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Compositions containing extracts of malva neglecta

A technology of mallow round leaf and composition, which is applied in the field of compositions containing plant extracts, and can solve the problems of topical use, limiting wounds and tumors, etc.

Inactive Publication Date: 2015-02-04
JOHNSON & JOHNSON CONSUMER COPANIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The topical use of mallow mallow reported in the prior art (S. Foster and JA Duke, Medicinal Plants and Herbs, pp. 170-171, New York, Houghton Mifflin Company 2000) is limited to wounds and tumors

Method used

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  • Compositions containing extracts of malva neglecta
  • Compositions containing extracts of malva neglecta
  • Compositions containing extracts of malva neglecta

Examples

Experimental program
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Effect test

preparation example Construction

[0030] Any suitable method of preparing the mallow mallow extract for use in accordance with the invention may be used. Suitable extracts can be obtained using conventional methods including, but not limited to, direct extraction from biomass by grinding, maceration, extrusion, pressing, pounding, centrifugation, and / or methods such as cold percolation, Stirring / distillation, microwave-assisted extraction, sonication, supercritical / subcritical CO with or without polar modifiers 2 Compressed gas extraction, pressurized solvent extraction, accelerated solvent extraction, surfactant assisted pressurized hot water extraction, oil extraction, membrane extraction, Soxhlet extraction, golden finger distillation / extraction and / or such as in the award to Integrated Botanical Technologies, US Patent Nos. 7,442,391, 7,473,435, and 7,537,791 to LLC, among others, or by other methods such as solvent extraction and the like. In particular, the extract according to the invention is preferab...

example 1

[0137] Example 1: Preparation of Mallow Musculus Extract (E1) from Aerial Parts

[0138] Roundleaf mallow plants were field collected in New York. Species identification is based on macroscopic morphological characteristics [Gleason & Cronquist, Manual of Vascular Plants; D Van Nostrand Company, New York: pp. 462-463]. Plants were cleared of soil and debris and separated into aerial parts and roots. Approximately 80 g of fresh aerial plant material was homogenized in a blender with 200 mL of 80% aqueous methanol; the suspension was maintained in constant motion for a total of 24 hours. The resulting suspension was then filtered and dried at low pressure using a rotary evaporator not exceeding 40°C. After filtration, the remaining raw material is extracted again as described above. The combined dry matter from both extractions was designated as the crude extract, approximately 2.1 g, for a total yield of 6.6%. The crude extract was resuspended in 100 mL of water, and a li...

example 2

[0139] Example 2: Preparation of mallow extracts from aerial parts (E2 and E3)

[0140] Mallow musculus plants were harvested and extracted as described in Example 1 to obtain a crude extract. The crude extract was resuspended in 100 mL of water and a liquid-liquid solvent partition was performed in a separatory funnel using three equal parts of hexane followed by three equal parts of ethyl acetate.

[0141] The three ethyl acetate partitions were combined and dried under low pressure using a rotary evaporator not exceeding 40 °C to obtain a total mass (E2) of approximately 73 mg in 0.2% yield. The remaining aqueous phase was dried under low pressure using a rotary evaporator not exceeding 40° C. to obtain a total mass (E3) of approximately 1.8 g, with a total yield of 5.6%.

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PUM

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Abstract

The present invention relates to a skin care composition comprising an extract of Malva neglecta and a cosmetically acceptable topical carrier. Non-polar and / or lipophilic extracts have been found to be particularly effective in improving skin barrier function, improving the appearance of at least one sign of aging in skin, and / or lightening skin. The composition may further comprise an agent, such as an active cosmetic agent, for further treating the skin condition.

Description

technical field [0001] The present invention relates to compositions comprising plant extracts for use on the skin. More specifically, the present invention relates to compounds comprising mallow (Malva rotifera) for improving the condition and appearance of the skin, such as by enhancing the skin barrier protection, improving, reducing, inhibiting or delaying the appearance of at least one sign of skin aging and / or brightening the skin. neglecta) extract composition. Background technique [0002] Roundleaf mallow is often named "weed." Native to the "Old World", it has naturalized throughout North America. Mallow is native to almost all of Europe, from Northern Europe (e.g. Denmark, Ireland, Norway, Sweden, United Kingdom), Central Europe (e.g. Austria, Belgium), Southeastern Europe (e.g. Albania, Bulgaria, Croatia, etc.) to Southwestern Europe (e.g. France, Portugal, Spain). It is also found in West Asia, the Arabian Peninsula, Northwest Asia (eg, Armenia, Georgia, Kaz...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/10A61Q19/00A61Q5/02A61Q5/12A61Q9/02A61Q19/08A61Q17/04
CPCA61K8/97A61Q17/00A61Q19/08A61Q19/00A61Q19/02A61K8/9789A61P17/00A61P17/16
Inventor M·D·索斯霍K·马哈茂德A·帕帕斯Y·胡K·雷纳森S·冲R·帕萨M·兰德哈瓦
Owner JOHNSON & JOHNSON CONSUMER COPANIES
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