Compound preparation for treating pancytopenia and preparation method thereof

Abstract

The invention provides a compound preparation for treating pancytopenia, which is small in toxic and side effect and obvious in treatment effect. The compound preparation is mainly prepared from the following raw medical materials by weight percent: 15% to 18% of bovine bone marrow, 8% to 10% of placenta hominis, 8% to 10% of rehmannia glutinosa, 8% to 10% of Chinese yam, 8% to 10% of lycium barbarum, 8% to 10% of dogwood, 15% to 18% of medicinal cyathula root, 8% to 10% of deerhorn glue, 8% to 10% of semen cuscutae and 8% to 10% of tortoise plastron glue. According to the compound preparation, the functions of an ancient formula 'Zuogui Pill' capable of enriching yin and nourishing kidney as well as replenishing essence and benefiting marrow are utilized; and yang-tonifying medicines are added into the yin-tonifying formula, so that the compound preparation has the functions of enriching yin and nourishing the kidney, replenishing essence and benefiting marrow as well as reinforcing qi and nourishing blood under the formula synergy in manners of reinforcing yang from yin and reinforcing yin from yang.

Description

technical field [0001] The invention belongs to the field of medicine, and is a compound preparation for treating pancytopenia and kidney yin deficiency, mainly suitable for aplastic anemia, acute leukemia, myelodysplastic syndrome, megaloblastic Pancytopenia caused by anemia, immune hemolytic anemia, paroxysmal hemoglobinuria, hypersplenism, primary myelofibrosis, etc. Background technique [0002] Pancytopenia (PCP) is one of the common diseases in the blood system, mainly refers to peripheral blood red blood cell (RBC) or hemoglobin (Hb), white blood cell (WBC), platelet (PLT) counts continue to be lower than the normal range. Clinically, the main manifestations are anemia, hemorrhage, and infection. It can be caused by a variety of etiologies. Pancytopenia is mainly caused by hematopoietic system diseases, and a small part can be caused by non-hematopoietic system diseases. Aplastic anemia, acute leukemia, myelodysplastic syndrome, megaloblastic anemia, immune hemolyti...

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Problems solved by technology

[0003] At present, the general whitening medicine such as vitamin B4 is commonly used in Western medicine clinically, and the curative effect is uncertain; biological factor preparations such as recombinant human granulocyte colony stimulating factor are expensive and dose-dependent; immunosuppressants such as glucocorticoids are only suitable for self Patients with agranulocytosis caused by immune granulocytopenia and immune mechanism have serious side effects. Lithium carbonate can stimulate bone marrow to produce granulocytes, but its therapeutic dose is close to the dose that produces toxic and side effects, so it is rarely used clinically.

[0004] At present, most studies on pancytopenia focus on symptomatic and supportive treatment, and few can treat symptoms and signs from the perspective of traditional Chinese medicine.

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