Sputum cell treatment liquid and application thereof

Abstract

The invention discloses sputum cell treatment liquid and an application thereof. The sputum cell treatment liquid comprises a solution A and a solution B, wherein the solution A is mainly prepared from polyethylene glycol-400 and ethanol in a mixing manner; tendril-leaved fritillary bulb and peeled black bean particles are also soaked into the solution A; the solution B is prepared from the following components in parts by weight: 0.1-0.2 part of 1,4-dimercapto-2,3-butanediol, 17-20 parts of sodium chloride, 7-10 parts of disodium hydrogen phosphate, 0.5-1.5 parts of sodium dihydrogen phosphate, 0.5-1.5 parts of thymol crystals, 8-12 parts of glacial acetic acid and 1900-2,000 parts of distilled water; the solution A and the solution B are separately stored; the solution A is firstly utilized to process a sputum specimen, and then the solution B is utilized to process the sputum specimen when the sputum cell treatment liquid is used. The sputum cell treatment liquid disclosed by the invention is simple in sheet fabrication method, high in sheet fabrication quality, good in detection effect, and low in cost, and can be applied to large-scale production.

Description

technical field [0001] The invention relates to the technical field of medicaments, in particular to a sputum cell treatment solution and its application. Background technique [0002] Lung cancer is one of the common malignant tumors that endanger human life, and its morbidity and mortality rank first among malignant tumors in the world. At present, the diagnosis method of lung cancer mainly relies on imaging diagnosis such as X-ray and CT (computed tomography), so it can only be discovered after the cancer focus has developed to a certain size. Early detection of lung cancer is very important, and it is imperative to establish and popularize the method of early diagnosis. Sputum cytology is an important method for the early detection of lung cancer. This method has been available for more than 100 years, but there are many influencing factors. The reason is that in the traditional direct smear method, the cells are easy to autolyze and degenerate. Because the sputum cont...

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Problems solved by technology

Some people use paraffin embedding of sputum sediment to make slices, which is characterized by good tissue structure, but it takes a long time to make slices, and the interference of mucus, inflammatory cells and red blood cells cannot be eliminated

In order to avoid the shortcomings of the above-mentioned methods, a liquid-based cytology technology has been developed at home and abroad in recent years. It is an inspection method that is obviously superior to the traditional Pap smear. It has been widely used in gynecological vaginal and In the diagnosis and screening of cervical intraepithelial lesions and the diagnosis of lung cancer, the quality of the smears has been significantly improved, the cell structure of the thin slices is clearly displayed, the background of the smears is clean, the contrast is strong, and the detection rate of cancer cells is significantly improved. The liquid base used in the method is mostly imported, the price is relatively expensive, the production process is cumbersome, and the sputum dissolving agent sometimes easily denatures the cells, so it is difficult to popularize and apply it in many grassroots hospitals

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