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Preparation method of Chinese yam formula granules

A technology of formula granules and yam, which is applied in the field of yam formula granules and its preparation, can solve the problems of gelatinization on the surface of medicinal materials, unfavorable water penetration, and affecting the extraction effect, so as to increase solid-liquid phase contact, improve water penetration, and improve Effect of Dissolution Efficiency

Active Publication Date: 2014-02-26
培力(南宁)药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the yam decoction pieces are piled up in the extraction tank and soaked in cold water, because the yam slices are thick and contain a large amount of starch and other substances, the cold water cannot quickly and fully penetrate into the decoction pieces, and the penetration effect is poor; after soaking in cold water, decocting, Due to the rapid temperature rise, hot water fails to penetrate into the yam decoction pieces in time and completely, and the surface will quickly gelatinize due to excessive temperature, preventing further infiltration of water and affecting the extraction effect; The gelatinization of the surface of the medicinal material is also not conducive to water penetration; if the sliced ​​yam is too thin, it will be brittle during boiling, because it contains a large amount of starch, it is easy to gelatinize and coke during heating, and it is easy to block the pipeline during production and cannot filter the medicinal liquid; Therefore, the traditional extraction method often cannot be decocted thoroughly during decoction, the active ingredients cannot be extracted completely, the extraction efficiency of medicinal materials is low, and the resources of medicinal materials are wasted. Seriously affect the quality of the product
At present, there are no literature reports on the low-temperature dynamic circulation extraction method of related yam formula granules

Method used

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  • Preparation method of Chinese yam formula granules

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Experimental program
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Effect test

Embodiment 1

[0024] Take 300kg of Chinese yam, wash and process it, and slice it into slices with a thickness of 2-4mm; put it into the hanging basket of the extraction tank, add water 10 times the weight of the yam, and soak for 2 hours at 40°C; then use dynamic circulation extraction technology, under normal pressure Extract at 90°C for 4 hours, filter, concentrate the filtrate, add 25 kg of dextrin as an auxiliary material, mix well, spray dry, pulverize, add 0.1 kg of magnesium stearate, and granulate to obtain 100 kg of yam formula granules.

Embodiment 2

[0026] Take 500kg of Chinese yam, wash and process it, and slice it into slices with a thickness of 3-6mm; put it into the hanging basket of the extraction tank, add water 5 times the weight of the yam, soak at 50°C for 1.5 hours; then use dynamic circulation extraction technology, under normal pressure Extract at 95°C for 3 hours, filter, concentrate the filtrate, add 56 kg of maltodextrin as an auxiliary material, mix well, spray dry, pulverize, add 0.05 kg of magnesium stearate, and granulate to obtain 100 kg of yam formula granules.

Embodiment 3

[0028] Take 400kg of Chinese yam, wash and process it, and slice it with a thickness of 6-8mm; put it into the hanging basket of the extraction tank, add water 8 times the weight of the yam, and soak for 1 hour at 60°C; Extract at 97°C for 2 hours, filter, concentrate the filtrate, spray dry, add 38 kg of lactose as an auxiliary material, mix well, spray dry, pulverize, add 0.07 kg of magnesium stearate, and granulate to obtain 100 kg of yam formula granules.

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Abstract

The invention relates to Chinese yam formula granules. The Chinese yam formula granules comprise 3000 to 5000 parts by weight of Chinese yam medicinal slices, 250 to 640 parts by weight of dextrin, lactose, maltodextrin or composition of the dextrin, lactose and maltodextrin and 0.5 to 1.5 parts by weight of magnesium stearate. The preparation method comprises the following steps: washing and slicing the Chinese yam medicinal material used as a raw material, soaking the Chinese yam slices in warm water until the Chinese yam slices are thoroughly wetted, extracting the Chinese yam slices by adopting a dynamic circulation extraction method, combining the extract liquid, concentrating the extract liquid, drying the concentrated extract in an atomizing manner to obtain the Chinese yam extract, uniformly mixing the Chinese yam extract with auxiliary materials, and granulating the mixture to obtain the Chinese yam formula granules. Each gram of Chinese yam formula granules is equivalent to 3-5g of Chinese yam medicinal slices. The Chinese yam formula granules are convenient to eat, the quality is controllable, and the Chinese yam formula granules are easy to store and convenient to carry. According to the preparation method, the Chinese yam medicinal slices are soaked with the water at an appropriate temperature, so that the gelatinization on the surface of the medicinal slices can be effectively prevented, the effect for penetrating the medicinal material through the water can be improved, and the dissolution efficiency of active ingredients of the medicinal material can be improved by adopting the low-temperature forced dynamic circulation extracting technology.

Description

technical field [0001] The invention relates to a yam formula granule and a preparation method thereof, belonging to the technical field of preparation of traditional Chinese medicine formula granules. Background technique [0002] Yam is the tuber of Dioscor eaceae ( Dioscor eaceae ) plant Dioscorea opposita Thunb. . Yam is flat in nature and sweet in taste, and has the functions of nourishing the spleen and stomach, promoting body fluid and benefiting the lungs, and nourishing the kidney and astringent essence. It is not only a good medicine for invigorating the spleen and nourishing qi, but also a traditional health food. Yam is one of the earliest Chinese medicines listed in Materia Medica, and it is listed as top grade in "Shen Nong's Materia Medica". It can be used alone or in combination with other supplements or medicines. There are decoctions, powders, patent medicines, medicinal porridge and dishes, etc. It can strengthen the spleen, nourish the lungs, strengthen ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/16A61P1/14A61P1/12A61P11/14A61P15/00A61P13/00
Inventor 覃高能黄志权周永强林广史雪琦宋法阳
Owner 培力(南宁)药业有限公司
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