Xuesaitong tablet containing eucommia extract and panax notoginseng saponins and application thereof

A technology of Panax notoginseng saponins and extracts, which is applied in the field of pharmaceutical compositions derived from Chinese herbal medicines, can solve problems such as unseen research, and achieve low cost, uniform content, and good stability

Active Publication Date: 2013-10-23
HUNAN XIANGYA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, it is found that the skin and leaves of Eucommia ulmoides contain antihypertensive ingredients, which also have good effects on cardiovascular and cerebrovascular diseases. However, using the interaction betwee

Method used

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  • Xuesaitong tablet containing eucommia extract and panax notoginseng saponins and application thereof
  • Xuesaitong tablet containing eucommia extract and panax notoginseng saponins and application thereof
  • Xuesaitong tablet containing eucommia extract and panax notoginseng saponins and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0022] Example 1:

[0023] Weigh 60 g of Panax notoginseng saponins, 10 g of Eucommia ulmoides extract, 9 g of crospovidone, 229.5 g of dextrin, and 1.5 g of magnesium stearate.

[0024] See figure 1 The process. After mixing the total saponins of Panax notoginseng, eucommia extract, magnesium stearate, and crospovidone, add dextrin to granulate, mix, and compress into 1000 tablets, which are coated with gastric-soluble film coating powder, aluminum Available in plastic-aluminum bath packaging (inner packaging).

Example Embodiment

[0025] Example 2:

[0026] Weigh 15g of Panax notoginseng saponins, 5g of Eucommia ulmoides extract, 9g of crospovidone, 220g of dextrin, and 1.5g of magnesium stearate. According to the method of Example 1, tablets were prepared.

Example Embodiment

[0027] Example 3:

[0028] Weigh 30 g of Panax notoginseng saponins, 5 g of Eucommia ulmoides extract, 8 g of crospovidone, 210 g of dextrin, and 1.5 g of magnesium stearate. According to the method of Example 1, tablets were prepared.

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Abstract

The invention belongs to the field of medicine compositions and provides a novel xuesaitong tablet. The novel xuesaitong table comprises the following effective ingredients in parts by weight: 1-10 parts of eucommia extract and 1-30 parts of panax notoginseng saponins. The novel xuesaitong tablet composition also comprises 100-500 parts by weight of pharmaceutically acceptable auxiliary, wherein the auxiliary comprises one or more of a disintegrating agent, a stabilizer, an excipient, a lubricating agent and a binding agent. According to the novel xuesaitong tablet, a xuesaitong tablet and eucommia extract with a depressing effect are jointly made into a preparation, multiple active ingredients and immunity enhancing effect of eucommia are combined, the defect that the original xuesaitong has a single medicinal property is overcome, and the novel xuesaitong tablet has a good effect on treatment of diseases such as hypertension, dizziness, brain pathway stasis obstruction, hemiplegia, physique softness, heart vessel stasis obstruction, chest stuffiness and pains, cerebrovascular disease sequela and coronary atherosclerotic hearth disease.

Description

technical field [0001] The invention belongs to the field of pharmaceutical compositions, in particular to a pharmaceutical composition derived from Chinese herbal medicines. Background technique [0002] Xuesaitong tablet is an existing relatively mature cardiovascular and cerebrovascular drug. Its main component is Panax notoginseng glycosides, which are total saponins processed from the main root or rhizome of Panax notoginseng (Burk) F.H.Chen, an Araliaceae plant. Excavated before flowering in autumn, mainly distributed in Yunnan, Guangxi and other provinces. The standard preparation method is as follows: take notoginseng and grind it into coarse powder, extract it with 70% ethanol, filter, concentrate the filtrate under reduced pressure, filter, and pass through a styrene-type non-polar or weakly polar copolymer macroporous adsorption resin column , washed with water, discarded the washing solution, eluted with 80% ethanol, concentrated the eluent under reduced pressur...

Claims

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Application Information

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IPC IPC(8): A61K36/46A61P9/12A61P9/10A61P25/00
Inventor 陈爱春
Owner HUNAN XIANGYA PHARMA
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