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A kind of external gel for treating prone to skin diseases in tropical areas and preparation method thereof

A gel for external use, skin disease technology, applied in the field of traditional Chinese medicine, can solve the problems of difficult diagnosis, narrow application range, and difficult to accurately select drugs, etc., and achieve excellent antibacterial effect

Active Publication Date: 2018-04-27
广州植物耀素生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problems in this way are: ①The diagnosis is difficult to be clear, and it is difficult to accurately select drugs; ②The drug has a single function and narrow application range
Due to the wide application of hormones and antibiotic preparations, their actual drug effects cannot be reflected, often resulting in a helpless situation

Method used

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  • A kind of external gel for treating prone to skin diseases in tropical areas and preparation method thereof
  • A kind of external gel for treating prone to skin diseases in tropical areas and preparation method thereof
  • A kind of external gel for treating prone to skin diseases in tropical areas and preparation method thereof

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Experimental program
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Effect test

preparation example Construction

[0020] The preparation steps of the above-mentioned active pharmaceutical ingredients include: (1) take Sophora flavescens, Kochia scoparia, Toon root bark and add 8-15 times the amount of water, soak for 15-45min, extract 1-3 times, each time for 1.5-3.0 hours, filter After that, the combined filtrate is concentrated to the water extract with a relative density of 1: 0.8-1.2 for subsequent use; (2) get Cortex Phellodendri and Fructus Cnidii plus 6-10 times the amount of 60-90% ethanol, extract 1-3 times, each time Extract for 1-3 hours, recover ethanol, filter, combine the filtrates, concentrate to an alcohol extract with a relative density of 1:0.8-1.2, and set aside; (3) Take patchouli and Eucalyptus eucalyptus and add 10-15 times the amount of water, Soak for 0.5-2 hours, extract for 4-6 hours to obtain volatile oil; mix the above-mentioned water extract, alcohol extract, and volatile oil to obtain a combined medicinal solution for later use.

[0021] The preparation steps...

Embodiment 1

[0025] Prescription: Phellodendron 78.2, Cnidium 104.5, Sophora 157.3 Kochia 78.2, Toon root bark 78.2, Patchouli 55.5, Eucalyptus eucalyptus 111.8, Carbomer-94020, hydroxypropyl methyl 15 parts of sodium cellulose, 150 parts of propylene glycol, 200 parts of glycerin, 2 parts of anhydrous sodium sulfate, 2 parts of sodium hydroxide, 1 part of ethyl paraben, and an appropriate amount of distilled water.

[0026] Preparation method:

[0027] 1) Take Sophora flavescens, Kochia chinensis, and Toon root bark, add 12 times the amount of water, soak for 30 minutes, extract twice, 2.0 hours each time, filter, combine the filtrates, concentrate to 1:1, and set aside;

[0028] 2) Add 8 times the amount of 75% ethanol to Phellodendron Phellodendron and Fructus Cnidii, extract twice for 1.5 hours each time, recover ethanol, filter, combine filtrates, concentrate to 1:1, and set aside;

[0029] 3) Take patchouli and Eucalyptus eucalyptus, add 12 times the amount of water, soak for 1.5 ho...

Embodiment 2

[0033] prescription:

[0034] Phellodendron 65 parts, Cnidium 90 parts, Sophora flavescens 145 parts, Kochia chinensis 65 parts, Toon root bark 65 parts, Patchouli 45 parts, Eucalyptus eucalyptus 100 parts, Carbomer-94030 parts, hydroxypropyl methyl 30 parts of sodium cellulose, 170 parts of propylene glycol, 220 parts of glycerin, 3 parts of anhydrous sodium sulfate, 3 parts of sodium hydroxide, 2 parts of ethyl paraben, appropriate amount of distilled water.

[0035] Preparation method:

[0036] 1) Take Sophora flavescens, Kochia chinensis, and Toon root bark, add 15 times the amount of water, soak for 45 minutes, extract 3 times, each time for 1 hour, filter, combine the filtrates, concentrate to a relative density of 1:1.15, and set aside;

[0037] 2) Add 110 times the amount of 190% ethanol to Phellodendron Phellodendron and Fructus Cnidii, extract twice for 3 hours each time, recover ethanol, filter, combine filtrates, concentrate to 1:1.15, and set aside;

[0038] 3) Ta...

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Abstract

The invention discloses an external gel for treating incident skin diseases in a tropical zone and a preparation method of the external gel. The external gel is prepared from active medicinal ingredients and a gel substrate. The active medicinal ingredients are prepared from the following traditional Chinese medicines in parts by weight: 65-95 parts of golden cypress, 90-110 parts of fructus cnidii, 145-175 parts of radix sophorae flavescentis, 65-95 parts of belvedere fruits, 65-95 parts of cortex ailanithi, 45-70 parts of pogostemon cablin and 100-130 parts of encalyptus robusta. By using seven traditional Chinese medicines golden cypress, fructus cnidii, radix sophorae flavescentis, belvedere fruits, cortex ailanithi, pogostemon cablin and encalyptus robusta as main effective substances, the gel obtained by combining the gel substrate is mainly used for treating incident skin diseases in the tropical zone such as scrotitis, dermatitis and the like. Pharmacological researches verify that the gel prepared has excellent effects of inhibiting bacteria, diminishing inflammation, relieving itching and dispelling rash.

Description

technical field [0001] The invention relates to a medicine for treating prone to skin diseases in tropical areas and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] In my country, the southeast coastal provinces south of the Yangtze River, such as Zhejiang, Fujian, Guangdong, Hainan, Taiwan, and southern Jiangsu, southern Yunnan, and southwestern valleys with an altitude of less than 1,500 meters are classified as tropical regions, which belong to hot and humid climate, and its main characteristics are ① High temperature, long heat period and strong daily radiation; ②a lot of rain and high humidity; ③more thunderstorms and frequent typhoons. Dermatosis is one of the high incidence species in the tropics. Working in a hot and humid environment, due to a lot of sweating, the skin is continuously soaked in sweat, and skin diseases are prone to occur, such as boils, ringworm, prickly heat, scrotum dermatitis an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K9/06A61P17/00A61P31/04A61P29/00A61P17/04A61P15/00
CPCA61K9/0014A61K9/06A61K36/185A61K36/234A61K36/489A61K36/53A61K36/58A61K36/61A61K36/70A61K36/756A61K47/10A61K47/32A61K47/38A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 吕志平刘强
Owner 广州植物耀素生物科技有限公司