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A kind of musk hemorrhoid suppository and its preparation method

A technology for musk hemorrhoids and raw materials, which is applied in the directions of suppository delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., can solve the problems of easy precipitation of borneol, and achieve the effects of stable and reliable quality, sufficient supply and easy operation.

Active Publication Date: 2017-12-22
MAYINGLONG PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the deficiencies in the prior art, the object of the present invention is to provide a musk hemorrhoid suppository, which has a reasonable formula, is convenient to use, effectively improves the stability of borneol in the suppository, and obviously improves the stability of the product in a continuous low temperature environment. The problem of easy precipitation of borneol; improve the stability of the appearance of the product at low temperature

Method used

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  • A kind of musk hemorrhoid suppository and its preparation method
  • A kind of musk hemorrhoid suppository and its preparation method
  • A kind of musk hemorrhoid suppository and its preparation method

Examples

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Embodiment 1

[0041] A kind of musk hemorrhoid suppository, the suppository that it is made of the raw material of following weight ratio:

[0042]

[0043] A preparation method of musk hemorrhoid suppository, the steps are:

[0044] A. Grind pearls, panax notoginseng and gallnut through 80 or 100 mesh sieves respectively;

[0045] B. Mix belladonna liquid extract and calamine in a ratio of 1:1 (belladonna liquid extract 35: calamine 35), dry at 80 or 85 or 90 or 95 or 100°C, and dry over 80 or 100 mesh screens obtain a mixture of belladonna liquid extract and calamine;

[0046] C, the mixture obtained in step B is mixed evenly with pearl powder, Panax notoginseng powder, gallnut powder, bezoar, artificial musk, calamine (the first remaining amount that has not been added is 115), and a kind of mixed medicinal powder is obtained;

[0047] D. The mixed medicinal powder is pulverized by micronization (5um or 6 or 7 or 8 or 9 or 10um) to obtain the original powder.

[0048] E. Heat the d...

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Abstract

The invention discloses a musk hemorrhoid suppository and a preparation method thereof. The suppository is composed of bezoar, pearl, musk, panax notoginseng, gallnut, borneol, belladonna liquid extract, calamine, lanolin, dimethyl maple, mixed fatty acid glycerin made from esters. Steps: A, crushing pearls, notoginseng, gallnut; B, mixing belladonna fluid extract with calamine, drying; C, mixing the mixture with pearl powder, notoginseng powder, gallnut powder, bezoar, artificial musk, Mix calamine; D. Grind the medicinal powder to obtain the original powder; E. Heat dimethyl maple, add borneol to dimethyl maple and stir to dissolve; F. Heat lanolin and cool down; G. Mix fatty acid glycerin Heating the ester, adding lanolin solution, raw powder, borneol, and dimethyl methazine to mix, cooling down to make thrombus. The formula is reasonable, easy to use, effectively improves the stability of borneol in the plug, and obviously improves the problem that borneol is easy to precipitate in the continuous low temperature environment of the product; improves the stability of the appearance of the product at low temperature.

Description

technical field [0001] The invention relates to a musk hemorrhoid suppository, specifically, the drug combination is mainly used for treating various hemorrhoids, and also relates to a preparation method of the musk hemorrhoid suppository. Background technique [0002] At present, there are many drugs used to treat anorectal diseases. The chemically synthesized drugs are unsatisfactory due to their clinical efficacy and side effects. Traditional Chinese medicine preparations have received unanimous praise from experts and patients due to their remarkable curative effect and low toxicity. The suppositories used to treat anorectal diseases on the market generally contain a large amount of borneol, such as the musk hemorrhoid suppository produced by Mayinglong Pharmaceutical Co. Seven borneol suppositories, etc., are affected by the solubility of the preparation. When the ambient temperature is continuously low (less than 10°C), a large amount of borneol is easily precipitated ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/02A61K36/81A61K47/44A61K47/20A61P9/14A61K31/045A61K33/30A61K35/32A61K35/413A61K35/618A61K35/64
Inventor 陈平夏军喻红周秋松
Owner MAYINGLONG PHARMA GROUP