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Chewable tables for oral cavities as well as preparation method and application thereof

A technology of chewable tablet and oral cavity, which is applied in the field of oral chewable tablet and its preparation, which can solve the problems of large packaging volume, ingestion of mouthwash, and high price, and achieve the effects of simple preparation method, oral health enhancement and convenient application

Inactive Publication Date: 2013-10-23
荆州市荆康生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these two types of products, especially mouthwash, are still consumed by high-end people, mainly foreign brands, such as Listerine, Colgate, Crest, Oral-B, etc., and the prices are generally high, which is difficult to meet the needs of ordinary people. , Mouthwash is a liquid form item, the packaging is bulky, and it is inconvenient to carry. It is often restricted when taking an airplane or other means of transportation; it is not convenient for multiple people to use without a distribution tool, and the mouthwash is generally required to be Continue to use mouthwash for a few minutes after rinsing, which can easily lead to accidental ingestion of mouthwash
Although chewing gum is easy to carry and easy to use, the remaining chewing gum after use is not easy to handle and affects the environment
In addition, most current oral care products use fluorine-containing compounds, such as sodium fluoride, to prevent dental caries; antibiotics, such as nitrofurazone, or cationic surfactants, such as pyridinium chloride, are used for antibacterial; Hydrogen oxide is used to bleach teeth; these chemicals have side effects, adverse reactions that affect the normal microenvironment of the oral cavity, and do not meet the modern people's pursuit of nature, natural and environmentally friendly consumption concepts. Natural products instead of synthetic compounds have become the requirements of the times

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The components and mass fractions of the oral chewable tablet of the present invention are as follows: drynaria total flavonoids is 0.5%, tea polyphenols is 10%, microcrystalline cellulose is 15%, sucrose is 20%, mannitol is 10%, Xylitol 22%, Menthol 3%, Peppermint Oil 3.5%, Sodium Lauryl Sulfate 2%, Sodium Cocoyl Glycinate 3%, Starch Slurry 10%, Magnesium Stearate 1 %.

[0022] Drynaria total flavonoids, tea polyphenols, microcrystalline cellulose, sucrose, mannitol, xylitol, menthol, peppermint oil, sodium lauryl sulfate, and sodium cocoyl glycinate were weighed according to the above-mentioned corresponding amounts Crush, pass through a 80-mesh sieve, mix, granulate with 10% starch slurry by mass fraction, dry, pass through a 16-mesh sieve for granulation, add magnesium stearate with a mass fraction of 1%, mix, compress into tablets, and pack. .

[0023] Take the prepared chewable tablet and put it in the mouth, chew slowly until the tablet turns into powder, rinse m...

Embodiment 2

[0026] The components and mass fractions of the oral chewable tablet of the present invention are as follows: drynaria total flavonoids is 1%, tea polyphenols is 15%, starch is 20%, sucrose is 5%, dextrin is 10%, and mannitol is 5%, Xylitol 10%, Glucose 5%, Citric Acid 3%, Aspartame 3%, Stevioside 2%, Sodium Saccharin 3%, Menthol 2%, Peppermint Oil 2% for sodium lauryl sulfate, 2% for alkylamide betaine, 8% for polyvinylpyrrolidone, and 2% for micronized silica gel.

[0027] Drynaria total flavonoids, tea polyphenols, starch, sucrose, dextrin, mannitol, xylitol, glucose, citric acid, aspartame, stevioside, sodium saccharin, menthol, peppermint oil, twelve Alkyl sodium sulfate and alkylamide betaine are weighed according to the above corresponding amounts, crushed, passed through a 80-mesh sieve, mixed, granulated with polyvinylpyrrolidone with a mass fraction of 8%, dried, passed through a 16-mesh sieve for granulation, and added mass Micropowder silica gel with a fraction of...

Embodiment 3

[0031] The components and mass fractions of the oral chewable tablet of the present invention are as follows: drynaria total flavonoids is 2%, tea polyphenols is 20%, sucrose is 15%, mannitol is 5%, sorbitol is 15%, xylose Alcohol 12%, Dextrose 3%, Citric Acid 5%, Sodium Saccharin 5%, Sodium Cocoyl Glycinate 3%, Starch Slurry 6%, Carboxymethylcellulose 6%, Stearic Acid Magnesium is 3%.

[0032] Drynaria total flavonoids, tea polyphenols, sucrose, mannitol, sorbitol, xylitol, glucose, citric acid, sodium saccharin, and sodium cocoyl glycinate were weighed according to the above corresponding amounts, crushed, and passed through a 80-mesh sieve , mix, be 6% starch slurry with mass fraction and mass fraction be 6% carboxymethyl cellulose granulate, dry, cross 16 mesh sieves and granulate, add the magnesium stearate that mass fraction is 3%, mix, Tabletting and packaging.

[0033] Take the prepared chewable tablet and put it in the mouth, chew slowly until the tablet turns into ...

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PUM

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Abstract

The invention discloses chewable tables for oral cavities as well as a preparation method and an application thereof. Each chewable table comprises 0.5%-20% of drynaria total flavonoids, 5-50% of tea polyphenol and the balance of pharmaceutically acceptable carrier in percentage by mass. The preparation method of the chewable tables comprises the following steps of: crushing, sieving, mixing, pelleting, drying, pressing and packaging the 0.5%-20% of drynaria total flavonoids, the 5-50% of tea polyphenol and the balance of filler, corrigent, wetting agent, binding agent and lubricating agent; and as for the application, the chewable tables for oral cavity nursing are put in a mouth and chewed, and then the mouth is rinsed with clear water. As the tea polyphenol has good health care and treatment effect on oral cavity inflammation and oropharynx inflammation and the drynaria total flavonoids has a promotion effect on the repair, regeneration and rebuilding of periodontium, the chewable tables can be used for promoting the health of the oral cavities by adding the drynaria total flavonoids and the tea polyphenol.

Description

technical field [0001] The invention relates to an oral chewable tablet, in particular to an oral chewable tablet and its preparation method and application. Background technique [0002] With the improvement of people's living standards, the pursuit of beauty and healthy life is constantly improving, and oral hygiene has become one of the focuses of modern people. The most common oral diseases are dental caries and periodontal disease. The average per capita caries rate in my country is 70%, while the prevalence rate of periodontal disease is as high as 90%. The World Health Organization has listed dental caries as one of the three major diseases that human beings must prevent and treat, and the health of periodontal tissue as one of the 10 criteria for human health. Oral health has also become an indicator to measure people's living standards, and oral health supplies have become a necessity for people's lives. [0003] The main oral hygiene products currently on the mar...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61K9/20A61P1/02A61P31/02
Inventor 王林
Owner 荆州市荆康生物科技有限公司
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