Pharmaceutical composition for treating senile acute upper gastrointestinal hemorrhage

Abstract

The invention discloses a pharmaceutical composition for treating senile acute upper gastrointestinal hemorrhage, used for solving the treatment problem of senile gastrorrhagia. The pharmaceutical composition is characterized by being prepared from the following medicinal raw materials: parabarium micranthum, the bark of eucommia, plum blossom, timonius arboreus, harlequin glorybower leaf, buckeye, delavay raspberry herb, sealwort, unpleasant swallowwort herb, fingered citron, oxhide gelatine and poncirus bark. Clinical experiments prove that the pharmaceutical composition disclosed by the invention has good curative effect and higher safety for treating senile gastrorrhagia; and therefore, the pharmaceutical composition is worthy of being clinically applied and popularized.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating acute upper blood disappearance in the elderly. Background technique [0002] Upper gastrointestinal bleeding (UGIB), referred to as upper blood loss, is one of the common acute and severe diseases in gastroenterology. If it is not diagnosed quickly and treated in time, the fatality rate can reach more than 10%. The current emergency treatment methods are mostly: add 8 mg of norepinephrine to 100 mL of normal saline, put it in the refrigerator to cool down to 3°C-4°C, and take it 3-4 times a day orally or inject it through a gastric tube. This method is based on the contraction of surface capillaries, but the effect of promoting surface coagulation is not satisfactory. Therefore, it has also been reported in clinical reports that external hemostatic drugs such as Yunnan Baiyao are added to iced saline to enhance the hemostatic ...

AI Technical Summary

Problems solved by technology

Difficulty in treatment lies in: ① Elderly patients are prone to relapse after treatment due to decline in body function, reduced heart pumping volume, and decreased blood volume in the whole body, resulting in decreased blood supply to the gastric mucosa and ulcers and various lesions; Patients may take a variety of drugs for a long time, and the medication is complicated, such as anticoagulant drugs, glucocorticoids, and non-steroidal anti-inflammatory drugs, which will increase the possibility of gastric mucosal damage due to increased gastric acid secretion, and increase the difficulty of hemostasis ; ③Because it is often accompanied by a variety of chronic diseases, especially with heart, brain, kidney and other important organ diseases, the application of hemostatic drugs including Yunnan Baiyao orally will change the fragile blood coagulation balance, and the hypercoagulable state will lead to the occurrence of cardiovascular and cerebrovascular accidents

[0004] Based on the above reasons, when upper gastrointestinal bleeding occurs in clinical elderly patients, especially gastric bleeding, the medication is limited, and it is easy to cause complications such as aspiration pneumonia and cardiovascular and cerebrovascular accidents, and the recurrence rate of bleeding is high.

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