Preparation method of collagen suture lines

A technology for collagen and sutures, applied in the field of production of collagen sutures, can solve the problems of not being widely used, poor cell compatibility, poor flexibility of guts, etc., and achieve scientific, reasonable and easy production methods. Knotting, the effect of reducing production costs

Inactive Publication Date: 2015-04-29
周峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Absorbable sutures can be made from gut, animal tendon, human hair, etc. The flexibility of gut is not good, and it is prone to antigen-antibody reaction
The quality of animal tendon suture is stable, the absorption is uniform, it can promote the proliferation of cells, and the cell compatibility is good, but it is easy to be absorbed prematurely in the body, so it cannot be widely used
Human hair sutures are more flexible and less compatible with cells, so they still need to be removed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0017] Embodiment: the collagen suture among the present invention is a kind of novel suture, is stripped out from beaver tail, and its preparation method and steps are:

[0018] (1) Select adult, healthy and lively beavers to extract collagen tail tendon.

[0019] After cleaning the adult, healthy and lively beavers that meet the requirements, quickly cut off their necks with a guillotine, lift up the tail, and put it upside down for 5 minutes. After the blood in the beaver's body is exhausted, cut off the tail along the base of the tail , Put it in 75% ethanol for disinfection, then peel off the tail skin with a peeler, soak it in warm water at 30 degrees for 1 to 2 minutes, and then quickly move it into a sterile room to extract the collagen tail tendon.

[0020] (2) Soak the extracted collagen tail tendons in 1% to 3% NaOH solution for 10 to 20 minutes to degrease.

[0021] (3) Carry out virus inactivation with 1 oml / L NaOH to the collagen tail tendons after degreasing, a...

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PUM

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Abstract

The invention relates to a preparation method of collagen suture lines, and belongs to the technical field of medical suture lines. The preparation method of the collagen suture lines comprises the following steps: stripping off a plurality of collagen tail tendons from the tail of a beaver, performing degreasing, viral inactivation, rinsing, dehydration, straightening, air drying, and screening on the collagen tail tendons, and performing oil tannage, washing, vacuum packaging and antiseptic disinfection on the collagen tail tendons which conform to requirements. The preparation method disclosed by the invention has the benefits that the production process is simple, the preparation method is scientific and reasonable, the rate of finished products is high, the collagen suture lines can be produced in batches, and the production cost of the collagen suture lines is lowered. The collagen suture lines which are prepared by the method disclosed by the invention have the advantage that the stability and the elasticity are good, the flexibility is high, the collagen suture lines are easy to knot, the tensile resistance is high, the collagen suture lines can be absorbed by human bodies, antigen-antibody reaction cannot be generated, needle holes and scars are not remained, sutures are smooth after the sutures are healed.

Description

Technical field: [0001] The invention relates to a method for preparing a suture, in particular to a method for preparing a collagen suture. Background technique: [0002] At present, there are two types of known medical sutures, one is non-absorbable medical sutures, such as nylon, polyester fiber, silk thread, etc., which have high strength and good stability, but cannot be absorbed by the body. Afterwards, it must be removed by surgery again, which will bring secondary pain to the patient. The other type is absorbable sutures, which overcome the disadvantages of non-absorbable sutures, and the sutures can be absorbed by the body after the wound has healed. Materials for absorbable sutures can be made from gut, animal tendon, human hair, etc., but gut has poor flexibility and is prone to antigen-antibody reactions. Animal tendon sutures are stable in quality, absorb evenly, can promote cell proliferation to a certain extent, and have good cell compatibility. However, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L17/10
Inventor 周峰王伟吕作文李强
Owner 周峰
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