Method of quickly preparing calcium phosphate coating containing third-party beneficial ions

Abstract

The invention provides a method of preparing a calcium phosphate coating containing third-party beneficial ions in a microwave-assisted manner within a short time. The method comprises the following steps: microwave heating a reaction solution containing phosphate anions and calcium ions to form the calcium phosphate coating; and adding the third-party beneficial ions into the reaction solution to prepare the calcium phosphate coating containing the third-party beneficial ions. The method provided by the invention has the advantages of efficiency, low energy consumption, low investment and easiness in control and can fully coat orthopaedical or dental implantation apparatuses and stents with complex structures and the like. The obtained calcium phosphate coating containing the third-party beneficial ions can be applied to the biomedical engineering field of hard tissue repair.

Description

technical field

[0001] The invention relates to the technical field of medical biomaterials, in particular to a method for rapidly preparing a calcium phosphate coating containing third-party beneficial ions. technical background

[0002] Calcium phosphate has a similar chemical composition and crystal structure to the main minerals in human bones and teeth. It is the main inorganic component of human bone tissue and is a typical bioactive material. However, the mechanical properties of calcium phosphate ceramics are poor, and its bending strength and fracture toughness are lower than those of human compact bone, making it difficult to use in the bearing parts of the human body. Depositing calcium phosphate ceramic coatings on substrates composed of ceramics, metals, polymers, and composite materials can overcome the brittleness of calcium phosphate ceramics and improve the bearing capacity of implants. At the same time, the good biological activity of calcium phosphate cer...