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A moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom

A composite, biomimetic film technology, applied in the field of daily care products, can solve the problems of increasing, not easy to mix and directly absorb, stability and use function is not very prominent, achieve high affinity, improve skin roughness, superior moisturizing effect

Active Publication Date: 2017-10-27
HUAANTANG BIOTECH GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for characteristic dermatitis (i.e. lesion-type skin), there are varying degrees of defects in the epidermal barrier function and the stratum corneum (this characteristic feature can be measured by skin tester ~ VISIA CK, Tewameter TM300, Cornemeter and other instruments to measure the epidermal water content, Skin moisture loss rate, skin elasticity and other content change judgment), this kind of consumer groups are also increasing, and allergic reactions have become a public problem
At present, ceramide or liposome is often used as a single substance in the industry to directly add to the formula. Because it is a fat-soluble substance, it is not easy to mix and absorb directly in the cosmetic formula, resulting in not very outstanding performance in terms of stability and use function.

Method used

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  • A moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom
  • A moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom
  • A moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The preparation method of a skin biomimetic membrane liquid crystal complex of the present embodiment, the specific preparation steps are as follows:

[0037] (1) Prepare the epidermal lipid complex according to the following ingredients and contents:

[0038]

[0039] Add A1-A4 into the water phase pot, stir while heating until the temperature is 45-50°C, keep warm for later use, and obtain phase A; add B1-B8 into the vacuum emulsification pot in turn, stir slowly and heat until completely dissolved and uniform Finally, keep the temperature at 45°C for later use to obtain phase B; turn on the vacuum of phase B to 0.02-0.05Mpa, suck phase A into phase B, then cool and crystallize naturally while stirring, and obtain the epidermal lipid complex HAT~MIX1;

[0040] (2) According to the following ingredients and content ingredients and preparation of epidermal biomimetic membrane liquid crystal composite:

[0041]

[0042]

[0043] Add A1 into the water phase pot,...

Embodiment 2

[0046] The preparation method of a skin biomimetic membrane liquid crystal complex of the present embodiment, the specific preparation steps are as follows:

[0047] (1) Prepare the epidermal lipid complex according to the following ingredients and contents:

[0048]

[0049] Add A1-A4 into the water phase pot, stir while heating until the temperature is 45-50°C, keep warm for later use, and obtain phase A; add B1-B8 into the vacuum emulsification pot in turn, stir slowly and heat until completely dissolved and uniform Finally, keep the temperature at 45°C for later use to obtain phase B; turn on the vacuum of phase B to 0.02-0.05Mpa, suck phase A into phase B, then cool and crystallize naturally while stirring, and obtain the epidermal lipid complex HAT~MIX1;

[0050] (2) According to the following ingredients and content ingredients and preparation of epidermal biomimetic membrane liquid crystal composite:

[0051]

[0052]

[0053]Add A1 into the water phase pot, ...

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Abstract

The invention belongs to the technical field of daily care products, and discloses a moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom. The core components of the moisturizing repair composition and the skin biomimetic membrane liquid crystal complex are ceramide, phytosphingosine, cholesterol, lauroyl glutamate, squalane, myristyl alcohol, cetearyl alcohol, alcohol Acine, Glycine and Hydroxyproline. The present invention develops a special epidermal biomimetic membrane through the combination of various raw materials and utilizing the formation mechanism of lamellar liquid crystals, which can form lamellar liquid crystals similar to the lipid layer between corneocytes, thereby Play its role in protecting the skin and improving the condition of the skin.

Description

technical field [0001] The invention belongs to the technical field of daily care products, and in particular relates to a moisturizing and repairing composition and an epidermis biomimetic membrane liquid crystal complex constructed therefrom. Background technique [0002] At present, there are many types of moisturizing and repairing cosmetics on the market, mainly based on small molecular polyols (such as: glycerin, 1,3 butanediol, propylene glycol, etc.), sodium lactate, betaine, and polymer film-forming substances (hyaluronic acid, polysaccharides, etc.) etc.) as the main body, these substances are easy to absorb and metabolize, and they are not outstanding in terms of long-term water locking and moisturizing and skin barrier repair. From the perspective of the mechanism of action, the above moisturizing and repairing effects are mainly due to the combination of hydrophilic groups and hydrophilic lipids on the surface of the cuticle to form a surface association form (s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/63A61K8/42A61K8/92A61K8/02A61Q19/00
Inventor 何廷刚艾勇朱思阳艾艳邵珠广陈洪黄垂凡
Owner HUAANTANG BIOTECH GRP CO LTD
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