3 results about "Aqueous two-phase system" patented technology

This invention discloses a method for preparing multifunctional sensing hollow gel fibers based on an aqueous two-phase system. The technical solution is based on an aqueous two-phase system formed by polyvinyl alcohol (PVA) and dextran in water. Using a coaxial spinning process, a PVA solution is injected into the shell channel of a coaxial spinning device, and a dextran solution is injected into the core channel. Relying on the ultra-low tension between the two aqueous phase interfaces, the PVA solution and dextran solution after extrusion are kept in a parallel laminar flow state. After coagulation treatment, a core-shell structure gel fiber is obtained. Subsequently, it undergoes solvent evaporation treatment, water washing treatment, and eutectic solvent replacement to finally prepare the hollow gel fiber. The gel fiber of this invention possesses stretchability, compression resilience, high conductivity, and a wide operating temperature range. It can be made into multidimensional sensors and humidity sensors to monitor strain, direction, pressure, and humidity, exhibiting considerable sensitivity and stability.

The invention discloses a method for driving liquid drops to move in an aqueous two-phase system and application of the method, and the method comprises the following steps: dissolving polyethylene glycol and glucan in deionized water, centrifuging and standing for layering to respectively obtain a PEG solution and a DEX solution; a DEX solution is dropwise added to different positions of the PEG solution containing SDBS, and two DEX liquid drops are formed; dropwise adding a DEX solution containing calcium chloride between the two DEX liquid drops to form DEX liquid drops containing calcium chloride; the two DEX liquid drops can move towards the DEX liquid drop containing calcium chloride and are finally gathered together; or dropwise adding a DEX solution containing calcium chloride to different positions of the PEG solution containing SDBS to form two DEX liquid drops containing calcium chloride; the two DEX liquid drops containing calcium chloride can move towards each other and finally gather together. The method can break through the limitation of low interfacial tension of an aqueous two-phase system, realizes controllable movement of liquid drops, has biocompatibility, and can be used for conveying biochemical reagents and initiating an enzymatic reaction.

In a hydrogel preparation process, if a biological substance sensitive to external reaction is added, physical or chemical stimulation applied in a traditional hydrogel preparation method not only needs a complex process, but also possibly affects the activity and structure of particles in the hydrogel. On the other hand, according to the hydrogel utilizing the aqueous two-phase system and the preparation method of the hydrogel, provided by the invention, the formation of the hydrogel and the encapsulation of the target nanoparticles in the hydrogel can be realized at the same time. The present invention successfully and simply concentrates target nanoparticles in a hydrogel in a high yield. Furthermore, the present invention relates to a hydrogel using an aqueous two-phase system and a method for preparing the same, in which concentration and hydrogel formation are performed at the same time, thereby shortening the preparation time of the hydrogel and significantly reducing the cost, by promoting the synchronization of concentration and hydrogel, and to a method for preparing the hydrogel using the aqueous two-phase system.