A preparation with antibacterial, anti-inflammatory and analgesic functions and its preparation method

A preparation and functional technology, applied in the direction of anti-inflammatory agents, medical preparations containing active ingredients, antibacterial drugs, etc. good quality effect

Active Publication Date: 2017-04-12
贵州科学院贝科生物资源研究开发中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The research on guangzhigou catecha alone mainly focuses on the research on chemical components, clinical application research and crude drug identification, etc. There is little research on the medicinal material extract and its preparation products. Only patent application CN201210092331.3 discloses a The iron-coated gold extract with antitumor effect and its preparation method is to use the iron-coated gold water extract, alcohol extract or organic extract to treat mouse H 22 HCC and S 180 Sarcoma, there are no detailed reports on the antibacterial, anti-inflammatory and analgesic aspects of the preparation of the active ingredient extract of Guccia glabrata

Method used

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  • A preparation with antibacterial, anti-inflammatory and analgesic functions and its preparation method
  • A preparation with antibacterial, anti-inflammatory and analgesic functions and its preparation method
  • A preparation with antibacterial, anti-inflammatory and analgesic functions and its preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0027] Embodiment 1: the preparation of extract

[0028] Get 1.8kg of glaucous catechu branches and leaves to pulverize, and extract the volatile oil by steam distillation for subsequent use; the dregs are reflux extracted 3 times with 10 times the concentration of 65% ethanol, each time for 0.5 hour, the extract is filtered, the filtrates are combined, and then Add 8 times the amount of petroleum ether-60 for extraction, after layering, take the petroleum ether-60 layer and filter, recover the solvent from the filtrate, concentrate to make an extract with a relative density of 1.30 at 55°C, combine the extract and volatile oil to obtain Glycyrrhiza catechua extract.

Embodiment 2

[0029] Embodiment 2: the preparation of extract

[0030] Take 3.0 kg of G. glabrata branches and leaves and pulverize them, and extract the volatile oil by steam distillation for later use; the dregs are reflux extracted with 6 times the amount of 100% ethanol for 1.5 hours, the extract is filtered, and the filtrate is extracted by adding 6 times the amount of chloroform. After layering, take the chloroform layer and filter it, recover the solvent from the filtrate, concentrate it to make an extract with a relative density of 1.15 at 60°C, combine the extract and volatile oil to obtain the extract of C. glabrata.

Embodiment 3

[0031] Embodiment 3: the preparation of extract

[0032] Get 1.2kg of glaucous catechu branches and leaves, and extract the volatile oil by steam distillation for subsequent use; the dregs are reflux extracted twice with 80% ethanol at a concentration of 8 times, each time for 1 hour, the extract is filtered, and the filtrates are combined, and then Add 7 times the amount of chloroform for extraction, after layering, take the chloroform layer and filter, recover the solvent from the filtrate, concentrate it to make an extract with a relative density of 1.20 at 60°C, combine the extract and volatile oil to obtain the extract of C. .

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Abstract

The invention relates to a preparation having antibacterial, anti-inflammatory and analgesic functions and a preparation method of the preparation. The preparation is prepared from 1.2-3.5 parts by weight of berchemia polyphylla var.leioclada; and the preparation method comprises the following steps: grinding the branches and leaves of the berchemia polyphylla var.leioclada, and extracting volatile oil by virtue of a steam distillation method for later use; refluxing and extracting dregs with ethanol for 1-3 times, filtering an extracting solution, combining filtrates, then adding an organic solvent and extracting, layering and filtering an organic solvent layer, concentrating the filtrate into an extract, drying, and adding accessories and the volatile oil to prepare the required preparation. By adopting the branches and the leaves, the utilization rate of active ingredients of the berchemia polyphylla var.leioclada is greatly improved, and the preparation method is simple in production process; and the berchemia polyphylla var.leioclada or the composition preparation disclosed by the invention has good antibacterial, anti-inflammatory and analgesic functions, and is significant in curative effect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines and health care products, and in particular relates to an extraction method of active ingredients of C. glabrata, a preparation of C. glabrata and a production method thereof. Background technique [0002] Bechemia polyphylla Wall.exLaws.var.leioclada Hand.-Mazz. is a plant of the Rhamnaceae Bechemia genus, also known as iron clad gold, mouse ear and oolong root. Distributed in the southwest of China, it is a traditional medicinal material of the Miao people in Guizhou. Most of the roots, stems, and leaves are used as medicines. They are bitter in taste and flat in nature. [0003] The roots and leaves of guangzhigou catechu are used medicinally to regulate menstruation and activate blood circulation; the roots and seeds are often boiled in water to treat tuberculosis among Sichuan folks; the young leaves can be used as a substitute for tea. According to prior art reports, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/72A23L33/00A61P31/04A61P29/00
Inventor 贾强王芳梁明亮秦华军
Owner 贵州科学院贝科生物资源研究开发中心
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