Trimetazidine hydrochloride sustained release tablet and preparation method thereof
A technology of trimetazidine hydrochloride and sustained-release tablets, which is applied in the direction of pharmaceutical formulas, medical preparations containing no active ingredients, and medical preparations containing active ingredients, etc., which can solve the problems of pain relief, curative effect and clinical application limitations, heart disease, etc. Function damage and other problems, to achieve the effect of improving compliance, avoiding sudden release phenomenon, and stable quality
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Embodiment 1
[0032] Prepare 1000 trimetazidine hydrochloride sustained-release tablets according to the prescription in the following table 1 and the above-mentioned preparation method.
[0033] Table 1 Prescription composition and dosage of trimetazidine hydrochloride sustained-release tablets (based on 1000 tablets)
[0034]
[0035] In the table, 8% povidone-80% ethanol-water solution obtains by following preparation method: be that in the ethanol aqueous solution of 80% that povidone is dissolved in mass concentration, the mass concentration that adjusts povidone is 8%, namely have to. Adhesives in the following examples were prepared using the same method.
Embodiment 2
[0037] Prepare 1000 trimetazidine hydrochloride sustained-release tablets according to the prescription in the following table 2 and the above-mentioned preparation method.
[0038] Table 2 Prescription composition and dosage of trimetazidine hydrochloride sustained-release tablets (based on 1000 tablets)
[0039]
Embodiment 3
[0041] Prepare 1000 trimetazidine hydrochloride sustained-release tablets according to the prescription in the following table 3 and the above-mentioned preparation method.
[0042] Table 3 Prescription composition and dosage of trimetazidine hydrochloride sustained-release tablets (based on 1000 tablets)
[0043]
[0044]
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