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New application of murraya tetramera huang and extract thereof in preparation of medicines

A technique for counting the incense sticks and extracts, which is applied to the field of new uses of natural botanical medicinal materials and/or their extracts in medicines for the treatment of heart disease, and can solve the problem that the medicines for heart disease are not reported in literature, etc.

Active Publication Date: 2014-11-05
YUNNAN SUNSAIL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Past dynasties and various ethnic minorities have used Jiulixiang to treat colds, fevers, coughs, stomach pains, rheumatic paralysis, bruises, bruises, itchy skin, and eczema. There are also many related patents and documents. However, there is no literature report on using Sishu Jiulixiang as a drug for treating heart disease.

Method used

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  • New application of murraya tetramera huang and extract thereof in preparation of medicines
  • New application of murraya tetramera huang and extract thereof in preparation of medicines
  • New application of murraya tetramera huang and extract thereof in preparation of medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0137] Example 1: Shuangshujiulixiang Capsules

[0138] Recipe: 1000 copies of Jiulixiang.

[0139] Preparation method: Take 800 parts of Sishu Jiulixiang leaves, extract twice with acetone at room temperature, the first time is 48 hours, and the second time is 40 hours, combine the infusion, recover acetone, and concentrate the extract into a thick paste for later use. Take 200 parts of Sishujiuli xianggen, extract twice with drinking water according to the decoction method, each time for 1 hour, combine the decoction, concentrate into a thick paste, mix with the aforementioned thick paste, dry at 55°C-65°C, and pulverize into fine powder, and prepare capsules according to the conventional process.

Embodiment 2

[0140] Example 2: Shuangshujiulixiang Capsules

[0141] Recipe: 1000 copies of Jiulixiang.

[0142] Preparation method: Take 900 parts of Sishu Jiulixiang leaves, extract twice with acetone at room temperature, the first time is 48 hours, and the second time is 40 hours, combine the infusion, recover acetone, concentrate the extract into a thick paste, and extract it at 55 ℃ ~ 65 ℃ dry, crushed into fine powder for later use. Another 100 parts of Sishu Jiulixianghua were taken, directly crushed into fine powder, mixed with the fine powder of the above-mentioned extract, and prepared into capsules according to the conventional process.

Embodiment 3

[0143] Example 3: Sishujiulixiang Tablets

[0144] Recipe: 1000 copies of Jiulixiang.

[0145] Preparation method: Take 1,000 parts of the whole plant of Sishu Jiulixiang, crush it into a coarse powder, extract it twice with drinking water according to the decoction method, each time for 1 hour, combine the decoction, concentrate it into a thick paste, and dry it at 55℃~65℃ , crushed into fine powder, and prepared tablets according to the conventional process.

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, in particular relates to new application of a natural plant medicine material and / or extract thereof in medicines for treatment of heart disease, and relates to application of murraya tetramera huang and / or extract thereof in the medicines for treatment of heart disease. The murraya tetramera huang is obtained by crushing any one of leaf, branch, root, flower and fruit of murraya tetramera huang or combination thereof to use as a medicine; the extract is obtained by crushing the murraya tetramera huang, leaching at room temperature, heating for reflux and supercritically extracting, and a solvent used for extraction is a liquid prepared by mutually mixing water and ethanol in any proportion for dissolving, or a liquid prepared by mutually mixing acetone, ether, petroleum ether, chloroform and ethyl acetate in any proportion for dissolving, or liquid CO2. The murraya tetramera huang and / or extract thereof are / is mainly used for comprehensive treatment of coronary heart disease, rheumatic heart disease, hypertensive heart disease, pulmonary heart disease, myocardiopathy, cardiac tumor and vasculopathy. Animal experiments and clinical experiments show that the prepared medicinal preparation has no obvious adverse reactions and toxic and side effects, and is a natural plant medicine capable of providing safe and efficient treatment of heart disease for patients.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a new application of natural plant medicines and / or extracts thereof in medicines for treating heart diseases. technical background [0002] Today, people generally pay attention to the "killing without negotiation" cancer; but they don't know that arteriosclerosis is the "first terminator" of human life. According to WHO statistics, cardiovascular disease is the number one killer in the world, with approximately 17.5 million deaths due to heart disease and stroke each year. At present, heart disease is mostly treated with surgery and western medicine. However, because western medicine needs to be taken for a long time to treat heart disease, it will cause great damage to the patient's liver, kidney, intestine, stomach and other organs. Therefore, doctors, experts and patients at home and abroad are looking for Green medicine with low toxicity a...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61P9/10A61P9/00A61P35/00
Inventor 温先敏
Owner YUNNAN SUNSAIL PHARMA
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