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Method for producing calamine pastes

A production method and gypsum technology, applied in ointment delivery, pharmaceutical formula, aerosol delivery, etc., can solve the problems of uniform dispersion, difficulty in calamine powder and zinc oxide powder, etc., and achieve the effect of improved uniformity and beautiful appearance

Active Publication Date: 2014-12-03
HUNAN ER KANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The object of the present invention is to provide a kind of production method of calamine plaster, solve the defective that existing calamine plaster production method exists, namely the problem that calamine powder and zinc oxide powder are difficult to disperse evenly in plaster matrix

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Calamine plaster is prescribed by weight as:

[0046] Calamine very fine powder 50g,

[0047] Zinc oxide ultrafine powder 50g,

[0048]Ethylparaben 0.01g,

[0049] Glyceryl monostearate 45g;

[0050] Mixed fatty acid glycerides 40g;

[0051] Sodium Lauryl Sulfate 30g

[0052] 50g peanut oil;

[0053] Polyethylene glycol 200 400g;

[0054] Polyethylene glycol 1000 200g;

[0055] Polyethylene glycol 2000 100g;

[0056] Add water to 1000g.

[0057] The operation steps are:

[0058] 1) Spread 50g of calamine superfine powder and 50g of zinc oxide superfine powder in a flat container to a thickness of about 0.5-1cm, sterilize at 150°C for 4 hours, and set aside;

[0059] Take each component of the ointment matrix and sterilize at 150°C for 4 hours for later use;

[0060] 2) Put 45g mono-distearic acid glycerides and 200g mixed fatty acid glycerides into a container, heat to melt, add 50g peanut oil while keeping stirring at 85°C, keep stirring to obtain an oil pha...

Embodiment 2

[0064] Calamine plaster is prescribed by weight as:

[0065] Calamine very fine powder 150g;

[0066] Zinc oxide ultrafine powder 50g;

[0067] Resorcinol 5g;

[0068] Glyceryl monostearate 40g;

[0069] Mixed fatty acid glycerides 30g;

[0070] Sodium lauryl sulfate 55g;

[0071] 30g peanut oil;

[0072] Polyethylene glycol 600 340g;

[0073] Polyethylene glycol 4000 460g;

[0074] Add water to 1000g.

[0075] Except that the prescription is different, the preparation method is the same as in Example 1.

Embodiment 3

[0077] Calamine plaster is prescribed by weight as:

[0078] Calamine very fine powder 100g;

[0079] Zinc oxide ultrafine powder 100g;

[0080] Thymol 0.5g;

[0081] Resorcinol 1.5g;

[0082] Glyceryl monostearate 60g;

[0083] Mixed fatty acid glycerides 80g;

[0084] Sodium lauryl sulfate 60g;

[0085] 25g peanut oil;

[0086] Macrogol 200 300g

[0087] Polyethylene glycol 1000 100g;

[0088] Polyethylene glycol 2000 50g;

[0089] Add water to 1000g.

[0090] Except that the prescription is different, the preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses a method for producing calamine pastes. The method for producing calamine pastes comprises the steps of (1) sterilizing calamine fine powder, zinc oxide fine powder and paste matrix; (2) mixing; (3) mixing with a bacteriostatic agent; and (4) filling to obtain finished products. The calamine pastes produced according to the method have the advantage of good homogeneity, and calamine pastes of different performances are obtained by adjusting the components and proportions of polyethylene glycol in the paste matrix.

Description

technical field [0001] The invention relates to a production method of calamine plaster, specifically a production method of calamine ointment, especially a production method of calamine ointment containing thymol or resorcinol, which belongs to medicine manufacturing field. Background technique [0002] Calamine is a carbonate mineral calcite group smithsonite, mainly containing zinc carbonate. After excavation, wash, dry and remove miscellaneous stones. The properties of this product are block aggregates, irregular blocks, off-white or light red. The surface is powdery, dull, uneven, porous, and honeycomb-like. Lightweight and fragile. Odorless, slightly astringent taste. Functions and indications: detoxification, improving eyesight and removing nebula, reducing dampness, relieving itching and suppressing sores. It is used for conjunctival congestion, swelling and pain, red and rotten eyes, pannus pterygium, unrestrained ulcer, dripping pus, eczema, and itchy skin. ...

Claims

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Application Information

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IPC IPC(8): A61K33/30A61K9/06A61K47/34A61K47/44A61K47/14A61K47/20A61K47/10A61P27/02A61P17/00A61P17/02
Inventor 帅放文王向峰章家伟
Owner HUNAN ER KANG PHARMA