Inclined plate type mechanical pain-sensitivity determining device
A measuring device and sloping plate technology, applied in the field of medical devices, can solve the problems of high price, poor availability, and fragile probes, and achieve the effects of reducing experimental costs, good availability, and simple operation.
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Embodiment 1
[0030] Angle α parameter usage mode (taking rats as an example)
[0031] (1) When using this device to measure pain sensitivity, the horizontal plate 4 of the device is placed flat on the desktop, and the barbed wire 6 is set with a maximum angle as the initial angle (taking 80° as an example), and the rat is placed on the barbed wire 6, and the rat can Hold on to the barbed wire 6 tightly so that it does not slip;
[0032] (2) When the rat is not moving, the magnet 5 is adsorbed on the sole of the measured foot (taking the sole of the left rear foot as an example), so that the probe 7 on the magnet 5 is vertically aligned with the sole of the foot and touches it. If there is no pain, the movement will not occur, that is, the angle of the inclined board 2 can be gradually lowered, so that the stimulation intensity of the probe 7 can be slowly increased; once the rat’s foot is lifted, it means pain, and the inclined board 2 is fixed. At this time, the inclined board 2 correspon...
Embodiment 2
[0034] Stimulation intensity F use mode (take rats as an example)
[0035] (1) The rat to be tested needs to be weighed before using the device for measurement, and the mass is m;
[0036] (2) During the measurement, the horizontal plate 4 of the device is placed flat on the desktop, and the barbed wire 6 is set with a maximum angle as the initial angle (taking 80° as an example), and the rat is placed on the barbed wire 6, and the rat can hold the barbed wire tightly. 6 does not slip;
[0037] (3) When the rat is not moving, the magnet 5 is adsorbed on the sole of the measured foot (taking the sole of the left rear foot as an example). Pain will not cause movement, and then gradually lower the angle α of the slant plate 2. As the angle α decreases, cosα will increase, so the stimulation force F=0.25mgcosα of the probe 7 on the soles of the feet will gradually increase; Once the rat lifts its foot, it means pain, fix the inclined board 2, and record the angle α on the vertic...
Embodiment 3
[0040] Simultaneously measure the use mode of more than one set of data (take the measurement of 2 hind feet as an example)
[0041] (1) When using this device to measure pain sensitivity, the horizontal plate 4 of the device is placed flat on the desktop, and the barbed wire 6 is set with a maximum angle as the initial angle (taking 80° as an example), and the rat is placed on the barbed wire 6, and the rat can Hold on to the barbed wire 6 tightly so that it does not slip;
[0042] (2) When the rat does not move, the barbed wire 6 on its measured rear sole (the same side and the opposite side) each absorbs a magnet 5, so that the probe 7 on the magnet 5 is vertically aligned with the sole of the foot and contacts. Rats will not move if there is no pain. Gradually lower the angle α of the slant plate 2. As the angle α decreases, cos α will increase, so the stimulation force F=0.25mg cos α of the probe 7 on the soles will gradually increase. Increase; once the rat lifts the fo...
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