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Application of melancholy-dispelling liver-soothing capsule in preparation of antiulcer medicines

A Jieyuganshu capsule and anti-ulcer technology, which is applied in the field of medicine and can solve the problems that the application of anti-ulcer therapy has not yet been discovered.

Inactive Publication Date: 2015-01-07
三普药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its application in anti-ulcer therapy has not yet been discovered

Method used

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  • Application of melancholy-dispelling liver-soothing capsule in preparation of antiulcer medicines
  • Application of melancholy-dispelling liver-soothing capsule in preparation of antiulcer medicines
  • Application of melancholy-dispelling liver-soothing capsule in preparation of antiulcer medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Anti-ulcer Animal Experiment of Jieyuganshu Capsule

[0012] 1 material

[0013] 1.1 Drugs and reagents

[0014] Jieyu Ganshu extract (extracted by our own laboratory), consists of Sichuan Swertia, Ganqing Qinglan, Astragalus, Codonopsis, Rabbit Ear Grass, Schisandra, Radix Paeoniae Alba, Angelica, Ophiopogon japonicus, Bupleurum, Scutellaria, Curcuma, Composition of medicines such as Citrus aurantii Fructus, Poria cocos and Licorice. During the experiment, the required concentration was prepared with double distilled water.

[0015] Absolute ethanol, specification: 500ml, AR, batch number: 20100827, Sinopharm Chemical Reagent Co., Ltd. Formaldehyde, specification: 500ml, AR, batch number: 10092911035, Nanjing Chemical Reagent Co., Ltd.

[0016] Ranitidine hydrochloride capsules, specification: 0.15g, batch number: 121119, Jiangsu Huanghe Pharmaceutical Co., Ltd. NO content determination kit, Nanjing Jiancheng Institute of Bioengineering, batch number: 20130926.

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Abstract

An application of a melancholy-dispelling liver-soothing capsule in preparation of antiulcer medicines is disclosed. Animal experiments and research show that: the melancholy-dispelling liver-soothing capsule has certain protection functions for an absolute-ethanol-induced acute gastric ulcer model, a water-immersion-induced stress ulcer model and a chronic acetic acid ulcer model.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Jieyu Ganshu capsules in the preparation of anti-ulcer medicines. Background technique [0002] Peptic ulcer refers to the ulcer that occurs when the gastrointestinal mucosa is digested by gastric acid and pepsin. It is a common disease that occurs mainly in the stomach and duodenum. Frequently-occurring disease belongs to the category of epigastric pain in traditional Chinese medicine, and its clinical manifestations are chronic, periodic, and rhythmic epigastric pain. The disease is a chronic disease, difficult to cure, easy to relapse, severe cases may also have complications such as upper gastrointestinal bleeding, perforation, pyloric obstruction, etc., seriously endangering human health. [0003] The treatment of peptic ulcer in modern medicine is mainly to eliminate the cause of disease, relieve symptoms, promote ulcer healing, and prevent recurrence...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/48A61P1/04
CPCA61K36/51A61K9/48A61K36/076A61K36/232A61K36/233A61K36/344A61K36/481A61K36/484A61K36/53A61K36/539A61K36/57A61K36/65A61K36/71A61K36/752A61K36/79A61K36/8968A61K36/898A61K36/9066
Inventor 史公权邹存生马俊仓吴留强夏彬牛蓉贺生玲李成秀
Owner 三普药业有限公司
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