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Maca superfine powder as well as preparation method and application thereof

A technology of ultra-fine powder and ultra-fine powder, which is applied in the direction of making medicines into special physical or taking forms, powder delivery, pharmaceutical formulations, etc., and can solve the problems of limited application of maca

Active Publication Date: 2015-02-18
SHANGHAI JINCHENG PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] But at present, the application of maca in medicine is still relatively limited. How to process maca with ultra-fine powder technology, so that it can have better curative effect in the treatment of some diseases

Method used

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  • Maca superfine powder as well as preparation method and application thereof
  • Maca superfine powder as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The steps of making maca superfine powder decoction pieces are as follows:

[0034] Step 1: Impurity removal and cleaning system, select maca raw materials, remove impurities, and require the impurity content not to exceed 1% after purification;

[0035] Step 2: freeze-drying, and then sterilizing after drying;

[0036] Step 3: Grinding the dried maca to a particle size of 0.5 micron, and then ultrafinely pulverizing in a jet mill to obtain a micropowder. The conditions for said ultrafine pulverization are: the pulverization temperature is 18° C. The pressure is 1.5Mpa, the crushing pressure is 3Mpa, the air velocity is 190m / s, and the crushing time is 1h;

[0037] Step 4: Mix maca superfine powder and auxiliary material starch evenly in the container, granulate and press into tablets.

Embodiment 2

[0042] The steps of making maca superfine powder decoction pieces are as follows:

[0043] Step 1: Impurity removal and cleaning system, select maca raw materials, remove impurities, and require the impurity content not to exceed 1% after purification;

[0044] Step 2: freeze-drying, and then sterilizing after drying;

[0045] Step 3: Grinding the dried maca to a particle size of 2 microns, and then ultrafinely pulverizing in a jet mill to obtain a micropowder. The conditions for said ultrafine pulverization are: the pulverization temperature is 25° C. The pressure is 3Mpa, the crushing pressure is 7Mpa, the air velocity is 300m / s, and the crushing time is 3h;

[0046] Step 4: Mix maca superfine powder and auxiliary material β-cyclodextrin evenly in the container, granulate and press into tablets.

Embodiment 3

[0051] The steps of making maca superfine powder decoction pieces are as follows:

[0052] Step 1: Impurity removal and cleaning system, select maca raw materials, remove impurities, and require the impurity content not to exceed 1% after purification;

[0053] Step 2: freeze-drying, and then sterilizing after drying;

[0054] Step 3: Grinding the dried maca to a particle size of 3 microns, and then superfinely pulverizing in a jet mill to obtain a micropowder. The conditions for the superfine pulverization are: the pulverization temperature is 20° C. The pressure is 2Mpa, the crushing pressure is 5Mpa, the air velocity is 250m / s, and the crushing time is 2h;

[0055] Step 4: Mix the superfine maca powder and auxiliary material dextrin in the container evenly, granulate and press into tablets.

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Abstract

The invention discloses maca superfine powder as well as a preparation method and application thereof. The grain size of the maca superfine powder is measured by a dry method laser granulometry meter and is 0.5-3 micrometers. The preparation method of the powder comprises the following steps: 1 removing impurities and cleansing; 2 freeze-drying, and carrying out sterilization treatment after drying; 3 grinding dry maca powder into coarse powder, then carrying out superfine-grinding in a jet mill, and thus obtaining the superfine powder with the grain size being 0.5-3 micrometers. The conditions of superfine-grinding are as follows: the grinding temperature is 18-25 DEG C, the pressure of a superfine-grinding machine when the powder enters the superfine-grinding machine is 1.5-3Mpa, the grinding pressure is 3-7Mpa, the airflow velocity is 190-300m / s, and the grinding time is 1-3h. The maca superfine powder is used for treating low immunity, physical fatigue and sexual dysfunction and has the advantages of being significant in curative effect and stable in condition of patients, improving the survival quality of patients, increasing the weight of patients, improving the immunologic function of patients, and being safe in medication.

Description

technical field [0001] The invention relates to a powder medicine, in particular to a maca superfine powder and a preparation method and application thereof. Background technique [0002] Maca (Maca), also known as Peruvian ginseng, maka, ayak chichira, ayak willku, etc., is native to the South American Andes at an altitude of 3500-4500 meters and is mainly distributed in the Puno ecological zone in central Peru and the southeastern city of Puno in Peru. A plant of the genus Lepidium in the flower family (Cruciferae). [0003] Maca is a plateau plant of the cruciferous family, native to the plateau plant above 4,000 meters in the Peruvian Andes in South America. The unique macamide and macaene have a significant effect on balancing the secretion of human hormones. Maca has the effects of anti-fatigue, increasing sperm quality, replenishing physical strength, improving impotence and premature ejaculation, improving sleep, anti-menopausal, active fertility, and enhancing mem...

Claims

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Application Information

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IPC IPC(8): A61K36/31A61K9/14A61P37/04A61P39/00A61P15/00A61J3/02
CPCA61J3/02A61K9/14A61K9/2018A61K9/205A61K9/2059A61K36/31A61K2236/13A61K2236/15A61K2236/17
Inventor 傅苗青左克强
Owner SHANGHAI JINCHENG PHARMACEUTICAL CO LTD
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