Pharmaceutical composition for treating senile acute upper gastrointestinal hemorrhage

A composition and drug technology, applied in the direction of drug combination, digestive system, blood diseases, etc., can solve problems such as aspiration pneumonia, cardiovascular and cerebrovascular accidents, increased difficulty in hemostasis, easy recurrence, etc., to relieve stress stimulation and advanced nervous system The effect of activity disorder, reducing the secondary crisis of cardiovascular and cerebrovascular diseases, and reducing the incidence of adverse reactions

Inactive Publication Date: 2015-08-19
孙佳文
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Difficulty in treatment lies in: ① Elderly patients are prone to relapse after treatment due to decline in body function, reduced heart pumping volume, and decreased blood volume in the whole body, resulting in decreased blood supply to the gastric mucosa and ulcers and various lesions; Patients may take a variety of drugs for a long time, and the medication is complicated, such as anticoagulant drugs, glucocorticoids, and non-steroidal anti-inflammatory drugs, which will increase the possibility of gastric mucosal damage due to increased gastric acid secretion, and increase the difficulty of hemostasis ; ③Because it is often accompanied by a

Method used

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  • Pharmaceutical composition for treating senile acute upper gastrointestinal hemorrhage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1, the weight ratio of raw materials: Eucommia ulmoides vine 20g, plum blossom 12g, stinky phoenix phoenix 12g, sunflower seed 15g, barb thorn 15g, eucommia ulmoides 15g, sealwort 15g, laojunxu 15g, sea sycium 15g, yellow gelatin 12g , Bergamot 2g, Hovenia 20g

[0029] The preparation method of Example 1 is: mix Eucommia ulmoides vine, Eucommia ulmoides, plum blossoms, sea squid, stinky phoenix tree, sycamore, barb thorn, sealwort, old gentleman's beard, bergamot, yellow gelatin (crushed), and hovenia ruthenium, add water and decoct Boil, take the filtrate after 30 minutes, add water to the dregs and continue decocting for 20 minutes, then take the filtrate, combine the two filtrates, concentrate under reduced pressure, freeze-dry, crush through a 100-mesh sieve, and pack. The above-mentioned dosage is for one day and is taken in two divided doses.

Embodiment 2

[0030] Example 2, the weight ratio of raw materials: 10 parts of eucommia ulmoides, 3 parts of plum blossoms, 3 parts of phoenix phoenix, 12 parts of scorpion seeds, 12 parts of barb thorns, 12 parts of Eucommia ulmoides, 12 parts of Polygonatum, 12 parts of Laojunxu , Hercynium 12 parts, Yellow Gelatin 3 parts, Bergamot 1 part, Hovenia 10 parts.

Embodiment 3

[0031] Example 3, the weight ratio of raw materials: 20 parts of eucommia ulmoides, 12 parts of plum blossoms, 12 parts of Stinky Indus, 15 parts of Su Luozi, 15 parts of barb thorns, 15 parts of Eucommia ulmoides, 15 parts of Polygonatum, and 15 parts of Laojunxu , Hercynium 15 parts, Yellow Gelatin 12 parts, Bergamot 2 parts, Hovenia 20 parts

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Abstract

The invention discloses a pharmaceutical composition for treating senile acute upper gastrointestinal hemorrhage, used for solving the treatment problem of senile gastrorrhagia. The pharmaceutical composition is characterized by being prepared from the following medicinal raw materials: parabarium micranthum, the bark of eucommia, plum blossom, timonius arboreus, harlequin glorybower leaf, buckeye, delavay raspberry herb, sealwort, unpleasant swallowwort herb, fingered citron, oxhide gelatine and poncirus bark. Clinical experiments prove that the pharmaceutical composition disclosed by the invention has good curative effect and higher safety for treating senile gastrorrhagia; and therefore, the pharmaceutical composition is worthy of being clinically applied and popularized.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating acute upper blood disappearance in the elderly. Background technique [0002] Upper gastrointestinal bleeding (UGIB), referred to as upper blood loss, is one of the common acute and severe diseases in gastroenterology. If it is not diagnosed quickly and treated in time, the fatality rate can reach more than 10%. The current emergency treatment methods are mostly: add 8 mg of norepinephrine to 100 mL of normal saline, put it in the refrigerator to cool down to 3°C-4°C, and take it 3-4 times a day orally or inject it through a gastric tube. This method is based on the contraction of surface capillaries, but the effect of promoting surface coagulation is not satisfactory. Therefore, it has also been reported in clinical reports that external hemostatic drugs such as Yunnan Baiyao are added to iced saline to enhance the hemostatic ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P7/04A61P1/00
Inventor 孙佳文
Owner 孙佳文
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