Formula of blueberry anthocyanin tablets and production process of blueberry anthocyanin tablets
A raspberry anthocyanin tablet and a production process technology are applied in the field of formulation and production process of blueberry anthocyanin tablets, and can solve the problems of general blueberry anthocyanin purity, inability to meet market demands, large loss of nutrients, and the like, so as to maintain normal The effect of permeability, inhibition of platelet aggregation, rapid absorption and utilization
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Embodiment 1
[0022] The process is divided into nine steps. Firstly, (1) Raw material picking: pick the best wild blueberries, and transport them to the pharmaceutical factory under low-temperature refrigeration throughout the whole process, and the transportation time should not exceed 48 hours; (2) Grinding: Ultrasonic continuous countercurrent extraction of wild blueberries High-purity anthocyanins are put into a grinder for pulverization; then (3) sieving powder: sieve the blueberry powder to remove large particles of impurities; then (4) making soft materials: after sieving Add ethanol with a concentration of 50% to the blueberry powder, and stir evenly; then perform (5) low-temperature granulation: put the prepared soft material into a granulator, perform low-temperature granulation treatment, and keep the temperature at 68°C throughout the process Carry out (6) wet granulation again: the magnesium stearate that will account for the mass fraction of total mass is 2% and the crystallin...
Embodiment 2
[0024] Carry out embodiment 1 repeatedly by the same steps as described, the difference is: step (4) makes soft material: add the ethanol that concentration is 60% in blueberry powder, step (5) low temperature granulation: keep the whole process of low temperature granulation The temperature is 48°C, and step (7) secondary low-temperature granulation: After the wet granulated medicine is completely dried at a low temperature of -3°C, the low-temperature granulation process is performed again at a temperature of 48°C.
Embodiment 3
[0026] Carry out embodiment 1 repeatedly by the same steps as described, the difference is: step (4) makes soft material: adding the ethanol that concentration is 70% in blueberry powder, step (5) low-temperature granulation: keep the whole process of low-temperature granulation The temperature is 28°C, and step (7) secondary low-temperature granulation: After the wet granulated medicine is completely dried at a low temperature of -5°C, the low-temperature granulation process is performed again at a whole temperature of 28°C.
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