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External ointment for treating onychomycosis

A technology for ointment and onychomycosis, which is applied to medical preparations containing active ingredients, ointment delivery, drug combination and other directions, can solve the problems of decreased curative effect, insignificant curative effect, insufficient permeability, etc., and achieves improvement of itching pain and remarkable therapeutic effect. , Improve the effect of clearing away heat and dampness

Active Publication Date: 2014-03-26
仲崇静
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many external medicines for the treatment of onychomycosis by western medicine and traditional Chinese medicine, but some western medicines have the disadvantages of strong irritation, easy to cause unbearable pain, easy skin allergies, and large side effects; some Chinese medicines have the disadvantages of insufficient permeability , the defect of long medication time
Some external medicines treat the symptoms but not the root cause, are volatile, have unbalanced drug effects, and act on the affected area for a long time, resulting in a significant decline in curative effect. The high price of external medicine increases the cost of treatment for patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] 105 parts of Sophora flavescens powder, 62 parts of white fresh skin powder, 62 parts of sheep's trotter root powder, 70 parts of Panax notoginseng powder, 81 parts of willow bark extract, 102 parts of benzoic acid, 112 parts of boric acid, 62 parts of glacial acetic acid, fennel pepper extract 275 parts, 30 parts of glycerin, 60 parts of vaseline, the preparation method of the fennel pepper extract: crush fennel and peppercorns through an 80-mesh sieve, take 100 parts of distilled water, add 1 part of fennel powder, 4 parts of pepper powder, mix Heat and boil for 40 minutes, cool to room temperature, soak for 24 hours, and filter through a 300-mesh sieve to prepare the fennel pepper extract. Described sophora flavescens powder, white fresh skin powder, Radix Radix Radix powder, Radix Notoginseng powder are all 300 mesh powders. The ointment is prepared by mixing and grinding Sophora flavescens powder, white fresh bark powder, Radix Radix Root powder, Panax notoginseng ...

Embodiment 2

[0016] 118 parts of Sophora flavescens powder, 78 parts of white fresh skin powder, 78 parts of sheep's trotter root powder, 89 parts of Panax notoginseng powder, 100 parts of willow bark extract, 118 parts of benzoic acid, 128 parts of boric acid, 80 parts of glacial acetic acid, fennel pepper extract 290 parts, 30 parts of glycerin, 60 parts of vaseline, the preparation method of the fennel pepper extract: crush fennel and peppercorns and sieve 100 meshes, take 100 parts of distilled water, add 2.5 parts of fennel powder, 5 parts of pepper powder, mix Heat and boil for 40 minutes, cool to room temperature, soak for 24 hours, and filter through a 300-mesh sieve to prepare the fennel pepper extract. Described sophora flavescens powder, white fresh skin powder, Radix Radix Radix powder, Radix Notoginseng powder are all 300 mesh powders. The ointment is prepared by mixing and grinding Sophora flavescens powder, white fresh bark powder, Radix Radix Root powder, Panax notoginseng ...

Embodiment 3

[0018] 110 parts of Sophora flavescens powder, 70 parts of white fresh skin powder, 75 parts of sheep's trotter root powder, 85 parts of Panax notoginseng powder, 95 parts of willow bark extract, 110 parts of benzoic acid, 120 parts of boric acid, 70 parts of glacial acetic acid, fennel pepper extract 280 parts, 30 parts of glycerin, 60 parts of vaseline, the preparation method of the fennel pepper extract: crush fennel and peppercorns through a 100-mesh sieve, take 100 parts of distilled water, add 2 parts of fennel powder, 4 parts of pepper powder, mix Heat and boil for 40 minutes, cool to room temperature, soak for 24 hours, and filter through a 300-mesh sieve to prepare the fennel pepper extract. Described sophora flavescens powder, white fresh skin powder, Radix Radix Radix powder, Radix Notoginseng powder are all 300 mesh powders. The ointment is prepared by mixing and grinding Sophora flavescens powder, white fresh bark powder, Radix Radix Root powder, Panax notoginseng...

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PUM

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Abstract

The invention relates to external ointment for treating onychomycosis, which is prepared from the following raw material medicines in parts by weight: 100 to 120 parts of radix sophorae flavescentis powder, 60 to 80 parts of cortex dictamni powder, 60 to 80 parts of rumex japonicus houtt. root powder, 70 to 90 parts of pseudo-ginseng powder, 80 to 100 parts of a willow bark extract, 100 to 120 parts of benzoic acid, 110 to 130 parts of boric acid, 60 to 80 parts of glacial acetic acid and 270 to 300 parts of an extracting solution of fennel and pepper. The external ointment has the advantages that the ointment combines Chinese and western medicines, sufficiently plays the characteristics of strong permeability and bactericidal activity of the western medicines, simultaneously improves pruritus, pain and skin allergy caused by strong irritation of the western medicines by the traditional Chinese medicines, takes the effects of diminishing inflammation and relieving pain, improves the effect of clearing away heat and drying dampness and achieves the effects of activating and harmonizing vital energy and blood, balancing yin-yang and smoothening the liver; the external ointment has short medication time, no pain, no side effects, and good curative effects, is low in cost and convenient to use and has an obvious treatment effect.

Description

technical field [0001] The invention relates to an external ointment for treating onychomycosis. Background technique [0002] Onychomycosis (onychomycosis) is a lesion caused by dermatophyte invading the nail plate, and is a fungal disease that occurs under the finger (toe) nail and under the nail. It is a skin disease in which fungal infection leads to changes in the structure and color of the nails, and is mutually contagious. The main manifestations of onychomycosis are: nail deformation, thickening, easy shedding, and separation. It has been found that onychomycosis is caused by more than 25 different fungal infections. Onychomycosis is a very difficult disease to cure. At present, there are many external medicines for the treatment of onychomycosis by western medicine and traditional Chinese medicine, but some western medicines have the disadvantages of strong irritation, easy to cause unbearable pain, easy skin allergies, and large side effects; some Chinese medicin...

Claims

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Application Information

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IPC IPC(8): A61K36/76A61K9/06A61P17/00A61P31/10A61K33/22A61K31/19
Inventor 仲崇静杨璐
Owner 仲崇静
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