Catalyst for synthesizing ethyl 3,3,3-trifluoropropionate and preparation method thereof

Abstract

The invention provides a catalyst for synthesizing ethyl 3,3,3-trifluoropropionate and a preparation method thereof. The catalyst is composed of tungsten oxide and TS-1 molecular sieve, wherein the TS-1 molecular sieve is 1%-10% of the mass of the tungsten oxide. It is prepared by mixing tungsten oxide and TS-1 molecular sieve, fully grinding, and then roasting. The catalyst is used in catalytic synthesis of ethyl 3,3,3-trifluoropropionate, has high product selectivity, simple preparation method, no corrosion to equipment, easy separation of catalyst, recyclable use, and good performance Industrial application prospects.

Description

technical field [0001] The invention relates to a catalyst for synthesizing ethyl 3,3,3-trifluoropropionate and a preparation method thereof, belonging to the field of catalysts. Background technique [0002] Fluorine-containing organic compounds have unique physical and chemical properties and physiological activities, so they are widely used in medicine, pesticides and other fields. The introduction of fluorine atoms into organic molecules through fluorine-containing building blocks is a common method for the synthesis of fluorine-containing organic compounds. In recent years, including CF 3 Group C 3 Fluorine-containing building blocks have been developed rapidly, among which 3,3,3-trifluoroethyl propionate, as a new type of fluorine-containing building blocks, has been gradually used in the synthesis of fluorine-containing medicines and pesticides, and has become an important One of the fluorine intermediates. [0003] The traditional synthesis method of ethyl 3,3,3-...

AI Technical Summary

Problems solved by technology

Although concentrated sulfuric acid has the advantages of relatively low price and high activity, this method is not ideal. The main disadvantages are: concentrated sulfuric acid is highly corrosive and easy to corrode equipment; concentrated sulfuric acid is not easy to separate as a homogeneous catalyst. It is difficult to recycle and reuse, and the waste acid produced is easy to cause environmental pollution; the strong oxidizing and dehydrating properties of concentrated sulfuric acid will cause side reactions such as sulfuric acid esters, ethers or unsaturated compounds, which will bring great benefits to further refining and raw material recovery. difficulty

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