A kind of preparation method of extracting skin anti-inflammation, detumescence and antipruritic ointment from microalgae dregs

A technology for reducing swelling, relieving itching and microalgae meal, applied in the field of biomedicine, can solve problems such as no literature reports, and achieve the effects of stable drug effect, improved utilization rate, and significant social and economic benefits.

Active Publication Date: 2016-05-25
FUJIAN LANHAO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The use of microalgae meal extracts to treat skin diseases has not been reported in the literature so far

Method used

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  • A kind of preparation method of extracting skin anti-inflammation, detumescence and antipruritic ointment from microalgae dregs
  • A kind of preparation method of extracting skin anti-inflammation, detumescence and antipruritic ointment from microalgae dregs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Weigh 1 kg of Schizochytrium algae DHA (docosahexaenoic acid) oil scum, crush it into powder without granules; add 3 L of ethanol with a concentration of 95% warmed at 30 ° C, and stir evenly for 0.5 h, until the algal meal powder is dissolved; after cooling to room temperature, centrifuge at 4500rpm, centrifuge for 10min to separate the supernatant and precipitate, and take the supernatant; steam the supernatant in a water bath at 45°C, under the condition of a vacuum of 0.09MPa , evacuated for 1 hour, the solvent was removed and the fishy smell was removed; concentrated to viscous colloid, the skin anti-inflammatory, detumescence and antipruritic ointment of the present invention was obtained.

Embodiment 2

[0024] Weigh 1 kg of scutellaria chytridum DHA (docosahexaenoic acid) oil, crush it into powder without particles; add 4L of ethanol with a concentration of 95% warmed at 40°C, and stir evenly for 1 hour while adding until the algal meal powder is dissolved; after cooling to room temperature, centrifuge at 5000 rpm, centrifuge for 20 minutes to separate the supernatant and precipitate, and take the supernatant; steam the supernatant in a water bath at 46°C, and vacuum 0.095MPa. Vacuum for 1 hour to remove the solvent and remove the fishy smell; concentrate to a viscous paste to obtain the skin anti-inflammatory, detumescence, and antipruritic ointment of the present invention.

Embodiment 3

[0026] Weigh 1 kg of Cryptidinium koi's DHA (docosahexaenoic acid) oil scum, crush it into powder without granules; add 5 L of ethanol with a concentration of 95% warmed at 50 ° C, and stir evenly for 1.5 h, until the algal meal powder is dissolved; after cooling to room temperature, centrifuge at 6000rpm, centrifuge for 15min to separate the supernatant and precipitate, and take the supernatant; steam the supernatant in a water bath at 47°C, under the condition of a vacuum of 0.095MPa , evacuated for 1 hour to remove the solvent and remove the fishy smell; concentrate to viscous liquid to obtain the skin anti-inflammatory, detumescence and antipruritic ointment of the present invention.

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Abstract

The present invention specifically provides a preparation method for extracting skin anti-inflammatory, detumescence, and antipruritic ointment from microalgae dregs. The specific steps are as follows: use microalgae dregs produced from docosahexaenoic acid as raw materials, and first pulverize the microalgae dregs into powder, then add ethanol, stir evenly while adding, centrifuge after cooling to get the supernatant, heat the supernatant indirectly, concentrate in vacuum until viscous, and obtain the skin anti-inflammatory, swelling and antipruritic ointment extracted from the microalgae meal. The external skin ointment produced has antibacterial, antipruritic, anti-inflammatory and detumescent effects, and is suitable for local treatment of neurodermatitis, contact dermatitis, chronic eczema, insect bite dermatitis and itchy skin diseases. The production process is non-toxic, harmless and pollution-free. It turns the waste of algae dregs into medical products, which greatly increases the utilization rate of waste. Efficient application has significant social and economic benefits.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and more specifically relates to a preparation method and application of a skin anti-inflammation, swelling and antipruritic ointment extracted from microalgae dregs. Background technique [0002] Skin itching, redness, and inflammation are common skin diseases and one of the frequently-occurring diseases that seriously affect people's health. They are usually divided into neurodermatitis, contact dermatitis, chronic eczema, insect bite dermatitis, and itchy skin diseases. . Patients usually feel itching, pain, numbness, burning, etc. and cannot help scratching or rubbing, which can lead to skin scars and, in severe cases, skin cancer. Therefore, a non-toxic, non-hazardous and side-effect-free drug that can reduce inflammation, reduce swelling, and relieve itching is urgently desired by many patients, and the extract of microalgae meal has this excellent function. Microalgae such as Schizoc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/02A61K36/06A61K9/06A61P17/00A61P31/02
Inventor 李昊
Owner FUJIAN LANHAO BIOTECH
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