Side-chain-type difluoro monomer and synthesis method thereof
A synthesis method and technology of fluorine monomers, applied in the field of materials, can solve the problems of difficult synthesis, few types of side chain monomers, and high solubility
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Embodiment 1
[0031] Taking the side chain difluoromonomer with the following structural formula as an example, the specific preparation method is as follows:
[0032]
[0033] 1. Preparation of compound a
[0034] Under the protection of nitrogen, add 0.79g (32.42mmol) of magnesium powder and 5mL of dry tetrahydrofuran to a 100mL three-necked flask, turn on magnetic stirring, increase the temperature to 65℃, and slowly add 5.00g (27.02mmol) of 3,5-dimethyl A mixed solution of bromobenzene and 40mL dry tetrahydrofuran was stirred at 65°C for 3 hours to prepare a Grignard reagent, and then slowly dropwise added 3.76g (27.02mmol) 2,6-difluorobenzonitrile and 40mL dry tetrahydrofuran mixed solution, Continue to stir at 65°C for 6 hours. After the reaction is complete, add 80 mL of 0.1mol / L hydrochloric acid aqueous solution, stir and reflux for 12 hours at 80°C, wash the reaction solution to neutrality, concentrate the organic phase to prepare compound a, The yield is 65.2%, and the structural cha...
Embodiment 2
[0042] Taking the side chain difluoromonomer with the following structural formula as an example, the specific preparation method is as follows:
[0043]
[0044] In step 3 of Example 1, the 3,5-dimethylphenylboronic acid used was replaced with equimolar 2,4-dimethylphenylboronic acid, and the other steps were the same as in Example 1, to prepare side chain difluoro The yield of the monomer is 66.1%, and the structure characterization data are as follows:
[0045] 1 H-NMR(DMSO-d 6 Is the solvent, TMS is the internal standard, 300MHz, ppm): 7.66 (m, 1H), 7.49 (s, 1H), 7.40 (d, 2H), 7.26 (t, 2H), 6.99 (s, 1H), 6.98 ( s, 1H), 6.92 (s, 1H), 3.87 (s, 2H), 2.29 (s, 3H), 2.19 (s, 6H).
Embodiment 3
[0047] Taking the side chain difluoromonomer with the following structural formula as an example, the specific preparation method is as follows:
[0048]
[0049] In step 3 of Example 1, the 3,5-dimethylphenylboronic acid used was replaced with equimolar 4-methylphenylboronic acid, and the other steps were the same as in Example 1, to prepare a side chain difluoromonomer, The yield is 67.2%, and the structural characterization data are as follows:
[0050] 1 H-NMR (DMSO-d6 is solvent, TMS is internal standard, 300MHz, ppm): 7.67 (m, 1H), 7.46 (s, 1H), 7.30 (d, 2H), 7.22 (t, 2H), 6.98 ( s, 4H), 3.88 (s, 2H), 2.29 (s, 3H), 2.19 (s, 3H).
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