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Novel preparation method for pinellia stomach-harmonizing Chinese patent medicine

A technology of Chinese patent medicine and pinellia, which is applied in the field of new preparation of pinellia and stomach Chinese patent medicine, can solve the problems of insufficient extraction, complicated extraction process, difficult preparation, etc., and achieve less loss of active ingredients, high extraction purity, and compliance Good results

Active Publication Date: 2014-01-01
WUHAN FUXING BIOTECH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a novel preparation method of Pinellia and Stomach Chinese patent medicines, which is used to solve the difficulties in the preparation of existing Pinellia and Stomach Chinese patent medicines. The extraction and purification of active ingredients is difficult, the extraction is insufficient, and the loss of functional components is serious. , technical problems such as complex extraction process and low efficiency
[0007] At the same time, the present invention also solves the problems of many existing technological processes, long time, cumbersomeness and low efficiency, too many containers are needed, and it is too troublesome to turn them up and down.

Method used

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Effect test

Embodiment 1

[0030] Embodiment 1: a kind of novel preparation method of pinellia and stomach Chinese patent medicine, comprises the following steps:

[0031] A. Grind 3.5 parts of ginger pinellia (1kg each, the same below), 2.5 parts of Zhigancao, and 1.5 parts of Chinese jujube to 40 mesh fineness, put them into a microwave ultrasonic extraction kettle, and add 10 times the weight of the original medicine Heat the water in a water bath at 100°C for 1 hour, then add concentrated HCL to adjust the pH to 3-4, turn on the microwave, heat the agent to 95°C and keep it for 3 minutes, then add 40% sodium hydroxide to adjust the pH to 7 , then add 99% ethanol with a multiple of 20 times the weight of the original drug, turn on the ultrasonic generator, adjust the frequency of the ultrasonic generator to 20KHz, turn off the ultrasonic generator after working for 15 minutes, filter at last, get rid of the filter residue, and recover the ethanol under reduced pressure, Concentrate the remaining liqu...

Embodiment 2

[0036] Embodiment 2: a kind of novel preparation method of pinellia and stomach Chinese patent medicine, comprises the following steps:

[0037] A. Grind 4 parts of ginger Pinellia, 3 parts of Radix Glycyrrhizae, and 2 parts of Jujube into 40-mesh fineness pellets, put them into a microwave-type ultrasonic extraction kettle, add water 10 times the weight of the original drug, and heat in a water bath at 100°C 1 hour, then add concentrated HCL to adjust the pH value to 3-4, turn on the microwave, heat the drug to 95°C and keep it for 6.5 minutes, then add 40% sodium hydroxide, adjust the pH to 7, and then add the original drug in a weight multiple of 20 times of 99% ethanol, turn on the ultrasonic generator, adjust the frequency of the ultrasonic generator to 20KHz, turn off the ultrasonic generator after working for 15 minutes, and finally filter, remove the filter residue, recover the ethanol under reduced pressure, and concentrate the remaining liquid to 1.05-1.1 thick paste...

Embodiment 3

[0042] Embodiment 3: a kind of novel preparation method of pinellia and stomach Chinese patent medicine, comprises the following steps:

[0043] A. Grind 4.5 parts of ginger Pinellia, 3.5 parts of Radix Glycyrrhizae, and 2.5 parts of Jujube to 40-mesh fineness pellets, put them into a microwave-type ultrasonic extraction kettle, add water 10 times the weight of the original drug, and heat in a water bath at 100°C 1 hour, then add concentrated HCL to adjust the pH value to 3-4, turn on the microwave, heat the drug to 95°C and keep it for 10 minutes, then add 40% sodium hydroxide, adjust the pH to 7, and then add the original drug in a weight multiple of 20 times of 99% ethanol, turn on the ultrasonic generator, adjust the frequency of the ultrasonic generator to 20KHz, turn off the ultrasonic generator after working for 15 minutes, and finally filter, remove the filter residue, recover the ethanol under reduced pressure, and concentrate the remaining liquid to 1.05-1.1 thick pa...

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Abstract

The invention discloses a novel preparation method for a pinellia stomach-harmonizing Chinese patent medicine. The Chinese patent medicine is prepared by performing microwave heating and ultrasonic mixing on ginger processed pinellia, Baikal skullcap root, honey-fried licorice root, jujube, dried ginger, coptis and pilose asiabell root to extract active ingredients in the medicinal materials. The method radically overcomes the defect of low extraction rate of active ingredients extracted by common methods such as water extraction and ethanol extraction in most conventional Chinese medicines. The method avoids discomfort caused by decocting the Chinese medicaments, and can greatly extract the active ingredients of the medicaments such as baicalin, saponin and various trace elements particularly by organically combining the processes of microwave and ultrasonic mixing extraction and the like. Moreover, the extraction purity is high, the loss of the active ingredients is low, and the problem of preventing the active ingredients of the extracts from being volatilized in the industry is solved. The prepared medicine has a remarkable treatment effect, has the effects of soothing liver and regulating qi, harmonizing stomach and reducing heat, tonifying stomach and nourishing yin, harmonizing stomach and dispersing blood stasis, has good compliance, and is suitable for various stomach disease patients to administrate.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a novel preparation method of pinellia and stomach Chinese patent medicines. Background technique [0002] Chronic gastritis and peptic ulcer belong to the category of epigastric pain and fullness in traditional Chinese medicine. Common frequently-occurring disease in the world, protracted and difficult to heal. Traditional Chinese medicine believes that the stomach belongs to the heart, and it is the exterior and interior of the spleen. If there is permanence, the acquired foundation can be exercised. If typhoid fever is wrongly treated, the spleen and stomach are damaged, and the pathogenic heat is trapped; or the factor is deficiency of yang in the body, and the spleen and stomach are weak; coupled with improper diet, loss of work and rest, emotional discomfort, stagnation of phlegm and dampness, and dampness and heat. , all can lead to spleen and stomach dysfun...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/04
Inventor 邓才华
Owner WUHAN FUXING BIOTECH PHARMA
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