A kind of polypeptide, polypeptide derivative, pharmaceutically acceptable salt of polypeptide and pharmaceutical composition

The technology of a composition and a medicinal salt, which is applied in the field of medicine and pharmacy, can solve the problems of short plasma half-life, and achieve the effects of long plasma half-life, improving islet function and good stability.
CN104045703BActive Publication Date: 2021-04-06SHENZHEN HIGHTIDE BIOPHARM
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN HIGHTIDE BIOPHARM
Publication Date
2021-04-06

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Abstract

In order to overcome the problems of short plasma half-life and low activity of the insulin-promoting polypeptide in the prior art, the present invention provides a polypeptide. At the same time, the invention also discloses derivatives, pharmaceutically acceptable salts and pharmaceutical compositions of the above polypeptides. The polypeptide provided by the invention has high stability in blood and long half-life.
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Description

[0001] This application is based on, and claims priority from, an earlier PCT international application (application number PCT / CN2013 / 072771) filed on March 15, 2013, the entire content of which is hereby incorporated by reference into this application. technical field

[0002] The present invention mainly relates to the fields of medicine and pharmacy, especially a polypeptide, derivatives of the polypeptide, pharmaceutically acceptable salts and pharmaceutical compositions. Background technique

[0003] More than 300 million people worldwide suffer from and suffer from diabetes mellitus (DM). There are two main types of diabetes: type 1 diabetes (T1D) and type 2 diabetes (T2D). Type 1 diabetes is caused by the body's inability to produce insulin and the patient needs to be treated with daily insulin. Type 2 diabetes is caused by insulin resistance, which means that the body's cells cannot use insulin properly. At present, there are many proven and effective non-insulin t...

Claims

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