Pharmaceutical composition for treating dairy cattle mastitis

A composition and drug technology, applied in the field of traditional Chinese veterinary medicine, can solve the problems of unclean environment, infrequent replacement of rubber tubes, and non-sterilization, etc., and achieve the effects of simple production process, less drug resistance, and less toxic and side effects

Active Publication Date: 2015-09-23
山东禹泽药康产业技术研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The common ones are that the cowshed is dusty, the environment is not clean, not disinfected or not disinfected according to the regulations; the cow bed is wet and dirty, and it is not washed and disinfected in time; Infrequent replacement of rubber tubes, failure to clean and disinfect the milking machine according to regulations, and unclean vacuum pump regulators can cause bacterial growth and increase the chance of cows being infected with mastitis

Method used

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  • Pharmaceutical composition for treating dairy cattle mastitis

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Prescription: Dandelion 200g, Prunella vulgaris 150g, Passepartout 120g, Leulu 120g, Bergamot 120g, Saxifraga 120g, Sage 120g, Fotanmu 100g, Viola 100g, Dijincao 100g, Buckwheat seven 100g, White grass 60g.

[0053]Preparation method: take bergamot and sage, add water with 8 times the weight of medicinal materials, then add sodium chloride with 15% water weight, distill and extract for 4 hours, receive volatile oil, add β-cyclodextrin and β-cyclodextrin with 5 times the weight of volatile oil Take 15 times the weight of volatile oil in water, grind for 2 hours with a colloid mill, dry at low temperature, and crush; To turn white grass, add water 12 times the weight of the medicinal material, add bergamot and sage residue after steam distillation, heat and extract twice, each time for 1 hour, filter, and the filtrate is concentrated under reduced pressure to a relative density of 1.30~ 1.35 (measured at 60°C) thick paste, dried under reduced pressure, crushed; take the ...

Embodiment 2

[0055] Prescription: Dandelion 100g, Prunella vulgaris 75g, Passepartout 60g, Leulu 60g, Bergamot 60g, Saxifraga 60g, Sage 60g, Fotanmu 50g, Viola chinensis 50g, Dijincao 50g, Buckwheat seven 50g, turn White grass 30g.

[0056] Preparation method: take bergamot and sage, add water of 8 times the weight of medicinal materials, add sodium chloride of 15% of the weight of water, distill and extract, receive 2 times the distillate, and set aside; take dandelion, Prunella vulgaris, Passepartout, Leulu, saxifrage, fotanmu, zihuadiding, dijincao, buckwheat seven, and white grass, add water 12 times the weight of the medicinal materials, add bergamot and sage residues after steam distillation, heat and extract 2 times, 1 hour each time, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.05-1.10 (measured at 60°C), add bergamot and sage distillate, mix well, filter, add 0.5% of the volume of the mixture Wen-80, 3g sodium benzoate, 5g sodium citrate,...

Embodiment 3

[0058] Prescription: 600g of water-soluble active parts, 100g of alcohol-soluble active parts

[0059] Preparation method: Take the above-mentioned effective parts, mix well, and get ready.

[0060] Note: Prepare 200 parts of dandelion, 150 parts of Prunella vulgaris, 120 parts of Passepartout, 120 parts of saxifrage, 100 parts of fotanmu, 100 parts of Viola chinensis, 100 parts of Dijincao, 100 parts of buckwheat seven, 60 parts of Fenbai Cao. Add water 10 times the weight of the medicinal materials, heat and boil for extraction twice, each time for 2 hours, filter, concentrate the filtrate under reduced pressure to a relative density of 1.10-1.15 (measured at 60°C), and spray dry to obtain. The effective part is tested according to the determination method under the items of Dandelion, Prunella vulgaris, and Passepartout in the 2010 edition of the Pharmacopoeia of the People's Republic of China. It contains 0.12% of caffeic acid, 0.117% of rosmarinic acid, and 0.12% of Pass...

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Abstract

The invention discloses a pharmaceutical composition for treating dairy cattle mastitis, and belongs to the field of traditional Chinese veterinary medicine. The pharmaceutical composition is characterized in that dandelion, prunella vulgaris, liquidambar formosana hance, uniflower swisscentaury root, fingered citron, saxifraga stolonifera, sage, polygonum chinense, Chinese violet, humifuse euphorbia herb, fagopyrum cymosum and potentilla discolor are mixed in proportion according to pharmaceutical taste, through extraction and refinement, pharmaceutical adjuncts are added, and the raw materials are prepared into corresponding mixtures and granules through a conventional method. The pharmaceutical composition has the good effect of treating dairy cattle mastitis. The pharmaceutical composition is good in clinical application effect, low in cost and free of residues, is made of pure Chinese drug preparations, and has the good market prospects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese veterinary medicine, and in particular relates to a pharmaceutical composition for treating cow mastitis, a preparation method and application of the composition. Background technique [0002] Dairy mastitis is an important disease that endangers dairy farming. According to reports, the annual cost of mastitis per cow in the United States is about 200 US dollars, and the annual loss of the US dairy industry due to mastitis reaches 2 billion US dollars. In my country, the annual loss of milk production due to mastitis is about 1 2003 600 yuan per cow. The annual economic loss caused by mastitis is 15045 billion yuan. The invasion of pathogenic microorganisms into the milk pool through the nipple is an important reason for mastitis. Pathogenic microorganisms that cause mastitis in dairy cows include bacteria, mycoplasma, fungi, and viruses, among which Staphylococcus aureus, Streptococcus agala...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61P15/14
Inventor 代龙刘国飞
Owner 山东禹泽药康产业技术研究院有限公司
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