A kind of preparation method of tetrafluoroborate spirocyclic ammonium salt
A technology of spiro tetrafluoroborate and fluoroborate, applied in organic chemistry and other directions, can solve problems such as unreported purification methods, affecting electrolyte performance, etc., and achieve the effects of convenient recycling and application, improving quality and performance, and reducing three wastes.
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[0038] The present invention provides a kind of preparation method of tetrafluoroboric acid spirocyclic quaternary ammonium salt, comprising the following steps:
[0039] 1) Put the alkali, fluoroborate, dihaloalkane, and cyclic amine in the reaction solvent, react at 50-90°C, cool down and filter after the reaction is completed, and remove the solvent from the filtrate;
[0040] In the preparation method of the spirocyclic quaternary ammonium tetrafluoroborate provided by the present invention, the base is preferably an inorganic base, more preferably one of lithium carbonate, sodium carbonate, potassium carbonate, lithium hydroxide, sodium hydroxide, and potassium hydroxide. one or more combinations. The molar ratio of cyclic amine to base is preferably 1:0.9 to 1:2, more preferably 1:1 to 1:1.1.
[0041] In the preparation method of the spirocyclic quaternary ammonium tetrafluoroborate provided by the present invention, the fluoroborate is preferably one or more combinatio...
Embodiment 1
[0062] Example 1: (tetrafluoroboric acid spiro-1,1-dipyrrolidinium salt)
[0063] In a 2000mL reactor, 500g of acetonitrile, 193.5g (1.4mol) of potassium carbonate, 146.8g (1.4mol) of ammonium fluoroborate, 177.8g (1.4mol) of 1,4-dichlorobutane, 100g (1.4mol) of ) Tetrahydropyrrole. Heat to 60-70°C and keep it warm for 50 hours. Cool down to room temperature, filter with suction, rinse the filter cake with 50 g of acetonitrile, and combine the filtrates to obtain an acetonitrile solution of the product. The filtrate was concentrated under reduced pressure, 600 g of ethanol and 1.0 g of 18-crown-6 were added for recrystallization, filtered, and vacuum-dried to obtain 229 g of the product. Melting point: 189.2 to 189.7. 1 H NMR (300MHz,D 2 O): δ=2.08~2.09(m,8H), 3.38~3.43(m,8H). 13 C NMR (75MHz, D 2 O): δ=21.67(CH 2 ),62.78(CH 2 ). 19 F NMR (376MHz, CDCl 3 ): δ=-151.95.
Embodiment 2
[0064] Example 2: (tetrafluoroborate spiro-1,1-dipyrrolidinium salt)
[0065] In a 2000mL reactor, 500g of acetonitrile, 193.5g (1.4mol) of potassium carbonate, 146.8g (1.4mol) of ammonium fluoroborate, 177.8g (1.4mol) of 1,4-dichlorobutane, 100g (1.4mol) of ) Tetrahydropyrrole. Heat to 60-70°C and keep it warm for 50 hours. Cool down to room temperature, filter with suction, rinse the filter cake with 50 g of acetonitrile, and combine the filtrates to obtain an acetonitrile solution of the product. The filtrate was concentrated under reduced pressure, and 600 g of ethanol was added for recrystallization, filtered, and vacuum-dried to obtain 230 g of the product.
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