ginkgo biloba extract, mix well; use 20% ethanol as wetting agent, granulate with 30 mesh, granulate with 30 mesh, air-dry at 60°C for 4 hours, add 1% magnesium stearate, Mix well and press into 1000 tablets.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of medicaments, and in particular relates to a preparation method for ginkgo biloba armillaria oral solid preparation. By the preparation method, a twice granulating technology is adopted, the defects in the prior art are overcome, qualified ginkgo biloba armillaria capsules or ginkgo biloba armillaria tablets can be produced without adding new equipment; moreover, the product has high dissolution rate and stability, is convenient to take and carry; and meanwhile, the cost of production, transportation and storage is obviously reduced.

Description

Technical field: [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of ginkgo honey ring oral solid preparation. Background technique: [0002] The prior art discloses that the Ginkgo Honey Ring Oral Liquid produced by Chengdu Tianyin Pharmaceutical Co., Ltd. went on the market in 2001. Its indications are mainly used for coronary heart disease, angina pectoris, and ischemic cerebrovascular disease, which can improve heart and brain ischemia. Sexual symptoms, its ingredients are ginkgo biloba extract, honey ring powder. In 2003, the national standard of drug standard, chemical drug standard and local standard rose to the national standard, volume 16, compiled by the State Pharmacopoeia Commission, page 171, which disclosed the quality standard of Ginkgo honey ring oral liquid, and its prescription was Ginkgo biloba extract 3g, honey ring powder Add appropriate amount of water to 100g to make 1000ml. On April 3...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/16A61P9/10
Inventor 王立强
Owner 王立强
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com