Medicine for preventing and treating non-alcoholic steatohepatitis and preparation method of medicine

A steatohepatitis, non-alcoholic technology, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems that have not yet made breakthroughs and unsatisfactory curative effects, and achieve prevention and treatment. Alcoholic steatohepatitis, improvement of fat variation, and effect of lowering blood lipids

Inactive Publication Date: 2015-11-25
DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to reports, most of the medicines for the treatment of non-alcoholic steatohepatitis are based on clearing away heat and dampness. The method of clearing away heat and dampness is adopted or on the basis of clearing away heat and dampness, some medicines for promoting blood circulation and removing blood stasis are added, but the curative effect is not satisfactory. Breakthrough progress has not yet been made, and there is no recognized cure drug at home and abroad so far

Method used

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  • Medicine for preventing and treating non-alcoholic steatohepatitis and preparation method of medicine
  • Medicine for preventing and treating non-alcoholic steatohepatitis and preparation method of medicine
  • Medicine for preventing and treating non-alcoholic steatohepatitis and preparation method of medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0231] Embodiment 1 capsule

[0232] Take 100 g of berberine and 100 g of puerarin as active ingredients, add dextrin as an auxiliary material, and prepare capsules according to a conventional process.

Embodiment 2

[0233] Example 2 tablet

[0234] Take 100 g of berberine and 50 g of puerarin as active ingredients, add starch as an auxiliary material, and press into tablets according to a conventional process to prepare tablets.

Embodiment 3

[0235] Embodiment 3 granules

[0236] Take 100 g of berberine and 800 g of puerarin as active ingredients, add starch as an auxiliary material, and prepare granules according to a conventional process.

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Abstract

The invention belongs to the field of Chinese herbal preparations, and specifically relates to a medicine for preventing and treating non-alcoholic steatohepatitis and a preparation method of the medicine. According to the medicine, puerarin and berberine are taken as active ingredients, and further, baicalin is selected as the active ingredient. The medicine is obvious in effect in improving hepatic tissue pathology, in particular for lipid droplet, also has large influences on transaminase, and basically achieves the effects of improving NASH dyslipidemia and actively regulating blood fat. The preparation method has good application prospect and great economic benefit for preparing the medicine for preventing and treating non-alcoholic steatohepatitis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a medicine for preventing and treating nonalcoholic steatohepatitis and a preparation method thereof. Background technique [0002] In recent years, due to changes in the diet structure and lifestyle of the masses, the incidence of non-alcoholic fatty liver disease (NAFLD) has continued to rise, and has gradually replaced hepatitis B virus as the main cause of chronic liver disease in my country. Therefore, the prevention and treatment of NAFLD is not only A medical problem has become a social problem. Therefore, it is imperative to actively do a good job in the prevention and treatment of NAFLD. [0003] Non-alcoholic fatty liver disease (NAFLD) is a metabolic stress-induced liver injury closely related to insulin resistance (IR) and genetic susceptibility. Its pathological changes are similar to those of alcoholic liver disease (ACD). Histor...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4375A61P1/16A61K31/352
Inventor 李军祥王允亮
Owner DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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