One-pot preparation of 2-bromo-9,9-diphenylfluorene

Abstract

The one-pot method for preparing 2-bromo-9,9-diphenylfluorene belongs to the technical field of organic synthesis, and comprises the following steps: (1); (2). The reaction of the present invention can be completed in one reactor, especially the chlorination reaction, without the need to separate the intermediate product, and directly add the system reactant and catalyst to carry out the subsequent reaction in which the chlorine atom is replaced by the benzene ring. The whole operation is simple and the process is reliable. , suitable for amplification; in addition, the catalyst used in the present invention can effectively reduce side reactions, improve product yield, reaching more than 90%, and because it is a solid catalyst, it can be separated by filtration after the reaction, which simplifies the post-treatment process.

Description

technical field

[0001] The invention belongs to the technical field of organic synthesis, and in particular relates to the preparation of 2-bromo-9,9-diphenylfluorene by a one-pot method. Background technique

[0002] Fluorene and its derivatives have the characteristics of a large conjugated system in the molecule, a rigid planar biphenyl structure, a wide energy gap, a high luminous efficiency, and easy modification of the structure, making them widely used in electroluminescent materials. , solar cell materials and other fields have a wide range of applications.

[0003] Dehydration reaction of tertiary alcohols with aromatic rings, Chang, Shun Li et al. (Journal of Organic Chemistry, 75(12), 4004-4013, 2010), Kim, Bok Yeong et al. (Repub. Korean Kongkae Taeho Kongbo, 2010006072), Seok, Hwan et al. (U.S.Pat.20090200928) and Lee, Seok-Jong et al. (U.S.Pat.20040157084) proposed trifluoromethanesulfonic acid and sulfuric acid as dehydrating agents, respectively. Trifluorom...

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