Biological cellulose membrane manufacturing method

Abstract

The invention provides a biological cellulose membrane manufacturing method, comprising the steps of: preparing bacterial celluloses which is obtained through fermentation culturing of microbes capable of generating bacterial celluloses; placing the bacterial celluloses in an enclosed space containing water and having a temperature from 100 DEG to 140 DEG and a pressure from 1.2 kg / cm2 to 1.5 kg / cm2 for 25-75 minutes to obtain expanded bacterial celluloses; successively placing the expanded bacterial celluloses in an acid solution and water for cleaning to be neutral to obtain a biological cellulose membrane. The method can shorten manufacturing time; in addition, the expanded bacterial celluloses can increase the area of the bacterial celluloses to reduce cost.

Description

technical field [0001] The invention provides a method for producing a biological cellulose film, especially a method for producing a biological cellulose film that does not need to be cleaned with a large amount of alkali and / or acid solution and can shorten the manufacturing process. Background technique [0002] Bacterial cellulose (BC) is produced by the synthesis of microorganisms that can produce bacterial cellulose, and the bacterial cellulose raw material obtained by fermentation of microorganisms that can produce bacterial cellulose can be obtained after proper treatment. Biocellulose membranes with high hydrophilicity, high mechanical strength and extremely high biocompatibility (biocompatibility) make biocellulose membranes widely used in various fields, such as filtration membranes in the industrial field, dietary fiber in the food industry and Artificial skin, artificial blood vessels, etc. in the biomedical field. [0003] The prior art method for producing bi...

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Problems solved by technology

[0003] The prior art method for producing biological cellulose membranes, such as disclosed in U.S. Patent No. 8,053,216, is to ferment and culture microorganisms that can produce bacterial cellulose (BC) under appropriate conditions to obtain bacterial cellulose containing bacterial cellulose Raw materials, the bacterial cellulose raw material is rinsed with an alkaline solution, then neutralized and washed with an acidic solution, so that the pH value of the bacterial cellulose becomes neutral to form a biological cellulose film; the above-mentioned method for manufacturing a biological cellulose film It is necessary to use a large amount of alkaline and / or acidic solution to treat the bacterial cellulose separately, which is likely to generate secondary waste and cause unnecessary damage to the environment. In order to clean the bacterial cellulose to neutrality, the process time of this method is quite long

[0004] As disclosed in U.S. Patent No. 7,709,631, after removing bacterial cells with 2%-8% alkaline solution in the obtained fermentation culture mixture containing bacterial cellulose, the bacterial cells will turn yellow during the fermentation process. Brown, so 0.25% hydrogen peroxide (hydrogen peroxide) is used as a bleaching agent to bleach the bacterial cellulose to obtain a biological cellulose film; hydrogen peroxide easily releases oxygen free radicals in alkaline solution and can strengthen the bleaching effect effect, but the oxidized bacterial cellulose will reduce its tensile strength, which will lead to the embrittlement of the prepared biocellulose film

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