Descurainia sophia total-flavone tablets for relieving cough, eliminating phlegm and relieving asthma

A technology for relieving cough and expectorating phlegm from Nanting Lizi is applied in the field of medicine and achieves the effects of convenient use, scientific and rational formulation, and huge economic and social benefits.

Inactive Publication Date: 2015-12-16
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are no Chinese patent medicine preparations in the market that use the total flavonoids of Tinglizi as raw materials, including tablets, capsules, injections, drops, oral liquids, pills and ointments, etc. Public reports on traditional Chinese medicine preparations divided into raw materials, as well as effective preparations for eliminating phlegm, relieving cough, and relieving asthma

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] In the specific implementation of the present invention, it can also be calculated by the following weight percentages: β-cyclodextrin 45.5-46%, maltodextrin 36.5-37%, xylitol 1.7-1.9%, magnesium stearate 1.1-1.2% and It is made of 13.5-14% total flavonoids of Tinglizi chinensis, among which, the total flavonoids of Tinglizizi chinensis, 1 / 4 of β-cyclodextrin and 1 / 3 of maltodextrin are mixed together, and the concentration is prepared with distilled water. 1.2g / mL mixed solution, the mixed solution is spray-dried to obtain powder, add xylitol, magnesium stearate and the remaining 3 / 4 of β-cyclodextrin, 2 / 3 of maltodextrin to the powder, press Flakes, Serve as Tinglizi Total Flavonoids Tablets.

Embodiment 2

[0017] In the specific implementation of the present invention, it can also be calculated by the following weight percentages: β-cyclodextrin 47.5-48.5%, maltodextrin 32.5-34%, xylitol 2.1-2.4%, magnesium stearate 0.8-0.9% and It is made of 15.5-17% total flavonoids of Tinglizi chinensis, among which, the total flavonoids of Tinglizizi chinensis, 1 / 4 of β-cyclodextrin and 1 / 3 of maltodextrin are mixed together, and the concentration is prepared with distilled water. 1.2g / mL mixed solution, the mixed solution is spray-dried to obtain powder, add xylitol, magnesium stearate and the remaining 3 / 4 of β-cyclodextrin, 2 / 3 of maltodextrin to the powder, press Flakes, Serve as Tinglizi Total Flavonoids Tablets.

Embodiment 3

[0019] In the specific implementation of the present invention, it is calculated by the following weight percentage: 47% of β-cyclodextrin, 35% of maltodextrin, 2% of xylitol, 1% of magnesium stearate and 15% of total flavonoids of Tinglizi In which, the total flavonoids of Tinglizi chinensis, 1 / 4 of β-cyclodextrin and 1 / 3 of maltodextrin were mixed together, and distilled water was used to prepare a mixed solution with a concentration of 1.2g / mL, and the mixed solution was subjected to Spray drying to obtain powder, add xylitol, magnesium stearate and remaining 3 / 4 of β-cyclodextrin, 2 / 3 of maltodextrin to the powder, and press it into tablets to obtain the total flavonoids of Tinglizi piece.

[0020] The total flavonoids of Tinglizi described in the above examples are the same as the summary of the invention and will not be repeated.

[0021] The present invention follows the characteristics of traditional Chinese medicine and Chinese herbal decoction pieces, and according ...

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PUM

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Abstract

The invention relates to descurainia sophia total-flavone tablets for relieving cough, eliminating phlegm and relieving asthma. The problem of preparation of cough-relieving, phlegm-eliminating and asthma-relieving drugs by utilizing descurainia sophia total flavones as a raw material can be effectively solved. The descurainia sophia total-flavone tablets are prepared from, by weight, 45-49% of beta-cyclodextrin, 33-37% of maltodextrin, 1.5-2.5% of xylitol, 0.8-1.2% of magnesium stearate and 13-17% of descurainia sophia total flavone, wherein the descurainia sophia total flavones, a quarter of beta-cyclodextrin and a third of maltodextrin are mixed together and are prepared into 1.2 g/mL of mixed solution with distilled water, the distilled water is subjected to spray drying to obtain particles, the xylitol, the magnesium stearate, three quarters of beta-cyclodextrin and two thirds of maltodextrin are added into the particles, and the mixture is pressed into the descurainia sophia total-flavone tablets. The descurainia sophia total-flavone tablets are scientific and reasonable in formula and convenient to use, has the effects of relieving cough, eliminating phlegm and relieving asthma, is effectively used for treating cough and asthma and eliminating excessive phlegm and is good in effect, and the medicinal value of descurainia Sophia is developed.

Description

technical field [0001] The invention relates to medicine, in particular to a Tinglizi total flavonoid tablet for relieving cough, eliminating phlegm and relieving asthma. Background technique [0002] The content of total flavonoids in Tinglizi is about 0.5% of the weight of the original medicinal materials, accounting for more than 55% of the total flavonoids extract of Tinglizi, mainly containing some flavonoids and flavonoid glycosides, mainly including kaempferol-3-O -β-D-glucopyranosyl-7-O-β-D-gentiobioside, quercetin-3-O-β-D-glucopyranosyl-7-O-β-D-gentioside Diglycoside, Isorhamnetin-3-O-β-D-Glucopyranosyl-7-O-β-D-gentiobioside, Isorhamnetin-3,7-Di-O-β-D -Glucopyranoside, quercetin-3,7-di-O-β-D-glucopyranoside and other components (Feng Sanwei et al. Study on the chemical composition of each chemical fractionation of Tinglizi chinensis[J ]. World Science and Technology—Modernization of Traditional Chinese Medicine, 2015,17(3):455-463.). Pharmacological studies have ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/31A61K9/20A61P11/06A61P11/10A61P11/14
Inventor 李红伟孟祥乐郑晓珂冯卫生匡海学
Owner HENAN UNIV OF CHINESE MEDICINE
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