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Pharmaceutical preparation for treating mental anxiety and application of pharmaceutical preparation

A technology of pharmaceutical preparations and Taibai ginseng, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, can solve problems such as insignificant therapeutic effects, large toxic and side effects of western medicines, and difficulty in calming down. Economic burden, short course of treatment, and the effect of less recurrence

Inactive Publication Date: 2015-06-03
王继委
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(3) Motility restlessness, restlessness, restlessness, irritability, and difficulty in calming down
Its purpose is to solve the problem of treating mental anxiety, overcoming the serious side effects of Western medicine, easy to repeat drug withdrawal, and insignificant therapeutic effect, so as to achieve the goal of treating both symptoms and root causes.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A pharmaceutical preparation for treating mental anxiety, which is prepared from the following raw materials in proportion by weight,

[0030] 35 parts of Taibai Ginseng, 35 parts of Shichangpu, 35 parts of Polygala, 35 parts of Epimedium, 30 parts of Poria,

[0031] 30 parts of psoralen, 30 parts of red peony root, 30 parts of Magnolia officinalis, 25 parts of Dannanxing, 25 parts of Centella asiatica,

[0032] 25 parts of Acanthopanax, 20 parts of Gorgon, 20 parts of Heartwort, 20 parts of daylily, 20 parts of Milletah,

[0033] 18 parts of Radix Paeoniae Alba, 18 parts of Noctilucia, 18 parts of Citrus aurantium, 18 parts of Sangjisheng, 15 parts of Dendrobium,

[0034] 15 parts of Anemarrhena, 15 parts of Sanleng, 10 parts of Alisma, 10 parts of Gardenia, 10 parts of Curcuma, and 5 parts of Suanzaoren.

[0035] Its preparation method is:

[0036] (1) Take Taibai ginseng, Shichangpu, polygala, epimedium, dannanxing, centella asiatica, huixincao, nocturnal vine, mu...

Embodiment 2

[0043] Acute toxicity test: 40 mice, half male and half female, weighing 30-40 g, were used for acute toxicity test. The mice were randomly divided into two groups, i.e. the control group and the administration group, 20 in each group, fasted for 12 hours before the experiment, and the administration group was given the Chinese patent medicine prepared in Example 1 of the present invention dissolved in water for intragastric administration. (Single administration dose of intragastric administration is 50g crude drug / kg), the control group was given the same amount of normal saline, administered twice a day, with an interval of 6 hours between administrations, observed continuously for two weeks after administration, and recorded the Toxic reactions and deaths. The results of the experiment showed that compared with the control group, there was no significant difference in the mice after administration. After 14 days of continuous observation in the experiment, the general cond...

Embodiment 3

[0046] clinical information

[0047] The 102 cases were all selected from outpatient clinics. The selected patients were all in line with the diagnostic criteria of CCMD-3 and DSM-IV generalized anxiety disorder, with an anxiety scale (HAMARS) score ≥ 18, no physical disease and brain organic disease, and excluded Other mental diseases are divided into treatment group and control group according to different treatments:

[0048] Treatment group: 51 cases, 24 males and 27 females, with an average age of 35 years, the youngest was 27 years old, and the oldest was 54 years old; the average course of disease was 9 months.

[0049] Control group: 51 cases, 23 males and 28 females, with an average age of 35 years, the youngest was 26 years old, and the oldest was 53 years old; the average course of disease was 9 months.

[0050] There was no significant difference in the general data between the two groups after statistical processing (chi-square test and t-test) (P>0.05), and they...

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Abstract

The invention relates to a pharmaceutical preparation for treating mental anxiety, which is prepared from the following raw materials: david woodbetony rhizome, rhizoma acori graminei, polygala roots, herba epimedii, poria cocos, fructus psoraleae, radix paeoniae rubra, cortex magnoliae officinalis, arisaema cum bile, centella, acanthopanax roots, semen euryales, rhodobryum roseum, hemerocallis citrina baroni, caulis spatholobi, radix paeoniae alba, tuber fleeceflower stem, fructus aurantii immaturus, parasitic loranthus, dendrobium nobile, rhizoma anemarrhenae, rhizoma sparganii, rhizoma alismatis, gardenia, radix curcumae and spine date seeds. The pharmaceutical preparation can treat both symptoms and root causes of mental anxiety, has no side effect, and is low in cost, simple and convenient to prepare, and wide in application prospect.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmaceutical preparations, and in particular relates to a pharmaceutical preparation for treating mental anxiety and its application. Background technique [0002] Anxiety disorder, also known as anxiety neurosis, is the most common type of neurosis, and its main feature is the experience of anxiety. It can be divided into two forms: chronic anxiety (generalized anxiety) and acute anxiety attacks (panic disorder). The main manifestations are: nervousness and worry without a clear objective object, restlessness, and autonomic symptoms (palpitations, hand tremors, sweating, frequent urination, etc.). The clinical manifestations of anxiety disorders: 1 Chronic anxiety (generalized anxiety) (1) Emotional symptoms In the absence of obvious incentives, patients often appear excessive worry, nervousness and fear that do not match the actual situation. object and content. The pat...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P25/22
Inventor 王继委孙辉
Owner 王继委
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