Method for preparing depression-relieving and soothing tablets

A satiating and depression-relieving technology, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, and devices that make drugs into special physical or ingestible forms. It can solve the problems of long operation time, large volume of extraction solvent, and unfavorable industrial Problems such as the application of large-scale production, to achieve the effect of shortening the extraction time and improving the extraction efficiency

Inactive Publication Date: 2015-10-07
NANJING HAICHANG CHINESE MEDICINE GRPCO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The patent number is 201110405141.8 A medicine for treating depression and its preparation method and its application discloses the preparation method. Since the extraction method used in this pate

Method used

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Examples

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Example Embodiment

[0039] Example 1

[0040] A preparation method of Jieyu Shunxin Tablets includes the following steps:

[0041] Step 1: Preparation of raw materials: 40 parts of Danshen, 8 parts of Bupleurum, 4 parts of Coptis, 12 parts of Turmeric, 8 parts of Polygala, 8 parts of Shichangpu, 12 parts of keel, 12 parts of oysters, 12 parts of Qingzhushi;

[0042] Step 2: Alcohol extraction: mix the raw materials in step one and add 80% ethanol solution, extract 3 times, each time the ethanol extraction time is 1.5h, the extraction temperature is 75℃, after the extraction is completed The extract is filtered through a 200-mesh sieve, and the filter residue is discarded;

[0043] Step 3: Collecting the paste: Concentrate the filtrate obtained in Step 2 under reduced pressure to an extract with a relative density of 1.25, and the conditions for concentration under reduced pressure are: the vacuum degree is -0.08MPa, the vapor pressure is not greater than 0.04MPa, and the temperature is 70°C;

[0044] Ste...

Example Embodiment

[0047] Example 2

[0048] A preparation method of Jieyu Shunxin Tablets includes the following steps:

[0049] Step 1: Preparation of raw materials: 20 parts of Danshen, 4 parts of Bupleurum, 2 parts of Coptis, 8 parts of Turmeric, 4 parts of Polygala, 4 parts of Shichangpu, 8 parts of keel, 8 parts of oysters, 8 parts of Qingzhushi;

[0050] Step 2: Alcohol extraction: mix the raw materials in step one and add 60% ethanol solution, extract 3 times, each time the ethanol extraction time is 1h, the extraction temperature is 65℃, after the extraction is completed, it will be extracted Filter the liquid through a 200-mesh sieve and discard the filter residue;

[0051] Step 3: Collecting paste: Concentrate the filtrate obtained in Step 2 under reduced pressure to an extract with a relative density of 1.2. The conditions for vacuum concentration are: vacuum degree is -0.06MPa, vapor pressure is not greater than 0.04MPa, and temperature is 70°C;

[0052] Step 4: Prepare extract powder: use s...

Example Embodiment

[0055] Example 3

[0056] A preparation method of Jieyu Shunxin Tablets includes the following steps:

[0057] Step 1: Preparation of raw materials: 30 parts of Danshen, 6 parts of Bupleurum, 3 parts of Coptis, 10 parts of Turmeric, 6 parts of Polygala, 6 parts of Shichangpu, 10 parts of keel, 10 parts of oyster, 10 parts of Qingzhushi;

[0058] Step 2: Alcohol extraction: mix the raw materials in step one and add 70% ethanol solution, extract 3 times, each time the ethanol extraction time is 1.25h, the extraction temperature is 70℃, after the extraction is completed The extract is filtered through a 200-mesh sieve, and the filter residue is discarded;

[0059] Step 3: Collecting the paste: Concentrate the filtrate obtained in Step 2 under reduced pressure to an extract with a relative density of 1.23. The conditions for vacuum concentration are: vacuum degree -0.07MPa, vapor pressure not greater than 0.04MPa, and temperature 70°C;

[0060] Step 4: Prepare extract powder: use spray-d...

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Abstract

The invention discloses a method for preparing depression-relieving and soothing tablets. The method includes a first step, preparing raw materials; a second step, extracting alcohol; a third step, collecting extracts; a fourth step, preparing extract powder; a fifth step, granulating the extract powder; a sixth step, compressing tablets. The method has the advantages that anti-depression effects can be realized by water-soluble components and fat-soluble components in herbal medicine in prescription; the ethyl alcohol with certain concentration is used as an extract solvent, accordingly, the water-soluble components and the fat-soluble components with the anti-depression effects in the prescription can be comprehensively extracted, and the method can be used for producing the depression-relieving and soothing tablets on a large scale during industrial mass production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method of Jieyu Shunxin Tablet. Background technique [0002] In modern life, the incidence of depression is high, and the causes of the disease are various. Reasons such as mental stress, diet, and sleep cause people to experience symptoms such as depression, pessimism, and lack of initiative. In severe cases, they will appear world-weary and suicidal. The drug treatment in the prior art generally adopts chemical drugs and Chinese patent medicines. Chemical drugs are highly targeted, but have large side effects, especially many potential hazards are not easy to be noticed in the short term. It has been continuously improved, but it is still unavoidable to avoid other side effects in the clinical treatment process. [0003] At the same time, as traditional Chinese medicine is becoming more and more widely known, the concept of using traditional Chinese ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/20A61P25/24A61J3/10A61K35/618A61K35/02A61K33/26
Inventor 蔡宝昌王彬金俊杰范孟雪黄雨婷陈林伟秦昆明王玉
Owner NANJING HAICHANG CHINESE MEDICINE GRPCO LTD
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