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Novel three-compartment infusion bag used for packaging fat emulsion, amino acid and glucose injection

A technology of glucose injection and infusion bag, which is applied in the field of medicine, can solve the problems of increasing the chance of infection of patients and the difficulty of better utilization of effective nutrients, and achieve the effect of reducing the risk of pollution

Inactive Publication Date: 2016-01-06
LIAONING HAISCO PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The infusion of multiple bottles in turn not only brought troubles for medical staff to repeatedly change bottles, constantly check, and adjust the drip rate, but more importantly, it also brought problems to patients such as increased chances of infection and difficulty in making better use of effective nutrients

Method used

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  • Novel three-compartment infusion bag used for packaging fat emulsion, amino acid and glucose injection
  • Novel three-compartment infusion bag used for packaging fat emulsion, amino acid and glucose injection
  • Novel three-compartment infusion bag used for packaging fat emulsion, amino acid and glucose injection

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0034] The preparation process of the three-chamber transfusion bag of the present invention

[0035]

[0036]

[0037]*: The three-layer co-extrusion film for infusion is made by hot pressing, and the outer film of the three-layer co-extrusion film for infusion is composed of polypropylene and styrene-ethylene-butadiene block copolymer (7.5%); The middle film consisted of polypropylene / polyethylene, styrene-ethylene-butadiene block copolymer (85%); the inner film consisted of polypropylene (7.5%).

[0038] **: The three-layer co-extrusion film for infusion comes from PolyCine GmbH, where the source of the outer film is code CFA100 (7.5%); the source of the middle film is code BFX101 (85%); the source of the inner film is code BFX284 (7.5%) .

[0039] The percentages of the above-mentioned films are thickness parameters, that is, the proportions of the three layers of films to the total thickness.

experiment example 1

[0040] Experimental Example 1 - Appearance Inspection

[0041] Take 10 each of Examples 1-32 of the present invention, respectively, and visually observe them in a bright place with natural light, all of which are transparent, smooth, and free of foreign matter visible to the naked eye. There are no cracks, fissures, pores, colored inclusions and foreign matter deposits at the mouth tube interface.

experiment example 2

[0042] Experimental Example 2 - Identification

[0043] (1) Microscopic features: Take 10 each of Examples 1-32 of the present invention, cut them into appropriate thicknesses, observe under a microscope, and the cross-section shows clear three layers.

[0044] (2) Actual welding strength: Take Examples 1-32 of the present invention and measure them according to the method of composite bags in the heat sealing strength measurement method (YBB00122003), and the average value of each heat sealing part is not less than 20N / 15 mm.

[0045] (3) Insufficient weld strength: take Examples 1-32 of the present invention, measure according to the method for the composite bag in the heat seal strength measurement method (YBB00122003) respectively, and the average value of each heat seal position is (5N-12N) / 15 mm .

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Abstract

The invention belongs to the technical field of medical technology, in particular to a novel three-compartment infusion bag used for packaging fat emulsion, amino acid and glucose injection.Pseudo soldering compartments are formed by a hot pressing method at positions where all compartments are connected. The compartments exert effect of separating medicine liquid in the three compartments during process of storing and transporting medicine liquid. During application, the compartments can be conveniently opened up only by applying certain pressure such that the three compartments are communicated and medicine liquid in the three compartments is mixed. The embodiment of the novel three-compartment infusion bag used for packaging fat emulsion, amino acid and glucose injection has following beneficial effects: mis-operation easily occurring when ordinary infusion is mixed is avoidable so that problems such as cross contamination arising from mixing of particles generated by puncturing are decreased; stability of infusion is improved; and a three-compartment package well satisfies the requirements for clinically safe, rapid and convenient infusion so that an improvement effect of preparation stability is more obvious.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a three-layer co-extruded three-chamber infusion bag for packaging parenteral nutrition products. Background technique [0002] Parenteral nutrition is mainly suitable for patients with gastrointestinal dysfunction or failure. It supplies the nutritional elements needed by patients via intravenous route, mainly including caloric carbohydrates, fat emulsions, amino acids, vitamins, electrolytes and trace elements. From the perspective of body metabolism, the two basic elements for protein synthesis are energy and nitrogen sources, both of which are indispensable. The former (mainly glucose and fat) provide the driving force for synthesis, while the latter (essential amino acids) are the raw materials for protein synthesis. Only when caloric substances and nitrogenous substances are input at the same time, and electrolytes, vitamins, etc. are also included, can anabol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J1/10A61L2/04
Inventor 程福军姜峰冯卫
Owner LIAONING HAISCO PHARMACEUTICAL CO LTD