Negative-pressure liquid feeding device based on liquid core wave guide pipe

Abstract

The invention provides a negative-pressure liquid feeding device based on a liquid core wave guide pipe. The negative-pressure liquid feeding device comprises a liquid core wave guide pipe, a vacuum chamber, a vacuum pump, a left connector and a right connector, wherein the vacuum pump is communicated with an inner cavity of the vacuum chamber; a main body part of the liquid core wave guide pipe is arranged in the vacuum chamber; a sample feeding end and a detection end of the liquid core wave guide pipe stretch out of the vacuum chamber; the sample feeding end of the liquid core wave guide pipe is sleeved with a first sample feeding capillary pipeline; the first sample feeding capillary pipeline is connected with the left connector; the left connector is connected with a second sample feeding capillary pipeline for connecting a sample position; the second sample feeding capillary pipeline is provided with a left valve; the detection end of the liquid core wave guide pipe is sleeved with a first sample discharging capillary pipeline; the first sample discharging capillary pipeline is connected with the right connector; the right connector is connected with a second sample discharging capillary pipeline for connecting a waste discharging device; the second sample discharging capillary pipeline is provided with a right valve. The negative-pressure liquid feeding device based on the liquid core wave guide pipe can prevent a sample solution from being crossly polluted and has the advantages of small volume, low power consumption, easiness in modularization and small detection result error.

Description

technical field [0001] The present invention relates to a measuring instrument, in particular to a device or instrument for optical testing by optical means. Background technique [0002] Liquid-core waveguides have the characteristics of gas permeability, hydrophobicity, chemical inertness, and lower refractive index than water, and have been widely used in various fields such as absorbance detection, fluorescence detection, Raman spectroscopy, and gas sensors. However, due to its hydrophobicity, the liquid cannot be automatically introduced by capillary action, and external power is required to drive the liquid into the liquid core waveguide during application. At present, pressure-driven technology is mainly used to drive liquid into the liquid core waveguide, such as syringe pumps and gravity-driven systems. The change of the flow rate of the liquid can only be achieved by adjusting the liquid level difference. The operation accuracy is relatively high, and the reproduc...

AI Technical Summary

Problems solved by technology

However, due to its hydrophobicity, the liquid cannot be automatically introduced by capillary action, and external power is required to drive the liquid into the liquid core waveguide during application.

At present, pressure-driven technology is mainly used to drive liquid into the liquid core waveguide, such as syringe pumps and gravity-driven systems, but the syringe pump is large in size and expensive, which is not conducive to the miniaturization and integration of the liquid inlet device. The change of liquid flow rate can only be achieved by adjusting the liquid level difference. The operation accuracy is relatively high, and the reproducibility of the liquid intake is greatly affected by the ambient temperature and humidity.

The above commonly used liquid inlet systems also inevitably have the problem of being contaminated by the sample solution, which not only increases the cleaning operation, but also may cause cross-contamination between different samples, which affects the accuracy and reliability of the test.

At the same time, the traditional liquid inlet device cannot remove the bubbles contained in the liquid, and the bubbles entering the liquid core waveguide will cause different degrees of interference no matter in the process of total reflection of the optical path or in the process of liquid flow. The sample solution needs to be degassed in advance before it can enter the liquid core waveguide for detection, which greatly increases the complexity of the experimental operation, and is more likely to affect the detection results of the sample solution and cause errors

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