Method of extracting high-purity glabridin from licorice waste residue by adoption of new technology

Abstract

The invention provides a method of extracting high-purity glabridin from licorice waste residue by adoption of a new technology. The licorice waste residue is adopted as a raw material. A finished product of the glabridin is obtained by processes of extraction, impurity removal and adsorption. The method is advantageous in that: the high-purity glabridin is extracted from the licorice waste residue so that the waste resource is reutilized and the cost of the glabridin is largely reduced; a mixed solvent is used for extraction so that the extraction rate of the glabridin is maximized and the output is largely increased; room-temperature extraction is adopted, and therefore the production process is easy to operate, extracted impurities are less, the purity of the glabridin is high, solvent volatility is reduced, safety in production is improved and the cost is reduced; compared with purification processes adopting silica gel columns or a plurality of solvents for repeated extraction in the prior art, problems of low output and low production are solved and purification processes are largely simplified, thus facilitating industrial popularization and production; and the yield of the product is largely increased.

Description

technical field [0001] The invention relates to a method for extracting high-purity glabridin from licorice waste residue by adopting a new technology. Background technique [0002] Glabridin is a fat-soluble compound with molecular formula: C 20 h 20 o 4 , molecular weight: 324.36. It is mainly used in cosmetic whitening, and it is also used in the field of health food. It is mainly a diet food, which has been approved by the relevant departments of the European Union and the United States in 2011, and has begun to be used in healthy foods to prevent rebound in the weight loss process. [0003] At present, the patents for the production methods of such products currently in use in China include ZL200410079233.1 and ZL200510023860.8. [0004] The main method of patent ZL2004710079233.1 is to use a single solvent to heat and reflux to extract, filter, wash, concentrate, and dry under reduced pressure to obtain a crude product, which is then eluted with a variety of solve...

AI Technical Summary

Problems solved by technology

The biggest disadvantage of using the heating and reflux method for extraction: 1. After the licorice raw material is heated, many unnecessary impurities are extracted, which brings a lot of troubles to the next process, mainly because the separation of the upper silica gel column causes the process to be lengthened. , the lengthening of the process flow will lengthen the production cycle and reduce the production efficiency

The amount of solvent used increases, resulting in an increase in production costs

2. All flammable and volatile organic solvents are used in the extraction process of this patent. The organic solvents can be volatilized at room temperature, and the volatility is increased after heating, which brings many hidden dangers to the safety of the production process. , It also brings a lot of inconvenience to the operation in the production process

[0008] And the raw material adopted in the production method of patent ZL200410079233.1 and patent ZL200510023860.8 is licorice, the licorice residue after the production process like this is usually just thrown away, and this is a kind of very important composition glycyrrhizic acid resource in licorice. It is a big waste, and it is necessary to process and remove the glycyrrhizic acid component in the crude extraction species when producing licorice, and it is not conducive to cost control