Acne-removing preparation

A preparation and acne technology, applied in the direction of medical preparations containing active ingredients, plant raw materials, antibacterial drugs, etc., can solve the problems of skin allergies, recurrences, redness, etc., to improve skin metabolism and improve redness Itching symptoms, skin metabolism promotion effect

Inactive Publication Date: 2015-04-29
郑华娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the external products used for acne removal on the market contain azelaic acid, cimetidine, benzoyl peroxide, adapalene, vitaminate, etc., and some external preparations made of antibiotic drugs, mainly Acne is treated by inhibiting oil secretion and accelerating the exfoliation of epidermal cutin. After using this type of product, the skin is prone to allergies, redness, and peeling. After stopping the drug, it is easy to relapse, forming a drug dependence, and most external products contain Hormone and mercury, lead and other harmful chemical components, acne is only temporary

Method used

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Experimental program
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Effect test

Embodiment 1

[0041] The preparation method of the present embodiment 1 anti-acne preparation is:

[0042] (1) 11.5% of Salvia miltiorrhiza extract, 8.5% of honeysuckle extract, 8% of Coptis chinensis extract, 5% of peach kernel extract, 2.5% of calamine extract and 0.7% of loquat leaf extract were dried and crushed to 42 meshes to obtain coarse powder;

[0043] (2) Put the coarse powder obtained in step (1) into a supercritical extraction kettle, add 1,3-butanediol 5%, deionized water 65%, β-glucan 2.7%, a-bisabolol 6% and propylparaben 1.5%, using CO 2 Supercritical fluid extraction, extraction temperature is 53.5°C, extraction pressure is 31Mpa, extraction time is 3.5 hours, CO 2 The flow rate is 17.5L / h; the obtained supercritical CO containing extract 2 The fluid is decompressed and analyzed to separate the extraction product, the separation temperature is 53.5°C, and the separation pressure is 11.5Mpa. The volatile active ingredients and fat-soluble active ingredients are collected...

Embodiment 2

[0045] The preparation method of the anti-acne preparation of present embodiment 2 is:

[0046] (1) Drying 3% of Salvia miltiorrhiza extract, 2% of honeysuckle extract, 1% of Coptis chinensis extract and 0.5% of loquat leaf extract by weight percentage, respectively, and crushing to 5 mesh to obtain coarse powder;

[0047] (2) Put the coarse powder obtained in step (1) into a supercritical extraction kettle, add 1% polyol, 90% deionized water, 0.5% β-glucan and 2% a-bisabolol, and use CO 2 Supercritical fluid extraction, extraction temperature is 32°C, extraction pressure is 12Mpa, extraction time is 1 hour, CO 2 The flow rate is 10L / h; the obtained supercritical CO containing extract 2 The fluid is decompressed and analyzed to separate the extraction product, the separation temperature is 32°C, and the separation pressure is 5Mpa, and the volatile active ingredients and fat-soluble active ingredients are collected to obtain an acne-removing preparation.

Embodiment 3

[0049] The preparation method of present embodiment 3 anti-acne preparation is:

[0050] (1) 20% of Salvia miltiorrhiza extract, 15% of honeysuckle extract, 15% of Coptis chinensis extract, 1% of peach kernel extract, 1% of calamine extract and 0.7% of loquat leaf extract were dried and crushed to 80 mesh, to obtain coarse powder;

[0051] (2) Put the coarse powder obtained in step (1) into a supercritical extraction kettle, add 2% glycerin, 40% deionized water, 2% β-glucan, 2% a-bisabolol, methyl chloride Mixture of isothiazolinones and phenoxyethanol 1.3% with CO 2 Supercritical fluid extraction, extraction temperature is 75°C, extraction pressure is 50Mpa, extraction time is 6 hours, CO 2 The flow rate is 25L / h; the obtained supercritical CO containing extract 2 The fluid is decompressed and analyzed to separate the extraction product, the separation temperature is 75°C, and the separation pressure is 18Mpa, and the volatile active ingredients and fat-soluble active ingr...

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Abstract

The invention relates to an acne-removing preparation which is prepared from the following components in percentage by weight: 3%-20% of a radix salviae milliorrhizae extract, 2%-15% of a honeysuckle extract, 1%-15% of a coptis chinensis extract, 0-10% of a peach kernel extract, 0-5% of a calamine extract, 0.5%-1% of a loquat leaf extract, 1%-10% of polyhydric alcohols, 40%-90% of deionized water, 0.5%-5% of beta glucan, 2%-10% of alpha-bisabolol and 0-3% of an antiseptic and antibiotic agent. The acne-removing preparation is capable of improving skin microcirculation ecological environment by stretching and shrinking pores, dissolving fat, removing scales and deeply conditioning the skin, removing skin inflammation, inhibiting bacterial growth, killing propionibacterium acnes, staphylococcus and the like, comprehensively improving the skin metabolism capacity and restoring the ecology system balance of the skin, so that acnes lose the basis of existence, the acnes are naturally eliminated to achieve the magical effect of treating both symptoms and root causes, and the skin metabolism is promoted by expelling toxins.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to an acne-removing preparation. Background technique [0002] Acne is a chronic skin inflammation that mostly occurs in adolescents. If it is not treated in time or prevented properly, it will leave scars that are difficult to heal for life, which will affect the appearance and make many young patients very distressed. At present, most of the external products used for acne removal on the market contain azelaic acid, cimetidine, benzoyl peroxide, adapalene, vitaminate, etc., and some external preparations made of antibiotic drugs, mainly Acne is treated by inhibiting oil secretion and accelerating the exfoliation of epidermal cutin. After using this type of product, the skin is prone to allergies, redness, and peeling. After stopping the drug, it is easy to relapse, forming a drug dependence, and most external products contain Hormone and mercury, lead and other harm...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P17/10A61P31/04A61K33/30
Inventor 郑华娟
Owner 郑华娟
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